公开(公告)号：US4249538A

公开(公告)日：1981-02-10

申请号：US968854

申请日：1978-12-12

申请人： Toshimitsu Musha ,  Kenichi Harumi ,  Yasuaki Teramachi ,  Toshiyuki Kanou

发明人： Toshimitsu Musha ,  Kenichi Harumi ,  Yasuaki Teramachi ,  Toshiyuki Kanou

IPC分类号： A61B5/044 ,  A61B5/04 ,  A61B5/0408 ,  A61B5/0432

CPC分类号： A61B5/04325 ,  A61B5/04007 ,  A61B5/04085 ,  G06F19/3406 ,  Y10S505/846

摘要： An improved electronic clinic apparatus includes a group of a number of probes positioned on or above at least one body surface of a person subjected to a clinic operation. It includes further a multichannel amplifier for amplifying electrical potential sensed at each of the probes. A multiplexer is connected with the amplifier at its output and an AD-amplifier is connected with the multiplexer at its output. An electronic computer for treatment of digital outputs from the AD-amplifier is provided. Various and several display units are provided for displaying outputs from the computer. Control means are provided between the multiplexer and the computer for successive read-out of the sensed potentials at the grouped probes and within a variable operating period, and for providing a pause period thereafter. The variable operating period added with the pause period defines a predetermined functional cycle period such as 2 ms. The subject apparatus removes improper probe signal(s) including inhibitingly large noise signals and replenishes properly calculated and established imaginary signals in place thereof. The removal and replenishing job is performed during said pause period.

摘要翻译： 一种改进的电子诊所装置包括定位在经过临床操作的人的至少一个身体表面上或上方的多个探针的组。 它还包括用于放大每个探针感测的电位的多通道放大器。 多路复用器在其输出端与放大器连接，并且AD放大器在其输出端与多路复用器连接。 提供了用于处理来自AD放大器的数字输出的电子计算机。 提供了用于显示来自计算机的输出的各种和多个显示单元。 在多路复用器和计算机之间提供控制装置，用于连续地读出分组探头处的感测电位，并在可变运行周期内，以及之后提供暂停时段。 添加了暂停时段的可变运行周期定义了预定的功能周期，例如2ms。 主题装置去除包括抑制性大的噪声信号的不适当的探测信号，并补充正确计算和建立的虚拟信号。 在所述暂停时段期间执行移除和补充作业。

公开(公告)号：US07734337B2

公开(公告)日：2010-06-08

申请号：US12073462

申请日：2008-03-05

申请人： Toshimitsu Musha ,  Haruyasu Matsuzaki

发明人： Toshimitsu Musha ,  Haruyasu Matsuzaki

IPC分类号： A61B5/04

CPC分类号： A61B5/048 ,  A61B5/4088

摘要： For measuring a brain local activity, a predetermined frequency bandwidth wider than a frequency bandwidth of alpha waves of scalp potentials is divided into a predetermined number of frequency banks each having a fixed frequency width, data of each divided frequency bank is divided into segments of a predetermined duration on a time axis, a Z-score of the subject is determined from a first mean value of normalized power variances determined for the segments and a second mean value of normalized power variances predetermined in the same manner as the first mean value for a predetermined normal person group and a standard deviation of the normalized power variances in the group, and a mean value of the Z-scores determined over all of the frequency banks is mapped on a brain surface for each sensor, whereby a template of a specified brain disorder and likelihood of a subject to a specified brain disorder are calculated.

摘要翻译： 为了测量脑局部活动，将比头皮电位α波的频带宽度宽的预定频率带宽分成预定数量的频率组，每个频率组具有固定的频率宽度，每个分频频率组的数据被划分为 在时间轴上的预定持续时间，从针对段确定的归一化功率方差的第一平均值和与第一平均值相同的预定的归一化功率方差的第二平均值来确定对象的Z分数 预定的正常人群和组中归一化的功率方差的标准偏差，并且将所有频率组上确定的Z分数的平均值映射到每个传感器的脑表面上，由此指定大脑的模板 计算受试者对特定脑障碍的障碍和可能性。

公开(公告)号：US06741888B2

公开(公告)日：2004-05-25

申请号：US09993910

申请日：2001-11-27

申请人： Toshimitsu Musha ,  Takashi Asada

发明人： Toshimitsu Musha ,  Takashi Asada

IPC分类号： A61B504

CPC分类号： A61B5/0476 ,  A61B5/04008 ,  A61B5/048 ,  A61B5/4088

摘要： A proper frequency component of EEG is selected so that its scalp potential becomes smooth in a normal subject. When the brain function is impaired, non-uniformity of neuronal activity is detected in spatial as well as temporal fluctuations in the observed scalp potential of properly filtered EEG (usually the alpha component). The statistical parameters derived from dipolarity values of such a properly selected EEG component determine the state of the brain, in which whether the subject is normal or demented is judged in the early stage of dementia by comparing the obtained parameters with their threshold values. This invention presents a reliable, inexpensive, easy-to-handle and non-invasive method for sensitive screening of dementia and monitoring progress of dementia which also allows optimizing medication and treatment for dementia.

摘要翻译： 选择EEG的适当频率分量，使其头皮电位在正常受试者中变得平滑。 当脑功能受损时，在正确过滤的EEG（通常为α分量）的观察到的头皮电位的空间和时间波动中检测到神经元活动的不均匀性。 从这种适当选择的EEG组分的双极性值得到的统计学参数通过将获得的参数与其阈值进行比较来确定脑的状态，其中在痴呆早期判断受试者是正常还是痴呆。 本发明提供了一种可靠，便宜，易于处理和非侵入性的敏感痴呆筛查方法，并监测痴呆症进展情况，该方法还可优化药物治疗和痴呆症治疗。

公开(公告)号：US5797853A

公开(公告)日：1998-08-25

申请号：US852672

申请日：1997-05-07

申请人： Toshimitsu Musha ,  Omi Terasaki

发明人： Toshimitsu Musha ,  Omi Terasaki

IPC分类号： A61B5/0476 ,  A61B5/04 ,  A61B5/05

CPC分类号： A61B5/04008 ,  A61B5/0476 ,  A61B5/4088

摘要： An apparatus and method for automatically determining an individual's level of brain function is provided. EEG or MEG signals are collected amplified and digitized. The signals are then passed to a computer comprising a CPU, ROM and RAM, an input interface for collecting and filtering the scalp potential signals and an output interface for displaying the resulting information on a display device such as a printer or CRT. The computer determines the position of these signals in reference to the interpolated 3-D geometry of the subject's head. The dipolarity of a particular point is iteratively and empirically derived by comparing the values of these measured signals to a test signal and the error between the two is minimized. The procedure is repeated for the complete series of electrodes placed on the skull. The mean dipolarity of a subject is then determined for a given time frame. The subject's dipolarity is then compared against that of age matched subjects and scaled so that an estimation of the subjects degree of cognitive loss is determined.

摘要翻译： 提供了一种用于自动确定个体脑功能水平的装置和方法。 EEG或MEG信号被收集放大和数字化。 然后将信号传送到包括CPU，ROM和RAM的计算机，用于收集和过滤头皮电位信号的输入接口和用于在诸如打印机或CRT的显示装置上显示所得到的信息的输出接口。 计算机根据对象头部的内插3-D几何结构确定这些信号的位置。 通过将这些测量信号的值与测试信号进行比较，迭代地和经验地导出特定点的二极性，并且将两者之间的误差最小化。 对于放置在颅骨上的完整系列电极重复该过程。 然后在给定的时间范围内确定受试者的平均二极性。 然后将受试者的双极性与年龄匹配的受试者进行比较，并进行比例，以便确定受试者的认知损失程度。

公开(公告)号：US20090171181A1

公开(公告)日：2009-07-02

申请号：US11658441

申请日：2005-07-15

申请人： Yoshiyuki Kumada ,  Toshimitsu Musha

发明人： Yoshiyuki Kumada ,  Toshimitsu Musha

IPC分类号： A61B5/0478

CPC分类号： A61B5/0478 ,  A61B5/4088

摘要： It is possible for the tips of all the electrodes to make contact with the scalp with greater reliability even with respect to different subjects, by adaptation to individual differences in the heads of subjects, and the functional status of the brain can be detected with greater accuracy. A brain function detection apparatus is provided which has a hat-shaped apparatus main body for mounting on the head of a subject, a plurality of electrodes for detecting brain wave signals, which are mounted in the apparatus main body separated from each other at intervals, and which are arranged in contact with the scalp, and the apparatus main body has a plurality of holder pieces in which at least one electrode is mounted, a bendable belt for linking the holder pieces, and a holder piece interval-adjusting apparatus for adjusting the distance between the holder pieces.

摘要翻译： 所有电极的尖端都可以通过适应受试者头部的个体差异，即使相对于不同的受试者也可以更高的可靠性与头皮接触，并且可以以更高的精度检测大脑的功能状态 。 提供一种脑功能检测装置，其具有用于安装在被检体头部的帽状装置主体，安装在设备主体中的多个用于检测脑波信号的电极，其间隔隔开， 并且其设置成与头皮接触，并且设备主体具有多个保持件，其中安装有至少一个电极，用于连接保持件的可弯曲带，以及用于调节保持件的间隔调节装置 支架之间的距离

公开(公告)号：US06349231B1

公开(公告)日：2002-02-19

申请号：US08904043

申请日：1997-07-31

申请人： Toshimitsu Musha

发明人： Toshimitsu Musha

IPC分类号： A61B500

CPC分类号： A61B5/16 ,  A61B5/0482 ,  A61B5/04842 ,  A61B5/7257 ,  A61B5/7267

摘要： An apparatus and a method for automatically determining the present will of a human subject. The characteristic values of the subject are detected and output signals corresponding to the detected characteristic values are produced, amplified and digitized. A set of state variables for each selected frequency sub-band of a selected frequency band for each of the output signals is determined. Sets of reference weights and sets of reference biases for a neural network from sets of state reference variables corresponding to known wills are formed. Each of the sets of state variables, the sets of reference weights and the sets of reference biases are applied to the neural network to determine present will of the subject. The present will of the subject can be displayed or used to control an external device, such as a robot.

摘要翻译： 一种用于自动确定人类受试者的意愿的装置和方法。 检测对象的特征值，产生与检测出的特征值对应的输出信号，进行放大并数字化。 确定每个输出信号的所选频带的每个选定频率子带的一组状态变量。 形成了与已知意愿相对应的状态参考变量的集合，用于神经网络的参考权重集合和参考偏差集合。 状态变量集合，参考权重集合和参考偏差集合被应用于神经网络以确定对象的意愿。 可以显示或使用该主题的当前意图来控制诸如机器人的外部设备。

公开(公告)号：US4661816A

公开(公告)日：1987-04-28

申请号：US539239

申请日：1983-10-05

申请人： Toshimitsu Musha ,  Eichi Kiuchi ,  Toshihiko Hagisawa

发明人： Toshimitsu Musha ,  Eichi Kiuchi ,  Toshihiko Hagisawa

IPC分类号： H03H21/00 ,  G01S13/524 ,  H03H17/00 ,  H03H17/02 ,  H04B3/04 ,  H04B3/23 ,  G01S7/30

CPC分类号： G01S13/5244

摘要： An adaptive radar signal processor is operable to effectively suppress clutters and extract a target signal with a high degree of accuracy and includes a memory storing two-dimensional radar data corresponding to range and azimuthal directions, multipliers multiplying each of data of the same range but different azimuthal direction read out from the memory, an adder generating the added data of the multipliers as an estimated data, and a weighting coefficient determinater which determines the optimum weighting coefficients based upon the stored radar data so that the difference between the radar data and the estimated data at an observing position is minimized, and produces the difference data as a clutter-suppressed radar data.

摘要翻译： 自适应雷达信号处理器可操作以有效地抑制杂波并以高精度提取目标信号，并且包括存储对应于范围和方位角方向的二维雷达数据的存储器，乘法器将相同范围但不同的数据相乘 从存储器读出的方位角方向，产生乘法器的相加数据作为估计数据的加法器，以及基于所存储的雷达数据确定最佳加权系数的加权系数确定器，使得雷达数据与估计的 在观测位置的数据被最小化，并且产生差分数据作为杂波抑制的雷达数据。

公开(公告)号：US4242682A

公开(公告)日：1980-12-30

申请号：US71614

申请日：1979-08-31

申请人： Toshimitsu Musha ,  Matsuo Sekine ,  Takeru Irabu ,  Eichi Kiuchi

发明人： Toshimitsu Musha ,  Matsuo Sekine ,  Takeru Irabu ,  Eichi Kiuchi

IPC分类号： G01S7/32 ,  G01S7/292 ,  G01S13/52 ,  G01S13/522 ,  G01S7/30

CPC分类号： G01S7/2921

摘要： A moving target indication radar rejects clutter by employing a suppressor having a threshold level variable in accordance with the detected shape parameter .eta. of the Weibull distribution.

摘要翻译： 移动目标指示雷达通过采用根据检测到的威布尔分布的形状参数eta具有阈值电平变化的抑制器来拒绝杂波。

公开(公告)号：US20090105603A1

公开(公告)日：2009-04-23

申请号：US12073462

申请日：2008-03-05

申请人： Toshimitsu Musha ,  Haruyasu Matsuzaki

发明人： Toshimitsu Musha ,  Haruyasu Matsuzaki

IPC分类号： A61B5/0478

CPC分类号： A61B5/048 ,  A61B5/4088

摘要： For measuring a brain local activity, a predetermined frequency bandwidth wider than a frequency bandwidth of alpha waves of scalp potentials is divided into a predetermined number of frequency banks each having a fixed frequency width, data of each divided frequency bank is divided into segments of a predetermined duration on a time axis, a Z-score of the subject is determined from a first mean value of normalized power variances determined for the segments and a second mean value of normalized power variances predetermined in the same manner as the first mean value for a predetermined normal person group and a standard deviation of the normalized power variances in the group, and a mean value of the Z-scores determined over all of the frequency banks is mapped on a brain surface for each sensor, whereby a template of a specified brain disorder and likelihood of a subject to a specified brain disorder are calculated.

摘要翻译： 为了测量脑局部活动，将比头皮电位α波的频带宽度宽的预定频率带宽分成预定数量的频率组，每个频率组具有固定的频率宽度，每个分频频率组的数据被划分为 在时间轴上的预定持续时间，从针对段确定的归一化功率方差的第一平均值和与第一平均值相同的预定的归一化功率方差的第二平均值来确定对象的Z分数 预定的正常人群和组中归一化的功率方差的标准偏差，并且将所有频率组确定的Z分数的平均值映射到每个传感器的脑表面上，由此指定大脑的模板 计算受试者对特定脑障碍的障碍和可能性。

公开(公告)号：US20080027345A1

公开(公告)日：2008-01-31

申请号：US11630318

申请日：2005-06-21

申请人： Yoshiyuki Kumada ,  Toshimitsu Musha

发明人： Yoshiyuki Kumada ,  Toshimitsu Musha

IPC分类号： A61B5/0476

CPC分类号： A61B5/0478

摘要： The labor involved in cleaning for each examination is reduced, the examination can be carried out hygienically, and the convenience of use is improved. An electrode apparatus for detecting brain waves which is arranged in contact with the scalp and which detects brain wave signals is provided. The electrode apparatus for detecting brain waves comprises a rod-shaped electrode apparatus main body having an electrode disposed at the tip thereof, a cap which is mountable on the tip of the electrode apparatus main body and which has an elastic member which contains an electrolyte and which is disposed making close contact so as to cover the electrode, and a connection means which detachably connects the cap to the electrode apparatus main body.

摘要翻译： 每次检查所涉及的劳动力减少，可以进行卫生检查，提高使用便利性。 提供一种用于检测与头皮接触并且检测脑波信号的脑波的电极装置。 用于检测脑电波的电极装置包括：杆状电极装置主体，其具有设置在其前端的电极，盖可安装在电极装置主体的前端，并且具有包含电解质的弹性构件， 其被设置为紧密接触以覆盖电极;以及连接装置，其将盖可拆卸地连接到电极装置主体。