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公开(公告)号：US07657324B2
公开(公告)日：2010-02-02
申请号：US10617881
申请日：2003-07-14
IPC分类号： A61N1/05
CPC分类号： A61N1/0565 , A61N1/056 , A61N1/0573
摘要： A seal adapted for use with medical devices is provided. The medical device may be a lead having a distal tip adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead assembly in one embodiment includes an atraumatic tip. A seal is provided within the lead tip assembly, which prevents or limits further entry of fluids through the lead tip. The lead may be a left ventricular lead with a hemostasis mechanism provided therewithin.
摘要翻译： 提供适于与医疗装置一起使用的密封件。 医疗装置可以是具有适于植入在心脏上或周围的远端的引线，并且用于连接到用于监测或刺激心脏活动的系统。 在一个实施例中的引线组件包括无创伤的尖端。 在引线端头组件内提供密封件，其防止或限制流体进一步进入引线尖端。 铅可以是在其中设置有止血机构的左心室导联。
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公开(公告)号：US07628801B2
公开(公告)日：2009-12-08
申请号：US10128997
申请日：2002-04-23
IPC分类号： A61F7/00
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having an atraumatic tip is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and are biased toward a vessel wall by a preformed biased portion. Near the distal end, the lead has an optional tapered portion and a flexible portion, where the flexible portion is more flexible than the biased portion.
摘要翻译： 具有无创尖端的引线适于植入在冠状脉管系统内或心脏周围并用于连接到信号发生器。 引线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并且被预先偏置的部分偏压到血管壁。 在远端附近，引线具有可选的锥形部分和柔性部分，其中柔性部分比偏置部分更柔性。
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公开(公告)号：US07412290B2
公开(公告)日：2008-08-12
申请号：US10968305
申请日：2004-10-20
IPC分类号： A61N1/372
CPC分类号： A61N1/0573 , A61N1/0565
摘要： A seal adapted for use with medical devices is provided with a lead having a distal tip electrode. The distal tip of the lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead can include a fixation helix for securing the electrode to cardiac tissue. The lead assembly can alternatively include an open lumen lead tip. A seal is provided within the lead tip assembly such that the seal is expanded to prevent or limit further entry of fluids through the lead tip. The seal includes an expandable matrix, such as a hydrogel. The seal is formed on or within the lead when the lead and the seal comes into contact with a fluid and expands. The seal is also formed as a plug which is deployed through the medical device, and expands as the plug absorbs fluid. A housing incorporating the seal can also be attached to a portion of the medical device to provide the seal.
摘要翻译： 适于与医疗装置一起使用的密封件设置有具有远端尖端电极的引线。 引线的远端适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。 引线可以包括用于将电极固定到心脏组织的固定螺旋。 导线组件可以替代地包括开放的管腔引线端头。 在引线端头组件内设置密封件，使得密封件被膨胀以防止或限制流体进一步通过引线头进入。 密封件包括可膨胀基质，例如水凝胶。 当铅和密封件与流体接触并膨胀时，密封件形成在引线上或内部。 密封件还形成为通过医疗装置展开的塞子，并且当塞子吸收流体时膨胀。 结合密封件的壳体也可以附接到医疗装置的一部分以提供密封。
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14.发明申请公开(公告)号：US20070067008A1
公开(公告)日：2007-03-22
申请号：US11600807
申请日：2006-11-16
申请人： Avram Scheiner , Ronald Heil , Peter Kelley , Bruce Tockman , Randy Westlund , Jay Warren
发明人： Avram Scheiner , Ronald Heil , Peter Kelley , Bruce Tockman , Randy Westlund , Jay Warren
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead for monitoring or stimulating cardiac activity is provided. The lead is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead body has one or more electrodes associated therewith. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and urged into intimate contact a vessel wall.
摘要翻译： 提供监测或刺激心脏活动的潜在客户。 引线适于植入在冠状脉管系统内部或其周围的心脏上，并用于连接到信号发生器。 引线体具有与其相关联的一个或多个电极。 导线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并被促使与血管壁紧密接触。
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公开(公告)号：US20070049978A1
公开(公告)日：2007-03-01
申请号：US11554135
申请日：2006-10-30
IPC分类号： A61N1/00
CPC分类号： A61N1/36514 , A61N1/3622 , A61N1/365 , A61N1/368 , A61N1/3712
摘要： A method for allowing cardiac signals to be sensed and pacing pulse vectors to be delivered between two or more electrodes. In one embodiment, cardiac signals are sensed and pacing pulse vectors are delivered between least one of a first left ventricular electrode and a second left ventricular electrode. Alternatively, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrodes and a first supraventricular electrode. In addition, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrode, the first supraventricular electrode and a conductive housing. In an additional embodiment, a first right ventricular electrode is used to sense cardiac signals and provide pacing pulses with different combinations of the first and second left ventricular electrodes, the first supraventricular electrode and the housing.
摘要翻译： 一种用于允许感测心脏信号的方法和用于在两个或更多个电极之间递送起搏脉冲矢量的方法。 在一个实施例中，感测心脏信号，并且起搏脉冲向量在第一左心室电极和第二左心室电极中的至少一个之间递送。 或者，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极和第一室上电极的不同组合之间递送。 此外，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极，第一室上电极和导电壳体的不同组合之间递送。 在另外的实施例中，第一右心室电极用于感测心脏信号并且提供具有第一和第二左心室电极，第一室上电极和外壳的不同组合的起搏脉冲。
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公开(公告)号：US06584362B1
公开(公告)日：2003-06-24
申请号：US09651340
申请日：2000-08-30
申请人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren
发明人： Avram Scheiner , Ronald W. Heil, Jr. , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren
IPC分类号： A61N105
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead for monitoring or stimulating cardiac activity is provided. The lead is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead body has one or more electrodes associated therewith. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and urged into intimate contact a vessel wall. A method for implanting the lead into the coronary vasculature is also provided, the method comprising the steps of inserting a stylet into the lead, inserting the lead into the coronary sinus, advancing the lead from the coronary sinus toward the toward the left atrium and into a coronary vein, removing the stylet, and sensing and pacing the heart. Alternatively, the method comprises placing a guide catheter into the coronary sinus, threading a guide wire into the coronary veins, pushing the lead over the guide wire and into the coronary sinus or the coronary vein, and sensing and pacing the heart via the lead in its implanted site in the coronary sinus or the coronary vein.
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公开(公告)号：US20110178566A1
公开(公告)日：2011-07-21
申请号：US13075244
申请日：2011-03-30
申请人： Jeffrey E. Stahmann , Bruce Tockman , Randy Westlund , Rene H. Wentkowski , Russell E. Anderson
发明人： Jeffrey E. Stahmann , Bruce Tockman , Randy Westlund , Rene H. Wentkowski , Russell E. Anderson
IPC分类号： A61N1/365
CPC分类号： A61N1/36514 , A61N1/3622 , A61N1/365 , A61N1/368 , A61N1/3712
摘要： A method for allowing cardiac signals to be sensed and pacing pulse vectors to be delivered between two or more electrodes. In one embodiment, cardiac signals are sensed and pacing pulse vectors are delivered between at least one of a first left ventricular electrode and a second left ventricular electrode. Alternatively, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrodes and a first supraventricular electrode. In addition, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrode, the first supraventricular electrode and a conductive housing. In an additional embodiment, a first right ventricular electrode is used to sense cardiac signals and provide pacing pulses with different combinations of the first and second left ventricular electrodes, the first supraventricular electrode and the housing.
摘要翻译： 一种用于允许感测心脏信号的方法和用于在两个或更多个电极之间递送起搏脉冲矢量的方法。 在一个实施例中，感测心脏信号，并且起搏脉冲矢量在第一左心室电极和第二左心室电极中的至少一个之间递送。 或者，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极和第一室上电极的不同组合之间递送。 此外，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极，第一室上电极和导电壳体的不同组合之间递送。 在另外的实施例中，第一右心室电极用于感测心脏信号并且提供具有第一和第二左心室电极，第一室上电极和外壳的不同组合的起搏脉冲。
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公开(公告)号：US07674245B2
公开(公告)日：2010-03-09
申请号：US09876876
申请日：2001-06-07
申请人： Bruce Tockman , Randy Westlund
发明人： Bruce Tockman , Randy Westlund
IPC分类号： A61M5/00
CPC分类号： A61M25/0041 , A61M25/0105 , A61M25/0136
摘要： A catheter assembly includes an outer catheter member having a distal flexible end. An inner catheter member is movably disposed within the outer catheter member. Optionally, a handle assembly is coupled with the outer catheter member and the inner catheter member, where the handle assembly is adapted to slide the inner catheter member relative to the outer catheter member.
摘要翻译： 导管组件包括具有远端柔性端部的外导管构件。 内导管构件可移动地设置在外导管构件内。 可选地，手柄组件与外部导管构件和内部导管构件联接，其中手柄组件适于相对于外部导管构件滑动内部导管构件。
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公开(公告)号：US20100049288A1
公开(公告)日：2010-02-25
申请号：US12608402
申请日：2009-10-29
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having pre-formed biased portion is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and are biased toward a vessel wall by the preformed biased portion, which operates to fixate the lead against the vessel wall.
摘要翻译： 具有预形成偏置部分的引线适于植入在冠状脉管系统内部或周围的心脏上，并用于连接到信号发生器。 引线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并且被预先设定的偏压部分偏压到血管壁，该部分操作以将引线固定在血管壁上。
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公开(公告)号：US20070239249A1
公开(公告)日：2007-10-11
申请号：US11762887
申请日：2007-06-14
申请人： Bruce Tockman , Randy Westlund , Gwen Crevensten , Lili Liu , Chris Zerby , Jay Warren
发明人： Bruce Tockman , Randy Westlund , Gwen Crevensten , Lili Liu , Chris Zerby , Jay Warren
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： An apparatus includes a lead body extending from a proximal end to a distal end and having an intermediate portion therebetween. The lead body includes two or more individually insulated conductors, where a first conductor traverses along less than an entire length of the lead body and a second conductor traverses from the proximal end to the distal end of the lead body. Optionally, the first conductor has a different material than the second conductor, for instance having differing electrical properties and/or differing stiffnesses. A method includes varying the stiffness of a coiled conductor assembly including winding a plurality of conductors to form the coiled conductor assembly, and pulling at least one loop of a first conductor away from the coiled conductor assembly.
摘要翻译： 一种装置包括从近端延伸到远端并且在其间具有中间部分的引线体。 引线体包括两个或更多个单独绝缘的导体，其中第一导体沿着引线主体的小于整个长度横穿，并且第二导体从引线主体的近端穿过远端。 可选地，第一导体具有与第二导体不同的材料，例如具有不同的电特性和/或不同的刚度。 一种方法包括改变线圈导体组件的刚度，包括缠绕多个导体以形成线圈导体组件，以及将第一导体的至少一个环拉离线圈导体组件。
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