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公开(公告)号:US11155639B2
公开(公告)日:2021-10-26
申请号:US15778966
申请日:2016-10-12
Inventor: Yong Sung Kim , Hye Ji Choi , Ji Hee Ha
Abstract: A method for evaluating and screening a mutant inducing the high-efficiency formation of heterodimers from a human antibody heavy chain constant region mutant pair combination library in order to increase the yield of formation of human antibody heterodimeric heavy chain constant regions. A heterodimeric heavy chain constant region (heterodimeric F) library is obtained by the method. A CH3 domain mutant pair, in which the formation of the heterodimeric heavy chain constant regions is preferred in the library, forms heterodimeric heavy chain constant regions at a high yield of at least 80-90%, and also has excellent thermal stability and retains binding ability to the heavy chain constant region receptor (FcRn).
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公开(公告)号:US11148127B2
公开(公告)日:2021-10-19
申请号:US16972117
申请日:2019-06-03
Inventor: Bun Yeoul Lee , Tae Hee Kim , Hee Soo Park , Jun Won Baek , Su Jin Gwon , Sung Dong Kim
Abstract: The present invention relates to a bisphosphine ligand compound, a chromium compound prepared using same, an ethylene oligomerization catalyst system containing the chromium compound, and an ethylene oligomer preparing method, wherein the bisphosphine ligand compound is suitable for mass production and commercial processes, allows extremely high activity to be compatible with excellent economical benefit, and increases selectivity for ethylene oligomerization reaction, thereby being able to be used to manufacture 1-hexene and/or 1-octene at high yield.
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公开(公告)号:US11132603B2
公开(公告)日:2021-09-28
申请号:US15687773
申请日:2017-08-28
Inventor: Tae Shik Shon , Seok Jun Lee , Seok Cheol Lee , Hyung Uk Yoo
Abstract: Provided is a method for generating a one class model based on a data frequency. The method for generating a one class model based on a data frequency includes: generating, by a machine learning apparatus, a plurality of spatial coordinates by arranging a plurality of learning data in corresponding coordinates in a feature space; classifying, by the machine learning apparatus, the plurality of spatial coordinates into a plurality of internal coordinates PI and a plurality of external coordinates PO based on a frequency of the learning data arranged in the respective spatial coordinates which belong to the plurality of spatial coordinates; and generating, by the machine learning apparatus, a one class model based on the plurality of internal coordinates PI based on mutual spatial distances of the plurality of external coordinates PO and the plurality of internal coordinates PI.
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204.
公开(公告)号:US20210288664A1
公开(公告)日:2021-09-16
申请号:US17178356
申请日:2021-02-18
Inventor: Myung Hoon SUNWOO , Seung Yong KIM
Abstract: A method for decoding a signal encoded with polar codes by a decoding system is provided. The method comprises receiving, from a transmission system, a signal in which a plurality of cyclic redundancy checks (CRCs) are encoded by the polar codes, the plurality of CRCs being inserted into positions determined based on a plurality of information bits, a number of the plurality of information bits and a total code length, and decoding a code section including bits ranging from a first bit of the signal to a position where a last bit of a first CRC is inserted. The method further comprises re-performing successive cancellation flip decoding for the decoded code section, or determining whether to decode a next code section adjacent to the decoded code section, based on whether a CRC is detected in the decoded code section.
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公开(公告)号:US20210271090A1
公开(公告)日:2021-09-02
申请号:US17170269
申请日:2021-02-08
Inventor: Bongsu SHIN , Jesung KOH , Geeyoung SUNG , Hongseok LEE , Dongjin KIM , Baekgyeom KIM
IPC: G02B27/01 , G02B30/34 , H04N13/344 , H04N13/128 , H04N13/366
Abstract: Provided is an image display device including a display element configured to modulate light to form an image; a light transfer unit configured to transmit the image formed by the display element to eyes of an observer, the light transfer unit comprising a focusing member; and a driver configured to drive the display element to change a position of the display element, the driver including: a first actuator comprising a deformable wire; a housing that fixes a first end and a second end of the deformable wire; and an operating structure through which the deformable wire is routed, wherein the operating structure is configured move the display element in a first direction in conjunction with a length variation of the deformable wire, and the operating structure includes an elastic structure configured to prevent tilt with respect to an axis in the first direction.
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公开(公告)号:US20210240203A1
公开(公告)日:2021-08-05
申请号:US17159433
申请日:2021-01-27
Applicant: Hyundai Motor Company , Kia Motors Corporation , Ajou University Industry-Academic Cooperation Foundation
Inventor: Jae Jun Ha , Ilsoo Yun , Sangmin Park , Sungho Park , Harim Jeong , Cheolwoo Kwon , Jiwon Kim , Kiyeon Park
Abstract: A method of performing autonomous driving based on platooning by a moving object includes setting a moving path, determining whether platooning is allowed, transmitting moving path information to a first intelligent transportation system infrastructure when the moving object of a plurality of moving objects approaches a preset range of the first intelligent transportation system infrastructure, receiving platooning information from the first intelligent transportation system infrastructure, and performing platooning based on the platooning information, wherein the first intelligent transportation system infrastructure groups ones of the moving objects capable of platooning from among the plurality of moving objects based on the moving path information received from each of the plurality of moving objects.
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公开(公告)号:US20210237735A1
公开(公告)日:2021-08-05
申请号:US17159089
申请日:2021-01-26
Applicant: Hyundai Motor Company , Kia Motors Corporation , AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventor: Jae Jun Ha , Ilsoo Yun , Sangmin Park , Sungho Park , Harim Jeong , Cheolwoo Kwon , Jiwon Kim , Kiyeon Park
IPC: B60W30/18 , B60W50/14 , B60W30/095
Abstract: A method for providing a driving guideline in a moving object may include: triggering a driving guideline provision instruction in the moving object; based on the implemented triggering, generating, by the moving object, a driving guideline; outputting the generated driving guideline; and driving, by the moving object, based on the driving guideline.
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公开(公告)号:US20210237685A1
公开(公告)日:2021-08-05
申请号:US17162059
申请日:2021-01-29
Applicant: Hyundai Motor Company , Kia Motors Corporation , Ajou University Industry-Academic Cooperation Foundation
Inventor: Jae Jun Ha , llsoo Yun , Sangmin Park , Sungho Park , Harim Jeong , Cheolwoo Kwon , Jiwon Kim , Kiyeon Park
Abstract: A method of operating a personal mobility is provided. The method includes receiving, by a processor in the personal mobility, user identification information for a user authentication and transmitting the received user identification information to a server. A use approval message is received from the server when the user is a user registered in the server and the personal mobility is operated by the user according to the received use approval message.
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209.
公开(公告)号:US11052384B2
公开(公告)日:2021-07-06
申请号:US16346735
申请日:2016-12-12
Inventor: Bun Yeoul Lee , Eun Ho Kim , Hyun Mo Lee
IPC: C08F4/06 , B01J31/14 , C07F11/00 , B01J31/18 , C07C2/32 , B01J31/16 , C07F19/00 , C07C2/30 , C07C11/04
Abstract: The present invention relates to a chrome compound composed of non-coordinating anions and a trivalent chrome cation, a reactant of the chrome compound and a bidentate ligand, an ethylene oligomerization reaction catalyst system using the chrome compound and the reactant, and a method for preparing an ethylene oligomer using the catalyst system. Through the above conformation, the present invention can selectively produce 1-hexene and 1-octene with high activity while omitting the use of methylaluminoxane (MAO), and can provide an ethylene oligomerization process more suitable for mass production.
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公开(公告)号:US20210198340A1
公开(公告)日:2021-07-01
申请号:US17194712
申请日:2021-03-08
Inventor: Yong Sung Kim , Ye Jin Kim
IPC: C07K14/705 , A61K9/127 , A61K47/50 , C07K19/00 , G01N33/53 , G01N33/574 , G01N33/68
Abstract: A peptide that binds specifically to neuropilin-1 (NRP1) without binding to neuropilin-2 (NRP2) is provided. A fusion protein, a fusion antibody, small-molecule drug, a nanoparticle, or a liposome, which comprises the peptide, and a pharmaceutical composition for treating or preventing cancer or angiogenesis-related diseases, and a composition for diagnosing cancer or angiogenesis-related diseases are provided. A polynucleotide encoding the peptide that binds specifically to NRP1 and a method for screening the peptide that binds specifically to NRP1 are provided. An antibody heavy-chain constant region Fc-fused peptide binding specifically to NRP1 has the property of binding specifically to NRP1, and thus when it is administered in vivo, it accumulates selectively in tumor tissue, and widens the intercellular space between tumor-associated endothelial cells to promote its extravasation and increases its tumor tissue penetration.
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