摘要:
Wildtype and mice lacking the gene encoding PKCI/HINT 1 (PKC−/−) were used to assess the involvement of PKCI/HINT1 in regulating basal locomotor activity and the behavioral activating effects of the psychostimulant, amphetamine. PKCl−/− mice displayed low level of spontaneous locomotion relative to WT littermates. Acute administration of amphetamine significantly increased locomotor activity in WT mice; an effect that was enhanced in PKCl−/− mice. Microdialysis studies revealed no alteration in basal DA dynamics in the striatum and nucleus accumbens of KO mice. Similarly, the ability of acute amphetamine to increase DA levels in these brain regions was unaltered. However, a dopamine receptor agonist, apomorphine (10 mg/kg), was able to induce a significantly higher locomotor activity in PKCI−/− mice as compared with WT, suggesting there may be a dopaminergic functional change at the postsynaptic site. Our results also revealed that PKCI KO mice showed a less depression and anxiety trait than their litter mate controls (WT), which indicate that PKCI could also play a role in regulating the emotion states of brain. Together, these results indicated that PKCI/HINT1 may have a suppressive role in normal DA neurotransmission, and may also play an important role for the action of psychostimulants in schizophrenia.
摘要:
This invention discloses an easy binding machine. It mainly comprises: a main body, a scroll, a handle, a main lacing and an auxiliary lacing. The auxiliary lacing is in the rear side of the main body, and its tail is flexibly connected with the main body. There is an auxiliary hook fixed in the front end. There is an active buckle, which goes with the auxiliary lacing, in the rear of said main body. The said active buckle comprises a bottom board, left and right side walls and pin rolls. The pin roll is fixed between left and right side walls. There is a groove where corresponds to the pin roll in the bottom board. The tail of auxiliary reaches inside the active buckle from downward in the rear of active buckle's bottom board, and then circles the pin roll downward and reaches outside the active buckle through the groove on the bottom board. Since the auxiliary lacing and the main body are flexibly connected, the user can change auxiliary lacing and auxiliary hook freely as per the actual needs, which makes it more convenient to use the binding machine.
摘要:
The present invention provides a method and apparatus for enabling an application to cooperate with the running of a program. According to the invention, the playing control information of a program and the linking information of an application corresponding to the program are edited into a program playing control file. Through executing said playing control file, guided by the linking information and based on the running control information of the application, the application can download, run or stop to run cooperating with the playing of the optical disc program. The Solution of combining an application and a program into a playing control file will effectively cause the downloading and running of the application to cooperate with the playing of the program so as to ensure normal realization of corresponding functions.
摘要:
This invention is about the fastening belt with freely rotatable drag hooks, which includes two drag hooks. The said drag hooks have an upper cover and a bottom cover, with the hook fixed in the front of the drag hooks; one elastic rope to link the two drag hooks, which is made from stretchable material. Two rotatable linker and two ends of elastic rope are fixated inside the rotatable linker. The rotatable linker is connected with the rear rotation of the drag hook. The hook and the elastic rope are linked by the rotatable linker and the drag hook is linked with the rotatable linker. Thus, the drag hook can rotate freely in the elastic rope. The rope does not kink when in use, which not only prolongs the life of elastic ropes, but also reinforce the reliability of the connection between the drag link and the elastic rope.
摘要:
The disclosure provides a method for realizing a Mobile Switch Center (MSC) pool, a system for realizing an MSC pool and a Media Gateway (MGW). The method for realizing an MSC pool includes: connecting with a Base Station Controllers (BSC)/Radio Network Controller (RNC), by a Media Gateway (MGW) through the use of a common signaling point; and upon receipt of a message whose destination signaling point is the common signaling point from the BSC/RNC, determining, by the MGW, a destination MSC server of the message according to ID information carried in the message, and sending the received message to the destination MSC server. According to the present invention, the networking scheme for an MSC pool may be implemented without upgrading any BSC/RNC. The flexibility of the networking scheme for mobile communication systems may be improved, and the traffic load of the subscribers may be shared.
摘要:
This practical new model makes an improved binding machine known to the public, which includes main body, handle, ratchet wheel, roller, fastening belt, latch reed spring, control plate. Among them, the handle's side board is linked with the main section's side board through torsion spring. In this manner, when the fastening belt needs to be tightened as the binding machine is being used, the user can press down the handle which will resume its initial position with the bounce force of the torsion spring. It is not necessary for the user to push it back to the initial position after pressing the handle down. It is very easy and labor-saving with higher efficiency. Furthermore, it can also set a coil spring in the outside end of the roller. The fastening belt can withdraw inside the main section automatically, which is very convenient.
摘要:
The invention describes a method of annotating a timeline file (T) which method comprises identifying distinct key resources (K1, K2, K3, . . . , Km) in the timeline file (T), and describing a number of annotations for one or more key resources (K1, K2, K3, . . . , Km) in an annotation file (A) such that an annotation for a key resource (K1, K2, K3, . . . , Km) is tied to the key resource (K1, K2, K3, . . . , Km) corresponding to that annotation.
摘要:
A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds can be useful as factor Xa inhibitors.
摘要:
An optical disc player includes a detecting module and a creating module. The detecting module is used to detect whether to meet a branch point or an interruption point or a pause point; and the creating module is used to create a corresponding bookmark as a navigation for the subsequent broadcast to record the relevant information of a branch point or an interruption point or a pause point when meeting the branch point or the interruption point or the pause point. The playing method of the player includes: detecting whether to meet a branch point or an interruption point or a pause point, creating a corresponding bookmark as a navigation for the subsequent broadcast to record the relevant information of the branch point or the interruption point or the pause point when to meet the branch point or the interruption point or the pause point.
摘要:
A playing of method an optical disc player (10) comprises the steps of: detecting the playing status (s210) searching URLs corresponding to information which is not downloaded yet if the detected playing status is abnormal, yet (s230); downloading the information required in the normal status according to the searched-out URLs (S250) while the player is in the abnormal status.