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1.EFFICIENT SYNTHESIS OF 4,5-DIHYDRO-PYRAZOLO[3,4-c]PYRID-2-ONES 有权
标题翻译: 4,5-二羟基 - 吡唑并[3,4-c]吡啶-2-酮的有效合成公开(公告)号:US20070282106A1
公开(公告)日:2007-12-06
申请号:US11838926
申请日:2007-08-15
申请人: Boguslaw Mudryk , Nicolas Cuniere , Dau-Ming Hsieh , Lucius Rossano , Jing Liang , Bang-Chi Chen , Huiping Zhang , Rulin Zhao , Bei Wang , Adrian David
发明人: Boguslaw Mudryk , Nicolas Cuniere , Dau-Ming Hsieh , Lucius Rossano , Jing Liang , Bang-Chi Chen , Huiping Zhang , Rulin Zhao , Bei Wang , Adrian David
IPC分类号: C07D471/02
CPC分类号: C07D471/04
摘要: A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds can be useful as factor Xa inhibitors.
摘要翻译: 描述了由合适的苯肼制备下列所示类型的4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的新方法及其中间体。 这些化合物可用作因子Xa抑制剂。
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2.EFFICIENT SYNTHESIS OF 4,5-DIHYDRO-PYRAZOLO[3,4-c]PYRID-2-ONES 有权
标题翻译: 4,5-二羟基 - 吡唑并[3,4-c]吡啶-2-酮的有效合成公开(公告)号:US20080009626A1
公开(公告)日:2008-01-10
申请号:US11838932
申请日:2007-08-15
申请人: Boguslaw Mudryk , Nicolas Cuniere , Dau-Ming Hsieh , Lucius Rossano , Jing Liang , Bang-Chi Chen , Huiping Zhang , Rulin Zhao , Bei Wang , Adrian David
发明人: Boguslaw Mudryk , Nicolas Cuniere , Dau-Ming Hsieh , Lucius Rossano , Jing Liang , Bang-Chi Chen , Huiping Zhang , Rulin Zhao , Bei Wang , Adrian David
IPC分类号: C07D471/04
CPC分类号: C07D471/04
摘要: A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds can be useful as factor Xa inhibitors.
摘要翻译: 描述了由合适的苯肼制备下列所示类型的4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的新方法及其中间体。 这些化合物可用作因子Xa抑制剂。
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3.Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones 有权
标题翻译: 4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的有效合成公开(公告)号:US20060069119A1
公开(公告)日:2006-03-30
申请号:US11235647
申请日:2005-09-26
申请人: Boguslaw Mudryk , Nicolas Cuniere , Dau-Ming Hsieh , Lucius Rossano , Jing Liang , Bang-Chi Chen , Huiping Zhang , Rulin Zhao , Bei Wang , Adrian David
发明人: Boguslaw Mudryk , Nicolas Cuniere , Dau-Ming Hsieh , Lucius Rossano , Jing Liang , Bang-Chi Chen , Huiping Zhang , Rulin Zhao , Bei Wang , Adrian David
IPC分类号: C07D471/02 , A61K31/4745
CPC分类号: C07D471/04
摘要: A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds can be useful as factor Xa inhibitors.
摘要翻译: 描述了由合适的苯肼制备下列所示类型的4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的新方法及其中间体。
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4.Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones 有权
标题翻译: 4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的有效合成公开(公告)号:US07435821B2
公开(公告)日:2008-10-14
申请号:US11838932
申请日:2007-08-15
申请人: Boguslaw M. Mudryk , Nicolas Cuniere , Dau-Ming Hsieh , Lucius Rossano , Jing Liang , Bang-Chi Chen , Huiping Zhang , Rulin Zhao , Bei Wang , Adrian David
发明人: Boguslaw M. Mudryk , Nicolas Cuniere , Dau-Ming Hsieh , Lucius Rossano , Jing Liang , Bang-Chi Chen , Huiping Zhang , Rulin Zhao , Bei Wang , Adrian David
IPC分类号: C07D491/02
CPC分类号: C07D471/04
摘要: A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds can be useful as factor Xa inhibitors.
摘要翻译: 描述了由合适的苯肼制备下列所示类型的4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的新方法及其中间体。 这些化合物可用作因子Xa抑制剂。
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5.Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones 有权
标题翻译: 4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的有效合成公开(公告)号:US07579472B2
公开(公告)日:2009-08-25
申请号:US11838926
申请日:2007-08-15
申请人: Boguslaw M. Mudryk , Nicolas Cuniere , Dau-Ming Hsieh , Lucius Rossano , Jing Liang , Bang-Chi Chen , Huiping Zhang , Rulin Zhao , Bei Wang , Adrian David
发明人: Boguslaw M. Mudryk , Nicolas Cuniere , Dau-Ming Hsieh , Lucius Rossano , Jing Liang , Bang-Chi Chen , Huiping Zhang , Rulin Zhao , Bei Wang , Adrian David
IPC分类号: C07D515/02 , C07D513/02 , C07D498/02
CPC分类号: C07D471/04
摘要: A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds can be useful as factor Xa inhibitors.
摘要翻译: 描述了由合适的苯肼制备下列所示类型的4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的新方法及其中间体。 这些化合物可用作因子Xa抑制剂。
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6.Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones 有权
标题翻译: 4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的有效合成公开(公告)号:US07304157B2
公开(公告)日:2007-12-04
申请号:US11235647
申请日:2005-09-26
申请人: Boguslaw M. Mudryk , Nicolas Cuniere , Dau-Ming Hsieh , Lucius Rossano , Jing Liang , Bang-Chi Chen , Huiping Zhang , Rulin Zhao , Bei Wang , Adrian David
发明人: Boguslaw M. Mudryk , Nicolas Cuniere , Dau-Ming Hsieh , Lucius Rossano , Jing Liang , Bang-Chi Chen , Huiping Zhang , Rulin Zhao , Bei Wang , Adrian David
IPC分类号: C07D491/02
CPC分类号: C07D471/04
摘要: A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds can be useful as factor Xa inhibitors.
摘要翻译: 描述了由合适的苯肼制备下列所示类型的4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的新方法及其中间体。
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7.Process for preparing 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones 有权
标题翻译: 制备4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的方法公开(公告)号:US20060069258A1
公开(公告)日:2006-03-30
申请号:US11235510
申请日:2005-09-26
申请人: Rafael Shapiro , Lucius Rossano , Boguslaw Mudryk , Nicolas Cuniere , Matthew Oberholzer , Huiping Zhang , Bang-Chi Chen
发明人: Rafael Shapiro , Lucius Rossano , Boguslaw Mudryk , Nicolas Cuniere , Matthew Oberholzer , Huiping Zhang , Bang-Chi Chen
IPC分类号: C07D471/02
CPC分类号: C07D471/04
摘要: A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds can be useful as factor Xa inhibitors.
摘要翻译: 描述了由合适的苯肼制备下列所示类型的4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的新方法及其中间体。
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8.Process for preparing 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones 有权
标题翻译: 制备4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的方法公开(公告)号:US07396932B2
公开(公告)日:2008-07-08
申请号:US11235510
申请日:2005-09-26
申请人: Rafael Shapiro , Lucius T Rossano , Boguslaw M Mudryk , Nicolas Cuniere , Matthew Oberholzer , Huiping Zhang , Bang-Chi Chen
发明人: Rafael Shapiro , Lucius T Rossano , Boguslaw M Mudryk , Nicolas Cuniere , Matthew Oberholzer , Huiping Zhang , Bang-Chi Chen
IPC分类号: C07D471/02 , C07D491/02 , C07D498/02 , C07D513/02 , C07D515/02
CPC分类号: C07D471/04
摘要: A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds can be useful as factor Xa inhibitors.
摘要翻译: 描述了由合适的苯肼制备下列所示类型的4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的新方法及其中间体。 这些化合物可用作因子Xa抑制剂。
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公开(公告)号:US07598380B2
公开(公告)日:2009-10-06
申请号:US11492750
申请日:2006-07-25
申请人: Wansheng Liu , Sunil S. Patel , Nicolas Cuniere , Yvonne Lear , Prashant P. Deshpande , Jeffrey N. Simon , Chiajen Lai , Annie J. Pullockaran , Nachimuthu Soundararajan , Jeffrey T. Bien
发明人: Wansheng Liu , Sunil S. Patel , Nicolas Cuniere , Yvonne Lear , Prashant P. Deshpande , Jeffrey N. Simon , Chiajen Lai , Annie J. Pullockaran , Nachimuthu Soundararajan , Jeffrey T. Bien
IPC分类号: C07D487/04 , C07D213/69 , C07D213/73
CPC分类号: C07D213/73 , C07D213/69 , C07D471/04
摘要: A method of preparing azaindole compounds for antiviral use having the formula
摘要翻译: 制备具有下式的用于抗病毒用途的唑烷醇化合物的方法
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公开(公告)号:US20090312549A1
公开(公告)日:2009-12-17
申请号:US12546108
申请日:2009-08-24
申请人: WANSHENG LIU , Sunil S. Patel , Nicolas Cuniere , Yvonne Lear , Prashant P. Deshpande , Jeffrey N. Simon , Chiajen Lai , Annie J. Pullockaran , Nachimuthu Soundararajan , Jeffrey T. Bien
发明人: WANSHENG LIU , Sunil S. Patel , Nicolas Cuniere , Yvonne Lear , Prashant P. Deshpande , Jeffrey N. Simon , Chiajen Lai , Annie J. Pullockaran , Nachimuthu Soundararajan , Jeffrey T. Bien
IPC分类号: C07D471/04
CPC分类号: C07D213/73 , C07D213/69 , C07D471/04
摘要: A method of preparing azaindole compounds for antiviral use having the formula
摘要翻译: 制备具有下式的用于抗病毒用途的唑烷醇化合物的方法
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