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公开(公告)号：US20080161226A1
公开(公告)日：2008-07-03
申请号：US11845167
申请日：2007-08-27
申请人： Lance E. Steward , Joseph Francis , Ester Fernandez-Salas , Marcella A. Gilmore , Shengwen Li , J. Oliver Dolly , Kei Roger Aoki
发明人： Lance E. Steward , Joseph Francis , Ester Fernandez-Salas , Marcella A. Gilmore , Shengwen Li , J. Oliver Dolly , Kei Roger Aoki
CPC分类号： C07K14/33 , A61K38/00 , C12N9/52 , Y02A50/469
摘要： Compositions comprising activatable recombinant neurotoxins and polypeptides derived therefrom. The invention also comprises nucleic acids encoding such polypeptides, and methods of making such polypeptides and nucleic acids.
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公开(公告)号：US08273358B2
公开(公告)日：2012-09-25
申请号：US12192900
申请日：2008-08-15
申请人： Lance E. Steward , Joseph Francis , Ester Fernandez-Salas , Sanjiv Ghanshani , Marcella A. Gilmore , Shengwen Li , J. Oliver Dolly , Kei Roger Aoki
发明人： Lance E. Steward , Joseph Francis , Ester Fernandez-Salas , Sanjiv Ghanshani , Marcella A. Gilmore , Shengwen Li , J. Oliver Dolly , Kei Roger Aoki
CPC分类号： C07K14/33 , A61K38/00 , C12N9/52 , Y02A50/469
摘要： Compositions comprising activatable recombinant neurotoxins and polypeptides derived therefrom. The invention also comprises nucleic acids encoding such polypeptides, and methods of making such polypeptides and nucleic acids.
摘要翻译： 包含可活化的重组神经毒素和由其衍生的多肽的组合物。 本发明还包括编码这种多肽的核酸，以及制备这种多肽和核酸的方法。
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公开(公告)号：US08211671B2
公开(公告)日：2012-07-03
申请号：US12177415
申请日：2008-07-22
申请人： J. Oliver Dolly , Yan Li , Kuo Chion Chan
发明人： J. Oliver Dolly , Yan Li , Kuo Chion Chan
CPC分类号： C07K14/33 , A61K38/00 , C12N9/52 , Y02A50/469
摘要： Compositions comprising activatable recombinant neurotoxins and polypeptides derived therefrom. The invention also comprises nucleic acids encoding such polypeptides, and methods of making such polypeptides and nucleic acids.
摘要翻译： 包含可活化的重组神经毒素和由其衍生的多肽的组合物。 本发明还包括编码这种多肽的核酸，以及制备这种多肽和核酸的方法。
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公开(公告)号：US07740868B2
公开(公告)日：2010-06-22
申请号：US11832173
申请日：2007-08-01
申请人： Lance E. Steward , Joseph Francis , Ester Fernandez-Salas , Sanjiv Ghanshani , Marcella A. Gilmore , Shengwen Li , J. Oliver Dolly , Kei Roger Aoki
发明人： Lance E. Steward , Joseph Francis , Ester Fernandez-Salas , Sanjiv Ghanshani , Marcella A. Gilmore , Shengwen Li , J. Oliver Dolly , Kei Roger Aoki
CPC分类号： C07K1/22 , C07K14/33 , C07K14/68 , C07K14/695 , C12N9/52
摘要： Compositions comprising activatable recombinant neurotoxins and polypeptides derived therefrom. The invention also comprises nucleic acids encoding such polypeptides, and methods of making such polypeptides and nucleic acids.
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公开(公告)号：US07709228B2
公开(公告)日：2010-05-04
申请号：US11782112
申请日：2007-07-24
申请人： J. Oliver Dolly , Yan Li , Kuo Chion Chan
发明人： J. Oliver Dolly , Yan Li , Kuo Chion Chan
CPC分类号： C07K14/33 , A61K38/00 , C12N9/52 , Y02A50/469
摘要： Compositions comprising activatable recombinant neurotoxins and polypeptides derived therefrom. The invention also comprises nucleic acids encoding such polypeptides, and methods of making such polypeptides and nucleic acids.
摘要翻译： 包含可活化的重组神经毒素和由其衍生的多肽的组合物。 本发明还包括编码这种多肽的核酸，以及制备这种多肽和核酸的方法。
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公开(公告)号：US20090004224A1
公开(公告)日：2009-01-01
申请号：US12192546
申请日：2008-08-15
申请人： Lance E. Steward , Jospeh Francis , Ester Fernandez-Salas , Marcella A. Gilmore , Shengwen Li , J. Oliver Dolly , Kei Roger Aoki
发明人： Lance E. Steward , Jospeh Francis , Ester Fernandez-Salas , Marcella A. Gilmore , Shengwen Li , J. Oliver Dolly , Kei Roger Aoki
CPC分类号： C07K14/33 , A61K38/00 , C12N9/52 , Y02A50/469
摘要： Compositions comprising activatable recombinant neurotoxins and polypeptides derived therefrom. The invention also comprises nucleic acids encoding such polypeptides, and methods of making such polypeptides and nucleic acids.
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公开(公告)号：US07419676B2
公开(公告)日：2008-09-02
申请号：US11326265
申请日：2006-01-05
申请人： J. Oliver Dolly , Yan Li , Kuo Chion Chan
发明人： J. Oliver Dolly , Yan Li , Kuo Chion Chan
CPC分类号： C07K14/33 , A61K38/00 , C12N9/52 , Y02A50/469
摘要： Compositions comprising activatable recombinant neurotoxins and polypeptides derived therefrom. The invention also comprises nucleic acids encoding such polypeptides, and methods of making such polypeptides and nucleic acids.
摘要翻译： 包含可活化的重组神经毒素和由其衍生的多肽的组合物。 本发明还包括编码这种多肽的核酸，以及制备这种多肽和核酸的方法。
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