公开(公告)号：US20190194279A1

公开(公告)日：2019-06-27

申请号：US16329800

申请日：2017-09-04

Applicant: James Cook University

Inventor： Alex Loukas ,  Michael Smout ,  Norelle Daly

IPC: C07K14/475 ,  A61P17/02

CPC classification number: C07K14/475 ,  A61K38/00 ,  A61P17/02 ,  A61P43/00

Abstract: Peptides derived from the N-terminal region of granulin have activity in promoting cell proliferation, migration and/or wound healing. Furthermore, an additional disulphide bond may be engineered into such peptides to improve or otherwise modify the folding of the peptide. The peptides may also be modified such as at proline residues improve the ability of the peptide to promote cell proliferation.

公开(公告)号：US20190174793A1

公开(公告)日：2019-06-13

申请号：US16321070

申请日：2016-07-29

Applicant: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION ,  MEAT & LIVESTOCK AUSTRALIA LIMITED ,  JAMES COOK UNIVERSITY

Inventor： Nigel William TOMKINS ,  Rocky DE NYS ,  Robert Douglas KINLEY ,  Marie Elisabeth MAGNUSSON ,  Lorenna MACHADO ,  Nicholas Andrew PAUL

IPC: A23K10/30 ,  A23K50/10 ,  A23K40/20

Abstract: The invention relates to utilising red marine macroalgae to provide improvements in growth performance of livestock, particularly ruminant animals for red meat production, especially cattle, in pasture and feedlot farming systems. There is provided a method for improving the growth performance of a livestock animal in a farming system including: providing a red marine macroalgae to a farming system to enable consumption of the red marine macroalgae by a livestock animal in the farming system; thereby improving the growth performance of the livestock animal in the system.

公开(公告)号：US09637527B2

公开(公告)日：2017-05-02

申请号：US14384681

申请日：2013-03-13

Applicant: JAMES COOK UNIVERSITY

Inventor： Alex Loukas ,  Severine Navarro

IPC: C07K14/435 ,  A61K38/57 ,  A61K39/00 ,  A61K45/06

CPC classification number: C07K14/4354 ,  A61K38/57 ,  A61K39/0003 ,  A61K45/06

Abstract: A method for reducing or alleviating inflammation in a subject includes administering to the subject a therapeutically effective amount of: (a) Ac-TMP-1 or a biologically active fragment or variant of Ac-TMP-1; (b) Ac-TMP-2 or a biologically active fragment or variant of Ac-TMP-2; or (c) a combination of (a) and (b), to thereby reduce or alleviate inflammation in the subject. A method for preventing or treating asthma or inflammatory bowel disease in a subject includes administering to the subject a therapeutically effective amount of: (a) Ac-TMP-1 or a biologically active fragment or variant of Ac-TMP-1; (b) Ac-TMP-2 or a biologically active fragment or variant of Ac-TMP-2; or (c) a combination of (a) and (b), to thereby prevent or treat asthma or inflammatory bowel disease in the subject. The subject may be a mammal, inclusive of humans.