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公开(公告)号：US11273425B2
公开(公告)日：2022-03-15
申请号：US17034903
申请日：2020-09-28
Applicant: HYUNDAI MOTOR COMPANY , KIA MOTORS CORPORATION , Kookmin University Industry Academy Cooperation Foundation
Inventor： Dong Hoon Nam , Kyung Moon Lee , Hoon Mo Park , Young-Jin Cho , Byeong Soo Shin , Hee Joon Lee , Seon Jeong Huh
Abstract: A dehydrogenation chemical reactor includes: a housing; a catalyst part made of a thermally conductive material and disposed in the housing, where the catalyst part has a panel shape, and a catalyst is coated on a surface of the catalyst part to separate hydrogen from an organic hydrogen carrier; a heat transfer pipe which is installed to contact the catalyst part, and conducts latent heat to the catalyst part while pressurized and saturated fluid is supplied therein; and an organic hydrogen carrier line which is connected to the housing to form a passage in which the organic hydrogen carrier is introduced into the housing, contacts the catalyst part to separate hydrogen, and then is discharged.
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公开(公告)号：US11255752B2
公开(公告)日：2022-02-22
申请号：US16839933
申请日：2020-04-03
Applicant: HYUNDAI MOTOR COMPANY , KIA MOTORS CORPORATION , Kookmin University Industry Academy Cooperation Foundation
Inventor： Jae-Min Jin , In-Soo Jung , Sung-Hwan Shin
Abstract: A mechanical diagnosis method for combustion abnormality using engine noise includes: calculating an Energy K and a Loudness standard deviation index (NSTD) with Kurtosis analysis by a diagnosis controller 30 from noise data measured together with a signal component by rotation excitation of an engine 10; calculating a plurality of order frequency peak order component values by a Modulation Frequency Transform; and distinguishing a cylinder where abnormal combustion occurs from a cylinder where normal combustion occurs by applying a predetermined threshold to these calculated values, thereby classifying, by Modulation Frequency analysis, problem samples of the rotation excitation and combustion excitation influence of the engine in which the abnormality state determination of the engine has been difficult only with energy distribution while overcoming the limitation of Kurtosis analysis.
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公开(公告)号：US20220017971A1
公开(公告)日：2022-01-20
申请号：US17375009
申请日：2021-07-14
Inventor： Whasun Lim , Gwonhwa Song , Hee Seung Kim
IPC: C12Q1/6886 , A61K33/243 , A61K31/337 , C12N15/113
Abstract: The present invention relates to a composition for predicting resistance to chemotherapy for ovarian cancer and uses thereof, and more particularly, as the expression of exosome-derived miR-214-3p in epithelial ovarian cancer patients increases, the expression of the target gene LHX6 is suppressed, malignancy of epithelial ovarian cancer and anticancer drug resistance are increased, the change in the expression level of miR-214-3p and LHX6 can be provided as a composition for predicting the prognosis of cancer malignancy and anticancer drug resistance in epithelial ovarian cancer patients, and as it was confirmed that apoptosis of epithelial ovarian cancer cells treated with miR-214-3p inhibitors increases and the anticancer drug resistance is regulated by the expression regulation of miR-214-3p and LHX6, the miR-214-3p inhibitor and the activator or expression promoter of LHX6 may be provided as an anti-cancer therapeutic agent or an anti-cancer drug sensitizer for epithelial ovarian cancer cells.
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公开(公告)号：US11130126B2
公开(公告)日：2021-09-28
申请号：US16521402
申请日：2019-07-24
Inventor： Si Hyung Lim , Jang Hyeon Lee , Yeong Seok Lee , Ae Ran Song
IPC: B01L3/00 , G01N27/403
Abstract: There is provided a fluid analysis chamber module that allows an analysis element to be replaced in a sliding manner. The module includes a middle body, an upper body, and a lower body, in which the upper body and the lower body are rotated to be in contact with an upper surface and a lower surface of the middle body and to release from the contact state. The middle body provides a chamber hole where a tray with the analysis element seated thereon can be mounted. The middle body is provided on its front end with a tray receiving opening through which the tray is mounted into the chamber hole. When the upper body and lower body are rotated to be in contact with the upper surface and the lower surface, respectively, the chamber hole is closed, a fluid supplying line and discharging line are sealed, pogo pins for power supply and signal transmission are contacted to electrodes of the analysis element.
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公开(公告)号：US20210245144A1
公开(公告)日：2021-08-12
申请号：US17236665
申请日：2021-04-21
Inventor： Sungho Yoon , Senkuttuvan Rajendiran , Jianwei Jiang , Kwang Ho Park
IPC: B01J31/16 , B01J37/00 , C07D305/12 , C07D307/60
Abstract: A transition metal-based heterogeneous carbonylation reaction catalyst has an excellent catalytic activity and selectivity in the carbonylation reaction and is easily separated from a product, by crosslinking polymerizing a transition metal-based homogeneous catalyst unit through a Friedel-Craft reaction. The catalyst may be used in a method for preparing lactone. The transition metal-based heterogeneous carbonylation reaction catalyst allows to produce lactone or succinic anhydride with an epoxide compound while showing a high selectivity, and can be applied in industrial very usefully due to easy separation from the product and thus reusing thereof.
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Patent Agency Ranking
公开(公告)号：US20210057989A1
公开(公告)日：2021-02-25
申请号：US16997475
申请日：2020-08-19
Applicant: Samsung Electronics Co., Ltd. , Kookmin University Industry Academy Cooperation Foundation
Inventor： Duhee JANG , Sangkyoo HAN , Jeongil KANG , Kasan HA , Sanghoon LEE
Abstract: Disclosed are a display apparatus and an electronic apparatus, the display apparatus including: a main body including a display and a connector; and an adapter connectable to the main body and configured to supply power to the connected main body, the adapter including: a transformer configured to boost an input first alternating current (AC) voltage, a switch including a switching device configured to switch a current flowing in the transformer, a controller configured to control the switching device to output a second AC voltage boosted by the transformer, and the main body including a power factor correction (PFC) converter configured to correct a power factor of the second AC voltage output from the adapter and output a direct current (DC) voltage.
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公开(公告)号：US20200332290A1
公开(公告)日：2020-10-22
申请号：US16631954
申请日：2018-07-17
Inventor： Hyunjeong LIEW
IPC: C12N15/113 , C12Q1/6883 , A61P25/28 , A61K9/00
Abstract: The present invention relates to a method for providing information on the diagnosis of Parkinson's disease. The present invention also relates to a composition for preventing, ameliorating or treating Parkinson's disease. The present invention uses at least one miRNA whose expression is specifically down- or up-regulated in a Parkinson's disease model. Therefore, the use of the miRNA is effective in diagnosing and treating Parkinson's disease.
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公开(公告)号：US20200230346A1
公开(公告)日：2020-07-23
申请号：US16525183
申请日：2019-07-29
Inventor： Hyun Sun Mo , Young Rag Do , Dae Jeong Kim , Dae Hwan Kim , Sung Yeon Jang , In Hwan Jung , Dong Myung Kim , Seong Jin Choi , Sanggyu Yim , Hyung Min Kim , Sun Woong Choi , Gu Min Jeong , Seung Min Lee
IPC: A61M21/02
Abstract: Disclosed are an apparatus and a system for managing circadian rhythm. The apparatus includes an illuminance measuring portion which measures a bio illuminance value of external light using a circadian lambda filter which passes the external light along according to a circadian rhythm sensitivity curve and a visual lambda filter which passes the external light along according to a visual sensitivity curve, a controller which outputs a control signal for reinforcing a user's circadian rhythm on the basis of the bio illuminance value, and a circadian rhythm reinforcing portion which emits light of a circadian wavelength band toward the user according to the control signal.
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公开(公告)号：US20200223938A1
公开(公告)日：2020-07-16
申请号：US16603273
申请日：2018-04-06
Applicant: KOOKMIN UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION , OSONG MEDICAL INNOVATION FOUNDATION
Inventor： Sang Taek JUNG , Sanghwan KO , Tae Gyu LEE , So Young CHOI , Soo Han LEE , Myung Ho SOHN , Su Jin KIM , So Ra PARK , Jong Shik PARK , Ju Hyeon LIM
IPC: C07K16/32
Abstract: The present invention relates to a polypeptide including an Fc variant produced by substituting a portion of the amino acid sequence of the Fc domain of a human antibody with a different amino acid sequence. The present invention also relates to an antibody including the polypeptide. The Fc variant can find application in a wide range of antibodies and Fc-fusion constructs. In one aspect, the antibody or Fc fusion construct of the present invention is a therapeutic, diagnostic or laboratory reagent, preferably a therapeutic reagent. The Fc variant is suitable for use in the treatment of cancer because its in vivo half-life can be maximized by optimization of the portion of the amino acid sequence. The antibody or Fc fusion construct of the present invention is used to kill target cells that bear a target antigen, for example cancer cells. Alternatively, the antibody or Fc fusion construct of the present invention is used to block, antagonize or agonize a target antigen. For example, the antibody or Fc fusion construct of the present invention may be used to antagonize a cytokine or a cytokine receptor.
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公开(公告)号：US20200078338A1
公开(公告)日：2020-03-12
申请号：US16686940
申请日：2019-11-18
Inventor： Sangtaek OH
IPC: A61K31/4184 , A61K9/00 , A61K31/015 , A61K9/06 , A23L33/10 , A61P27/02 , A61K31/122 , A61K31/136 , A61K31/145 , A61K31/196 , A61K31/235
Abstract: The present disclosure relates to a novel use of a sesquiterpene derivative, more particularly to a composition for preventing, improving or treating macular degeneration or macular edema caused by vascular leakage in the eye, the composition containing a sesquiterpene derivative compound represented by Chemical Formula 1 of the present disclosure or a pharmaceutically acceptable salt thereof as an active ingredient. Whereas the intraocular disease-related treating agents available in the market should be injected directly into the vitreous cavity, thus causing pain and side effects, the sesquiterpene derivative compound of the present disclosure is delivered to the target tissue (eye) via different administration routes (oral, intraperitoneal, etc.) other than the intravitreal route. Accordingly, the sesquiterpene derivative compound provides excellent therapeutic effect without being restricted by the administration routes.
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