公开(公告)号：USRE43005E1

公开(公告)日：2011-12-06

申请号：US11943867

申请日：2007-11-21

Applicant: Bo Lin Zheng ,  Kan He ,  Yu Shao ,  Qun Yi Zheng

Inventor： Bo Lin Zheng ,  Kan He ,  Yu Shao ,  Qun Yi Zheng

IPC: C07C231/00 ,  C07C233/00 ,  A01N65/00

CPC classification number: A61K36/31

Abstract: The invention relates to compositions that can be isolated from Lepidium plant material and to methods for their isolation. The compositions are useful for treating and preventing cancer and sexual dysfunction.

Abstract translation: 本发明涉及可从Lepidium植物材料中分离的组合物及其分离方法。 该组合物可用于治疗和预防癌症和性功能障碍。

公开(公告)号：US20100278944A1

公开(公告)日：2010-11-04

申请号：US12435343

申请日：2009-05-04

Applicant: Andrew Scholey ,  Alvin Ibarra ,  Kan He ,  Marc Roller ,  Jacques Dikansky

Inventor： Andrew Scholey ,  Alvin Ibarra ,  Kan He ,  Marc Roller ,  Jacques Dikansky

IPC: A61K36/258 ,  A61P25/28

CPC classification number: A61K36/258

Abstract: Disclosed are methods of enhancing neurocognitive function by administering of American Ginseng. Preferred dosages in the range of 5 to 50 mg total genosides enhance cognitive function—including, improvement of working memory (WM) performance, attentional performance (e.g., Choice Reaction Time accuracy), and calmness.

Abstract translation: 公开的是通过施用美国人参来增强神经认知功能的方法。 优选的剂量范围为5至50mg的总苷类增强了认知功能，包括改善工作记忆（WM）性能，注意性能（例如，选择反应时间精度）和平静度。

公开(公告)号：US20100123718A1

公开(公告)日：2010-05-20

申请号：US12273202

申请日：2008-11-18

Applicant: Kan He

Inventor： Kan He

IPC: G06T11/20

CPC classification number: G06T11/206

Abstract: Methods and systems for boundary delineation are described. In one embodiment, a living unit identifier may be translated into a translated geographic location point. The living unit identifier may be within a distribution area. A closed plane living unit-based figure that bounds the translated geographic location point may be delineated. An additional closed plane living unit-based figure that bounds a geographic location point may be delineated. The geographic location point may be associated with an additional living unit identifier within the distribution area. The closed plane living unit-based figure and the additional closed plane living unit-based figure may be merged to create a distribution area figure of the distribution area. Additional methods and systems are disclosed.

Abstract translation: 描述了边界描绘的方法和系统。 在一个实施例中，生物单元标识符可以被翻译成翻译的地理位置点。 生活单元标识符可以在分配区域内。 可以划定限制翻译的地理位置点的封闭平面生活单位数字。 可以划定限制地理位置点的附加的基于平面的生活单位数字。 地理位置点可以与分配区域内的附加生命单元标识符相关联。 可以合并封闭平面生活单位数字和附加闭路平面生活单位数字，形成分布区域的分布区域图。 公开了附加的方法和系统。

公开(公告)号：US06428824B1

公开(公告)日：2002-08-06

申请号：US10002757

申请日：2001-10-19

Applicant: Bo Lin Zheng ,  Calvin Hyungchan Kim ,  Stephen Wolthoff ,  Kan He ,  Lingling Rogers ,  Yu Shao ,  Qun Yi Zheng

Inventor： Bo Lin Zheng ,  Calvin Hyungchan Kim ,  Stephen Wolthoff ,  Kan He ,  Lingling Rogers ,  Yu Shao ,  Qun Yi Zheng

IPC: A61K3578

CPC classification number: A61K36/31

Abstract: An isolated composition obtained by extracting Lepidium meyenii roots is provided. The composition is substantially free of cellulose and comprises between about 5% and about 9% of benzyl isothiocyanate, between about 1% and about 3% of Lepidium sterol component, between about 20% and about 30% of Lepidium fatty acid component, and about 10% or more of macamide component. The composition is prepared by a process which comprises contacting Lepidium meyenii roots with a first aqueous solvent of about 90% vol-% or more water, then separating the residual Lepidium meyenii root material from the first contacted aqueous solvent, then contacting the residual Lepidium meyenii root material with a second aqueous solvent which comprises a mixture of an alcohol and water having about 90 vol-% alcohol or more to form a liquor, and then finally concentrating the liquor to obtain the composition. The composition can be used for treating cancer and sexual dysfunction.

Abstract translation: 提供了通过提取梅毒根获得的分离组合物。 所述组合物基本上不含纤维素，并且包含约5％至约9％的异硫氰酸苄酯，约1％至约3％的Lepidium sterol组分，约20％至约30％的Lepidium脂肪酸组分和约 10％以上的macamide成分。 组合物通过以下方法制备，该方法包括使梅毒根与约90％体积％或更多的水的第一含水溶剂接触，然后从残留的第一次接触的水性溶剂中分离剩余的梅毒根部物质，然后将剩余的梅毒 根部材料与第二含水溶剂组成，其包含具有约90体积％醇或更多醇的醇和水的混合物以形成液体，然后最终将液体浓缩以获得组合物。 该组合物可用于治疗癌症和性功能障碍。

公开(公告)号：US20090117214A1

公开(公告)日：2009-05-07

申请号：US12185649

申请日：2008-08-04

Applicant: Kan He ,  Marc Roller ,  Antonie Bily ,  Naisheng Bai ,  Jacques Dikansky ,  Alvin Ibarra

Inventor： Kan He ,  Marc Roller ,  Antonie Bily ,  Naisheng Bai ,  Jacques Dikansky ,  Alvin Ibarra

IPC: A61K36/63 ,  A61K31/7088 ,  A61P3/00 ,  C07G3/00

CPC classification number: A61K36/63 ,  A61K31/7088

Abstract: A Fraxinus excelsior seed extract that can be administered for therapeutic treatment of a subject, including a human, by blocking fat synthesis, activating PPAR-alpha, increasing hypoglycemic activity, reducing bodyweight, controlling fasting plasma insulin levels against hyperinsulinemia, and promoting insulin sensitivity and causing a beneficial acute insulinotropic effect. The Fraxinus excelsior seed extract includes, inter alia, an isolated compound (2S,3E,4S) 2H-Pyran-4-acetic acid-3-ethylidene-2-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl) oxy]-3,4-dihydro-5-(methoxycarbonyl)methyl ester, commonly called excelside A, an isolated compound (2S,3E,4S) 2H-Pyran-4-acetic acid-3-ethylidene-2-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-3,4-dihydro-5-(methoxycarbonyl) 2-(4-hydroxyphenyl)ethyl ester, commonly called excelside B, and the compounds G15, G13, nuzhenide, and oleoside dimethyl ester.

Abstract translation: 可以通过阻断脂肪合成，激活PPAR-α，增加降血糖活性，降低体重，控制空腹血浆胰岛素水平与高胰岛素血症的关系，以及促进胰岛素敏感性以及促进胰岛素敏感性的方法，将可以用于治疗受试者（包括人）的Fraxinus excelsior种子提取物 引起有益的急性促胰岛素作用。 Fraxinus excelsior种子提取物尤其包括分离的化合物（2S，3E，4S）2H-吡喃-4-乙酸-3-亚乙基-2 - [（6-O-β-D-吡喃葡萄糖基-β-D - 吡喃葡萄糖基）氧基] -3,4-二氢-5-（甲氧基羰基）甲酯，通常称为excelside A，分离的化合物（2S，3E，4S）2H-吡喃-4-乙酸-3-亚乙基-2- 氧基] -3,4-二氢-5-（甲氧基羰基）-2-（4-羟基苯基）乙酯（通常称为excelside B）的化合物和化合物（6-O-β-D-吡喃葡萄糖基-β-D-吡喃葡萄糖基） G15，G13，nunzhenide和油脂二甲酯。

公开(公告)号：US20070116786A1

公开(公告)日：2007-05-24

申请号：US11460142

申请日：2006-07-26

Applicant: Qun Zheng ,  Bo Zheng ,  Kan He

Inventor： Qun Zheng ,  Bo Zheng ,  Kan He

IPC: A61K36/185 ,  A61K31/56 ,  A61K31/198 ,  A61K31/26 ,  A61K31/165

CPC classification number: A61K36/31 ,  A61K31/165 ,  A61K31/198 ,  A61K31/26 ,  A61K31/56 ,  A61K2300/00

Abstract: The present invention relates to compositions containing particular components that can be obtained from a plant which can have pharmaceutical applications. More particularly, the plant genus is Lepidium and the composition may contain in the range of between about 0.3% and 0.7% of benzyl isothiocyanate, b) between about 0.06% and about 0.02% of Lepidium sterol component, c) between about 1% and about 2% of a Lepidium fatty acid component, and d) about 0.006% to 0.6% or more total macamide/macaenes component as standardized with excipients.

Abstract translation: 本发明涉及包含可以从可以具有药物应用的植物获得的特定组分的组合物。 更具体地，植物属是叶菜属，组合物可以含有约0.3％至0.7％的异硫氰酸苄酯，b）约0.06％至约0.02％的Lepidium甾醇组分，c）约1％至 约2％的Lepidium脂肪酸组分，以及d）用赋形剂标准化的约0.006％至0.6％或更多的总的macamide / macaenes组分。