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    NON-STEROIDAL TOPICAL COMPOSITION AND METHOD THEREOF
    4.
    发明公开
    NON-STEROIDAL TOPICAL COMPOSITION AND METHOD THEREOF 审中-公开

    公开(公告)号：US20240216455A1

    公开(公告)日：2024-07-04

    申请号：US17916806

    申请日：2021-07-23

    申请人： ANUPAM GUPTA

    发明人： ANUPAM GUPTA

    IPC分类号： A61K36/31 ,  A61K9/00 ,  A61K33/04 ,  A61K33/14 ,  A61K33/42 ,  A61K36/54 ,  A61K36/9066

    CPC分类号： A61K36/31 ,  A61K9/0014 ,  A61K33/04 ,  A61K33/14 ,  A61K33/42 ,  A61K36/54 ,  A61K36/9066

    摘要： The embodiments relate to a non-steroidal topical formulation comprising 10 wt % to 20 wt % of an active ingredient consisting of a combination of group I and group II component and 80 wt % to 90 wt % of inactive ingredient comprising one or more pharmaceutically acceptable excipient. The group I component maybe a plant extract obtained from Curcuma spp, Litsea spp., and Lepidium spp. and group II component may be selected from a group comprising Potassium sulfate (Kali sulphuricum), Potassium Phosphate (Kali phosphoricum), Sodium sulfate (Natrum sulphuricum, Sodium chloride (Natrum phosphoricum), Potassium Chloride (Kali muriaticum), and Sodium Phosphate (Natrum phosphoricum). The said formulation is capable of efficiently eliminating or reducing age-related osteoarthritic joint pain, inflammation and musculoskeletal diseases and provides long-term relief to the aged patients. Another preferred embodiment of the present invention relates to a method of preparing the said formulation.

    Method of making gold nanoparticles capped with
    9.
    发明授权
    Method of making gold nanoparticles capped with 有权

    公开(公告)号：US11938151B1

    公开(公告)日：2024-03-26

    申请号：US18519662

    申请日：2023-11-27

    申请人： KING FAISAL UNIVERSITY

    发明人： Enas Mohamed Ali ,  Basem Mohamed Abdallah ,  Peramaiyan B. Rajendran

    IPC分类号： A61K33/242 ,  A61K36/31 ,  B82Y5/00

    CPC分类号： A61K33/242 ,  A61K36/31 ,  B82Y5/00

    摘要： In order to inhibit the growth of fungi, such as Madurella mycetomatis, gold nanoparticles are synthesized and capped with an extract of Reseda arabica. The gold nanoparticles capped with the extract of Reseda arabica are made by adding the extract of Reseda arabica to an aqueous sodium tetrachloroaurate (NaAuCl4) solution to reduce the sodium tetrachloroaurate and form a suspension of gold nanoparticles capped with the extract of Reseda arabica. The extract of Reseda arabica acts as a reducing and stabilizing agent while also functionalizing the surfaces of the gold nanoparticles to cap the surfaces. The suspension may be boiled, followed by removal of the gold nanoparticles capped with the extract of Reseda arabica from the suspension. To treat a Madurella mycetomatis infection, an effective dose of the gold nanoparticles capped with Reseda arabica extract may be administered to a patient in need thereof.