公开(公告)号：US20230285923A1

公开(公告)日：2023-09-14

申请号：US18006650

申请日：2021-07-28

Applicant: MORISHITA JINTAN CO., LTD.

Inventor： Takehiro NISHIKAWA ,  Taku HASHIMOTO ,  Hideo SUGIMOTO ,  Ai NISHIBAYASHI

IPC: B01J13/16

CPC classification number: B01J13/16

Abstract: The present invention easily provides microcapsules by using a production method according to a more efficient and reliable interfacial polymerization method even when it is difficult to produce microcapsules by an interfacial polymerization method by adding a solution of a film-forming substance. Specifically, the present invention provides a method for producing microcapsules using two types of emulsion particles differing in size, the method comprising:



an emulsion-forming step of separately forming two types of emulsions (1) and (2) whose continuous phases are common, wherein emulsion particles (1) of the emulsion (1) comprises one of two types of monomers which react with each other to form a film and emulsion particles (2) of the emulsion (2) comprises the other monomer; and
a microcapsule-forming step of mixing and interfacial-polymerizing the emulsion (1) and the emulsion (2),
wherein
the emulsion particles (1) of the emulsion (1) have an average particle size (R) of 0.1 to 300 μm,
the emulsion particles (2) of the emulsion (2) have an average particle size (r) of 0.01 to 30 μm, and
r/R≤0.1 is satisfied.

公开(公告)号：US20220226252A1

公开(公告)日：2022-07-21

申请号：US17595908

申请日：2020-06-12

Applicant: MORISHITA JINTAN CO., LTD.

Inventor： Takehiro NISHIKAWA ,  Katsutoshi ISHII ,  Kazuma TAKAHASHI

IPC: A61K9/48 ,  A61K31/375 ,  A61K35/744 ,  A61K31/19

Abstract: An object of the present invention is to provide a technique for delaying disintegration of a capsule by blending a certain component in a core of the capsule, and to increase the degree of freedom in capsule design. The present invention relates to a delayed disintegration-type seamless capsule that is a seamless capsule including a core, one or more intermediate layers formed on the core, and an outermost layer formed on the intermediate layers, wherein the core contains an active substance, an amphoteric surfactant, and a fat having a melting point of 40° C. or more, at least one layer of the intermediate layers contains a fat having a melting point of 45° C. or more, and the outermost layer contains a water-soluble natural polymer. The present invention also relates to a method for producing the same.

公开(公告)号：US20150190448A1

公开(公告)日：2015-07-09

申请号：US14378895

申请日：2013-02-15

Applicant: MORISHITA JINTAN CO., LTD

Inventor： Tatsuya Ohara ,  Koutarou Muroyama ,  Shinji Murosaki ,  Yoshihiro Yamamoto

IPC: A61K36/738 ,  A61K31/7048 ,  A23L1/30 ,  A61K31/522

CPC classification number: A61K36/738 ,  A23K10/30 ,  A23K20/10 ,  A23K20/111 ,  A23L2/52 ,  A23L33/10 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/522 ,  A61K31/7048 ,  A61K2300/00

Abstract: A primary object of the invention is to provide a composition for the prevention, amelioration, or treatment of metabolic syndrome and to provide a food or drink, a medicine, or a feed comprising the composition. A composition for the prevention, amelioration, or treatment of metabolic syndrome, the composition comprising the following (a) and (b):(a) a rose hip extract, and (b) at least a kind of xanthine derivatives.

Abstract translation: 本发明的主要目的是提供一种用于预防，改善或治疗代谢综合征的组合物，并提供包含该组合物的食物或饮料，药物或饲料。 用于预防，改善或治疗代谢综合征的组合物，所述组合物包含以下（a）和（b）：（a）玫瑰果提取物，和（b）至少一种黄嘌呤衍生物。

公开(公告)号：US20130259933A1

公开(公告)日：2013-10-03

申请号：US13652543

申请日：2012-10-16

Applicant: MORISHITA JINTAN CO., LTD.

Inventor： Ryosei KAMAGUCHI ,  Masafumi MIZUTANI

IPC: A61K9/48 ,  B01J13/02 ,  A61K38/40 ,  A61K38/48 ,  A61K38/02 ,  A61K35/74

CPC classification number: A61K9/4808 ,  A61K9/4816 ,  A61K35/745 ,  A61K35/747 ,  A61K38/40 ,  A61K38/482 ,  C12Y304/21062

Abstract: The present invention is to obtain capsules which do not disintegrate in stomach and intestine after orally administrating them and which disintegrate specifically in large intestine.The present invention thus provides a capsule which disintegrates specifically in large intestine, comprising a content comprising a main agent, and a shell, covering the content, comprising a natural water-soluble polymer as a shell base material and chitosan powder dispersing in the natural water-soluble polymer.

Abstract translation: 本发明是为了获得在口服给药后不在胃和肠中分解的胶囊，特别是在大肠中分解。 因此，本发明提供了一种特别在大肠中分解的胶囊，其包含包含主剂和包覆内容物的壳的内容物，其包含作为壳基质的天然水溶性聚合物和分散在天然水中的壳聚糖粉末 可溶性聚合物。