Substituted tetracycline compounds for the treatment of malaria
    24.
    发明授权
    Substituted tetracycline compounds for the treatment of malaria 有权
    用于治疗疟疾的取代四环素化合物

    公开(公告)号:US08088820B2

    公开(公告)日:2012-01-03

    申请号:US10692563

    申请日:2003-10-24

    Abstract: This invention provides a method for treating or preventing malaria in a subject. The method includes administering to the subject an effective amount of a substituted tetracycline compound, such that malaria is treated or prevented. In one aspect, the invention relates to pharmaceutical compositions which include an effective amount of a tetracycline compound to treat malaria in a subject and a pharmaceutically acceptable carrier. The substituted tetracycline compounds of the invention can be used to in combination with one or more anti-malarial compounds or can be used to treat or prevent malaria which is resistant to one or more other anti-malarial compounds.

    Abstract translation: 本发明提供了治疗或预防受试者中的疟疾的方法。 该方法包括向受试者施用有效量的取代的四环素化合物,使得治疗或预防疟疾。 一方面,本发明涉及药物组合物,其包含有效量的用于治疗受试者的疟疾的四环素化合物和药学上可接受的载体。 本发明的取代四环素化合物可以与一种或多种抗疟疾化合物组合使用,或可用于治疗或预防对一种或多种其它抗疟疾化合物具有抗性的疟疾。

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