公开(公告)号：US20110210094A1

公开(公告)日：2011-09-01

申请号：US12962249

申请日：2010-12-07

申请人： Jeremy Gray ,  Ronald L. Cicero ,  Annette Grot ,  Natasha Popovich ,  Stephen Dudek

发明人： Jeremy Gray ,  Ronald L. Cicero ,  Annette Grot ,  Natasha Popovich ,  Stephen Dudek

IPC分类号： B05D3/10 ,  B05D5/00 ,  B05D3/00 ,  B82Y40/00

CPC分类号： G02B6/122 ,  G01N21/6428

摘要： The application relates to methods for producing islands of functionality within nanoscale apertures. Islands of functionality can be produced by growing an aperture constriction layer from the walls, functionalizing the exposed base of the aperture, then removing the aperture constriction layer. The aperture constriction layer can be produced, for example, by anodically growing an oxide layer onto a cladding through which the aperture extends. The islands of functionality can be used to bind a single molecule of interest, such as an enzyme within the nanoscale aperture.

摘要翻译： 该应用涉及在纳米尺度孔内产生功能岛的方法。 功能岛可以通过从壁上生长孔径收缩层来实现，使孔的暴露的基底功能化，然后去除孔径收缩层。 孔径收缩层可以例如通过将氧化物层阳极生长到孔径延伸穿过的包层上来产生。 功能岛可以用来结合单一的目标分子，例如在纳米尺度孔内的酶。

公开(公告)号：US20080003709A1

公开(公告)日：2008-01-03

申请号：US11476702

申请日：2006-06-29

申请人： Greta Wegner ,  Natasha Popovich

发明人： Greta Wegner ,  Natasha Popovich

IPC分类号： H01L21/00

CPC分类号： C12Q1/001 ,  G01N27/3272 ,  G03F9/00

摘要： A method for manufacturing a biosensor is provided. The method may include positioning a shadow mask containing a pattern of a plurality of feature sets over a substantially planar base layer containing a plurality of registration points. The method may also include forming at least one of the plurality of feature sets on the substantially planar base layer by selectively depositing a layer of a conductive material on the substantially planar base layer by passing the conductive material through the pattern of the shadow mask and removing the shadow mask from the substantially planar base layer. Alternatively, the method may include providing a laminate structure including a substantially planar base layer containing a plurality of registration points and a photoresist layer containing a pattern of a plurality of feature sets. The method may further include forming at least one of the plurality of feature sets on the substantially planar base layer by selectively depositing a layer of a conductive material on the substantially planar base layer by passing the conductive material through the pattern of the photoresist layer and removing the photoresist layer from the substantially planar base layer.

公开(公告)号：US08128981B2

公开(公告)日：2012-03-06

申请号：US11783568

申请日：2007-04-10

申请人： Natasha Popovich ,  Dennis Slomski ,  David Deng

发明人： Natasha Popovich ,  Dennis Slomski ,  David Deng

IPC分类号： G01N1/28

CPC分类号： G01N27/3272

摘要： A biosensor having a first conductive component is described, wherein the first conductive component includes at least one boundary formed by a first processing technique and at least one boundary formed by a second processing technique not the same as the first processing technique. The biosensor can also have a second conductive component including at least one boundary formed by the first processing technique and at least one boundary formed by a third processing technique not the same as the first processing technique. Further, the biosensor has a third conductive component including at least one boundary formed by the second processing technique and at least one boundary formed by the third processing technique not the same as the second processing technique.

摘要翻译： 描述具有第一导电部件的生物传感器，其中第一导电部件包括由第一处理技术形成的至少一个边界和由与第一处理技术不相同的第二处理技术形成的至少一个边界。 生物传感器还可以具有包括由第一处理技术形成的至少一个边界和由与第一处理技术不相同的第三处理技术形成的至少一个边界的第二导电部件。 此外，生物传感器具有包括由第二处理技术形成的至少一个边界和由与第二处理技术不相同的第三处理技术形成的至少一个边界的第三导电成分。

公开(公告)号：US20070286772A1

公开(公告)日：2007-12-13

申请号：US11783568

申请日：2007-04-10

申请人： Natasha Popovich ,  Dennis Slomski ,  David Deng

发明人： Natasha Popovich ,  Dennis Slomski ,  David Deng

IPC分类号： B01J19/00 ,  B05D5/04

CPC分类号： G01N27/3272

摘要： A biosensor having a first conductive component is described, wherein the first conductive component includes at least one boundary formed by a first processing technique and at least one boundary formed by a second processing technique not the same as the first processing technique. The biosensor can also have a second conductive component including at least one boundary formed by the first processing technique and at least one boundary formed by a third processing technique not the same as the first processing technique. Further, the biosensor has a third conductive component including at least one boundary formed by the second processing technique and at least one boundary formed by the third processing technique not the same as the second processing technique.

摘要翻译： 描述具有第一导电部件的生物传感器，其中第一导电部件包括由第一处理技术形成的至少一个边界和由与第一处理技术不相同的第二处理技术形成的至少一个边界。 生物传感器还可以具有包括由第一处理技术形成的至少一个边界和由与第一处理技术不相同的第三处理技术形成的至少一个边界的第二导电部件。 此外，生物传感器具有包括由第二处理技术形成的至少一个边界和由与第二处理技术不相同的第三处理技术形成的至少一个边界的第三导电成分。