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公开(公告)号：US20110210094A1
公开(公告)日：2011-09-01
申请号：US12962249
申请日：2010-12-07
申请人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
发明人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
CPC分类号： G02B6/122 , G01N21/6428
摘要： The application relates to methods for producing islands of functionality within nanoscale apertures. Islands of functionality can be produced by growing an aperture constriction layer from the walls, functionalizing the exposed base of the aperture, then removing the aperture constriction layer. The aperture constriction layer can be produced, for example, by anodically growing an oxide layer onto a cladding through which the aperture extends. The islands of functionality can be used to bind a single molecule of interest, such as an enzyme within the nanoscale aperture.
摘要翻译： 该应用涉及在纳米尺度孔内产生功能岛的方法。 功能岛可以通过从壁上生长孔径收缩层来实现，使孔的暴露的基底功能化，然后去除孔径收缩层。 孔径收缩层可以例如通过将氧化物层阳极生长到孔径延伸穿过的包层上来产生。 功能岛可以用来结合单一的目标分子，例如在纳米尺度孔内的酶。
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公开(公告)号：US08906670B2
公开(公告)日：2014-12-09
申请号：US12877764
申请日：2010-09-08
申请人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
发明人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
CPC分类号： G02B6/107 , C23F1/00 , C23F17/00 , C25D11/022 , C25D11/04 , G01N21/6452 , G01N21/7743 , G02B6/10 , G02B6/136
摘要： The application relates to improved optical containment structures, methods of manufacture and use, and systems for employing same. The optical containment structures generally comprise zero-mode waveguide structures having non-reflective walls. The non-reflective walls allow the preparation of optical containment regions in which the optical containment dimensions can be decoupled from the solution containment dimensions. The application also relates to methods for producing islands of functionality within nanoscale apertures.
摘要翻译： 本申请涉及改进的光学容纳结构，制造和使用方法以及使用它们的系统。 光学容纳结构通常包括具有非反射壁的零模式波导结构。 非反射壁允许制备光学容纳区域，其中光学容纳尺寸可以与溶液容纳尺寸分离。 该应用还涉及在纳米尺度孔内产生功能岛的方法。
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公开(公告)号：US08367159B2
公开(公告)日：2013-02-05
申请号：US12962249
申请日：2010-12-07
申请人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
发明人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
CPC分类号： G02B6/122 , G01N21/6428
摘要： The application relates to methods for producing islands of functionality within nanoscale apertures. Islands of functionality can be produced by growing an aperture constriction layer from the walls, functionalizing the exposed base of the aperture, then removing the aperture constriction layer. The aperture constriction layer can be produced, for example, by anodically growing an oxide layer onto a cladding through which the aperture extends. The islands of functionality can be used to bind a single molecule of interest, such as an enzyme within the nanoscale aperture.
摘要翻译： 该应用涉及在纳米尺度孔内产生功能岛的方法。 功能岛可以通过从壁上生长孔径收缩层来实现，使孔的暴露的基底功能化，然后去除孔径收缩层。 孔径收缩层可以例如通过将氧化物层阳极生长到孔径延伸穿过的包层上来产生。 功能岛可以用来结合单一的目标分子，例如在纳米尺度孔内的酶。
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公开(公告)号：US20110117637A1
公开(公告)日：2011-05-19
申请号：US12877764
申请日：2010-09-08
申请人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
发明人： Jeremy Gray , Ronald L. Cicero , Annette Grot , Natasha Popovich , Stephen Dudek
CPC分类号： G02B6/107 , C23F1/00 , C23F17/00 , C25D11/022 , C25D11/04 , G01N21/6452 , G01N21/7743 , G02B6/10 , G02B6/136
摘要： The application relates to improved optical containment structures, methods of manufacture and use, and systems for employing same. The optical containment structures generally comprise zero-mode waveguide structures having non-reflective walls. The non-reflective walls allow the preparation of optical containment regions in which the optical containment dimensions can be decoupled from the solution containment dimensions. The application also relates to methods for producing islands of functionality within nanoscale apertures.
摘要翻译： 本申请涉及改进的光学容纳结构，制造和使用方法以及使用它们的系统。 光学容纳结构通常包括具有非反射壁的零模式波导结构。 非反射壁允许制备光学容纳区域，其中光学容纳尺寸可以与溶液容纳尺寸分离。 该应用还涉及在纳米尺度孔内产生功能岛的方法。
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公开(公告)号：US07489846B2
公开(公告)日：2009-02-10
申请号：US10799020
申请日：2004-03-11
IPC分类号： G02B6/17
CPC分类号： G02B6/1225 , B82Y20/00 , G01B11/0625
摘要： Photonic crystal sensors may be created from two and three dimensional photonic crystals by introducing defects. The localization of the optical field in the defect region affords the ability to sense small volumes of analyte.
摘要翻译： 光子晶体传感器可以通过引入缺陷从二维和三维光子晶体产生。 缺陷区域中的光场的定位提供了感测小体积分析物的能力。
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公开(公告)号：US07427819B2
公开(公告)日：2008-09-23
申请号：US11073345
申请日：2005-03-04
申请人： Storrs T. Hoen , Mark A. Unkrich , William R. Trutna , John D. Larson, III , Richard C Ruby , Graham M. Flower , Annette Grot
发明人： Storrs T. Hoen , Mark A. Unkrich , William R. Trutna , John D. Larson, III , Richard C Ruby , Graham M. Flower , Annette Grot
CPC分类号： G01P15/097 , G01L1/165
摘要： An apparatus and method for measuring a target environmental variable (TEV) that employs a film-bulk acoustic resonator with motion plate. The film-bulk acoustic resonator (FBAR) includes an acoustic reflector formed in an FBAR wafer and a surface. A first electrode is formed on the surface of the acoustic reflector and has a surface. A piezoelectric layer is formed on the surface of the first electrode and has a surface. A second electrode is formed on the surface of the piezoelectric layer. A motion plate is suspended in space at a predetermined distance relative to the surface of the second electrode and is capacitively coupled to the FBAR.
摘要翻译： 一种用于测量采用具有运动板的膜 - 体声波谐振器的目标环境变量（TEV）的装置和方法。 膜 - 体声波谐振器（FBAR）包括形成在FBAR晶片和表面中的声反射器。 第一电极形成在声反射体的表面上并具有表面。 在第一电极的表面上形成压电层并具有表面。 第二电极形成在压电层的表面上。 运动板相对于第二电极的表面以预定距离悬挂在空间中，并且电容耦合到FBAR。
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公开(公告)号：US20070017276A1
公开(公告)日：2007-01-25
申请号：US11185406
申请日：2005-07-20
申请人： William Trutna , Richard Ruby , Storrs Hoen , Annette Grot , Mark Unkrich , Graham Flower , John Kofol
发明人： William Trutna , Richard Ruby , Storrs Hoen , Annette Grot , Mark Unkrich , Graham Flower , John Kofol
IPC分类号： G01N7/00
CPC分类号： G01N5/025 , G01N27/223
摘要： A humidity sensor that includes a resonant structure and a structure for altering a resonant frequency of the resonant structure in response to a change in humidity. The structures of a humidity sensor according to the present teachings may be formed in relatively small form factors and are well suited to remote applications and providing mechanisms for compensating for temperature drift.
摘要翻译： 一种湿度传感器，包括谐振结构和用于响应于湿度变化而改变谐振结构的谐振频率的结构。 根据本教导的湿度传感器的结构可以以相对小的形状因子形成，并且非常适合于远程应用并提供用于补偿温度漂移的机构。
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公开(公告)号：US20050201660A1
公开(公告)日：2005-09-15
申请号：US11078785
申请日：2005-03-11
申请人： Annette Grot , Laura Mirkarimi , Mihail Sigalas , Kai Chow
发明人： Annette Grot , Laura Mirkarimi , Mihail Sigalas , Kai Chow
CPC分类号： G02B6/1225 , B82Y20/00 , G01N21/41 , G01N21/59
摘要： A photonic crystal sensor adapted for single nanoparticle detection is disclosed. Very small single particles and single molecules may be detected. The sensors may be adapted to allow differential measurements.
摘要翻译： 公开了适用于单纳米颗粒检测的光子晶体传感器。 可以检测到非常小的单个颗粒和单个分子。 传感器可以适于允许差分测量。
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公开(公告)号：US20050200942A1
公开(公告)日：2005-09-15
申请号：US10799020
申请日：2004-03-11
申请人： Annette Grot , Kai-Cheung Chow , Laura Mirkarimi , Mihail Sigalas
发明人： Annette Grot , Kai-Cheung Chow , Laura Mirkarimi , Mihail Sigalas
CPC分类号： G02B6/1225 , B82Y20/00 , G01B11/0625
摘要： Photonic crystal sensors may be created from two and three dimensional photonic crystals by introducing defects. The localization of the optical field in the defect region affords the ability to sense small volumes of analyte.
摘要翻译： 光子晶体传感器可以通过引入缺陷从二维和三维光子晶体产生。 缺陷区域中的光场的定位提供了感测小体积分析物的能力。
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10.发明申请External-cavity laser tuned by physically-deformable distributed Bragg reflector 审中-公开通过物理可变形分布布拉格反射器调谐的外腔激光器公开(公告)号：US20050152428A1
公开(公告)日：2005-07-14
申请号：US10754780
申请日：2004-01-09
申请人： Annette Grot , Ian Hardcastle
发明人： Annette Grot , Ian Hardcastle
CPC分类号： H01S5/14 , H01S5/0617 , H01S5/141
摘要： The external cavity laser includes a resonant cavity defined at one end by a Bragg reflector and a gain medium located in the optical cavity. Coupled to the Bragg reflector is an actuator that changes the pitch of the Bragg reflector and, hence, the wavelength at which the optical cavity is resonant. The wavelength of the light generated by the external cavity laser can therefore be tuned by a single control signal applied to the actuator.
摘要翻译： 外腔激光器包括在一端由布拉格反射器和位于光腔中的增益介质限定的谐振腔。 耦合到布拉格反射器的是致动器，其改变布拉格反射器的间距，并因此改变光腔谐振的波长。 因此，可以通过施加到致动器的单个控制信号来调谐由外腔激光器产生的光的波长。
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