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公开(公告)号:US20210292759A1
公开(公告)日:2021-09-23
申请号:US16346251
申请日:2017-11-01
Inventor: Won Jong KIM , Jeong Hun KIM , Jihyun LEE , Byung Joo LEE
IPC: C12N15/115 , A61K31/713 , A61K47/61 , A61P35/00 , A61P27/02
Abstract: The present invention relates to a method for producing dextran polymer-based amplified nucleic acid aptamer nanoconstructs which efficiently and selectively capture a specific target molecule, the method comprising linking a short nucleic acid sequence or a complementary sequence for formation of nanoconstructs and a nucleic acid aptamer sequence for capture of the specific target molecule to a dextran polymer by a chemical reaction, mixing the resulting polymer/nucleic acid substances with each other to form nanostructures, subjecting the nanostructures to rolling circle amplification, thereby forming a nucleic acid aptamer having a repeated structure. The dextran polymer-based amplified nucleic acid aptamer nanoconstructs have the effect of efficiently and selectively capturing a specific target molecule.
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公开(公告)号:US20210222274A1
公开(公告)日:2021-07-22
申请号:US16310855
申请日:2017-11-07
Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION
Inventor: Hyoung Seop KIM , Jae Bok SEOL , Jae Wung BAE , Jong Chan HAN
Abstract: The present invention introduces a high entropy alloy doped with boron, comprising four or more metals selected from iron (Fe), chromium (Cr), nickel (Ni), cobalt (Co), manganese (Mn), molybdenum (Mo), aluminum (Al) and copper (Cu), and boron (B) which has single phase FCC structure.
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公开(公告)号:US20210212948A1
公开(公告)日:2021-07-15
申请号:US17212131
申请日:2021-03-25
Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION
Inventor: Yong Song GHO , Dong-Sic CHOI , Gyeongyun GO
IPC: A61K9/127 , A61K48/00 , A61K49/00 , A61K47/50 , A61K9/51 , A61K9/50 , A61K31/704 , A61K31/713 , A61K33/26 , A61K38/46
Abstract: Disclosed are cell membrane-derived nanovesicles, a method of preparing the nanovesicles, and a pharmaceutical composition and a diagnostic kit using the nanovesicles. The cell membrane-derived nanovesicles may prevent potential adverse effects because intracellular materials (e.g., genetic materials and cytosolic proteins) unnecessary for delivering therapeutic or diagnostic substances are removed from the nanovesicles. In addition, as the nanovesicles may be targeted to specific cells or tissues, therapeutic or diagnostic substances may be predominantly delivered to the targeted cells or tissues, while delivery of the substances may be inhibited. Therefore, the nanovesicles may alleviate suffering and inconvenience of patients by reducing adverse effects of therapeutic substances and by improving efficacy of the substances. In addition, the cell membrane-derived nanovesicles loaded with therapeutic or diagnostic substances and a method of preparing the nanovesicles may be used in vitro or in vivo for therapeutic or diagnostic purposes, or for experimental use.
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公开(公告)号:US11032558B2
公开(公告)日:2021-06-08
申请号:US15983608
申请日:2018-05-18
Inventor: Seho Myung , Kyung-Joong Kim , Kyeong-Cheol Yang
Abstract: A method and an apparatus for performing a Superposition Coded Modulation (SCM) scheme in a broadcasting or communication system including a controller are provided. The method includes controlling an SCM coefficient by the controller. The SCM coefficient is controlled according to a channel capacity of each layer of one or more layers in which information included in a signal is encoded.
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公开(公告)号:US20210168002A1
公开(公告)日:2021-06-03
申请号:US16636131
申请日:2018-08-03
Inventor: Yeohun YUN , Joon Ho CHO , Jubum KIM , Chanhong KIM , Jongbu LIM , Sungnam HONG
IPC: H04L27/22
Abstract: The present disclosure relates to a pre-5th-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4th-Generation (4G) communication system such as Long Term Evolution (LTE). A method of a reception device in a wireless environment according to various embodiments of the present disclosure may include receiving a signal from a transmission device, identifying that the received signal is modulated based on at least one designated modulation scheme of modulation schemes, based on identifying, generating second values by applying a first circular shift of a first direction to first values relating to first symbols of the signal, and generating third values by applying a second circular shift of a second direction which is different from the first direction, to conjugate complex values of the first values, generating second symbols of the signal based at least in part on the second values and the third values, and obtaining data about the signal based at least in part on the second symbols.
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公开(公告)号:US11005596B2
公开(公告)日:2021-05-11
申请号:US16641205
申请日:2018-08-22
Inventor: Seok-Ki Ahn , Jiwon Park , Kyeongcheol Yang , Daeyeol Yang , Sunghye Cho
Abstract: The present disclosure relates to a pre-5t-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4th-Generation (4G) communication system such as Long Term Evolution (LTE). A method for operating a transmitting stage in a wireless communication system includes generating a signal by encoding an input bit sequence according to polar code determined from a linear code, and transmitting the signal to a receiving stage. The input bit sequence includes a second frozen bit which is determined based on a first frozen bit and an information bit. The first frozen bit and the information bit precede the second frozen bit in the input bit sequence.
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公开(公告)号:US10964896B2
公开(公告)日:2021-03-30
申请号:US16398230
申请日:2019-04-29
Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION
Inventor: Tae-Woo Lee , Sanghyuk Im , Himchan Cho , Young-Hoon Kim
IPC: H01L51/00 , C09K11/06 , C01G21/16 , H01L31/00 , C09K11/02 , H01L31/032 , H01L31/0352 , C07F7/24 , C09K11/66 , H01L51/50 , B82Y20/00 , B82Y30/00 , B82Y40/00 , H01L51/42 , H01L51/44 , H01L51/52
Abstract: Provided are: a light-emitting layer for a perovskite light-emitting device; a method for manufacturing the same; and a perovskite light-emitting device using the same. The method of the present invention for manufacturing a light-emitting layer for a halide perovskite light-emitting device comprises a step of forming a first nanoparticle thin film by coating, on a member for coating a light-emitting layer, a solution comprising halide perovskite nanoparticles including a perovskite nanocrystal structure. Thereby, a nanoparticle light emitter has therein a halide perovskite having a crystal structure in which FCC and BCC are combined; and can show high color purity. In addition, it is possible to improve the luminescence efficiency and luminance of a device by making perovskite as nanoparticles and then introducing the same into a light-emitting layer.
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公开(公告)号:US20210091410A1
公开(公告)日:2021-03-25
申请号:US16954836
申请日:2019-07-24
Applicant: LG CHEM, LTD. , POSTECH ACADEMY-INDUSTRY FOUNDATION
Inventor: Daeil KIM , Moon Jeong PARK , Jonghyun CHAE , Ha Young JUNG , Suhwan KIM , Sung Chul LIM , Jihoon AHN
IPC: H01M10/0565 , H01M10/0525 , C08G65/335 , C08G65/333
Abstract: A polymer electrolyte is provided, which includes a polymer including an ethylene oxide unit; and a lithium salt, wherein the terminal of the polymer is substituted with one to four functional groups selected from the group consisting of a nitrogen compound functional group and phosphorus compound functional group, and the terminal of the polymer and the one to four functional groups are linked by one selected from the group consisting of a C2 to C20 alkylene linker, a C2 to C20 ether linker, and a C2 to C20 amine linker. A method for preparing the same is also provided.
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公开(公告)号:US10907230B2
公开(公告)日:2021-02-02
申请号:US16094323
申请日:2017-04-20
Applicant: POSCO , POSTECH ACADEMY-INDUSTRY FOUNDATION
Inventor: Joo-Hyun Ryu , Nack-Joon Kim , Sung-Hak Lee , Won-Hwi Lee , Kyoo-Young Lee , Sea-Woong Lee
IPC: C21D9/46 , C21D8/02 , C22C38/02 , C22C38/04 , C22C38/06 , C22C38/12 , C22C38/14 , C22C38/00 , C21D6/00 , C23C2/02 , C23C2/06 , C23C2/28 , C23C2/40 , C22C38/08 , C22C38/16 , C22C38/38
Abstract: Provided is an ultrahigh-strength steel sheet for a vehicle and, more specifically, to an ultrahigh-strength and high-ductility steel sheet having excellent yield ratio and a manufacturing method therefor. Provided is an ultrahigh-strength and high-ductility steel sheet for cold press forming and a manufacturing method therefor, the steel sheet ensuring ultrahigh strength and high ductility since an alloy component of steel and manufacturing conditions are controlled and, simultaneously, having excellent impact characteristics due to a high yield strength ratio (yield ratio). Provided is the steel sheet capable of satisfying formability and impact stability, which are required for a vehicle steel sheet for cold forming, and replacing a conventional steel sheet for hot press forming, thereby reducing manufacturing costs.
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公开(公告)号:US10859498B2
公开(公告)日:2020-12-08
申请号:US16289536
申请日:2019-02-28
Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION
Inventor: Seonghan Kim , Ki Hean Kim , Myoung Joon Kim , Seunghun Lee , Hoon Cheol Jang , Viet Hoan Le , Soo Hyun Park
Abstract: A method for visualization of conjunctival cells using fluoroquinolone antibiotics and a method for diagnosis of ocular lesions using the same. The method for visualization of conjunctival cells using fluoroquinolone antibiotics includes staining goblet cells of ocular conjunctiva with moxifloxacin, which is a fluoroquinolone antibiotic, and exciting the stained goblet cells with single photons in the near-UV region or in the visible region, followed by fluorescence photographing of the goblet cells, thereby enabling acquisition of morphological information on living tissue without damage to or destruction of the ocular conjunctiva. Specifically, the method for visualization of conjunctival cells includes: a conjunctiva staining step in which ocular conjunctiva is stained with a fluoroquinolone antibiotic; a light irradiation step in which the ocular conjunctiva stained with the fluoroquinolone antibiotic is irradiated with light from a light source; and a conjunctiva photographing step in which the ocular conjunctiva is photographed using an image pickup unit through the fluoroquinolone antibiotic fluorescence-excited by light in the light irradiation step, wherein, in the conjunctiva staining step, goblet cells of the ocular conjunctiva are stained with the fluoroquinolone antibiotic; in the light irradiation step, the light source emits single photons; and, in the conjunctiva photographing step, the image pickup unit photographing the ocular conjunctiva is a high-magnification fluorescence microscope or a slit lamp microscope.
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