Method for visualization of conjunctival cells using fluoroquinolone antibiotics and method for diagnosis of ocular lesions using the same

    公开(公告)号:US10859498B2

    公开(公告)日:2020-12-08

    申请号:US16289536

    申请日:2019-02-28

    Abstract: A method for visualization of conjunctival cells using fluoroquinolone antibiotics and a method for diagnosis of ocular lesions using the same. The method for visualization of conjunctival cells using fluoroquinolone antibiotics includes staining goblet cells of ocular conjunctiva with moxifloxacin, which is a fluoroquinolone antibiotic, and exciting the stained goblet cells with single photons in the near-UV region or in the visible region, followed by fluorescence photographing of the goblet cells, thereby enabling acquisition of morphological information on living tissue without damage to or destruction of the ocular conjunctiva. Specifically, the method for visualization of conjunctival cells includes: a conjunctiva staining step in which ocular conjunctiva is stained with a fluoroquinolone antibiotic; a light irradiation step in which the ocular conjunctiva stained with the fluoroquinolone antibiotic is irradiated with light from a light source; and a conjunctiva photographing step in which the ocular conjunctiva is photographed using an image pickup unit through the fluoroquinolone antibiotic fluorescence-excited by light in the light irradiation step, wherein, in the conjunctiva staining step, goblet cells of the ocular conjunctiva are stained with the fluoroquinolone antibiotic; in the light irradiation step, the light source emits single photons; and, in the conjunctiva photographing step, the image pickup unit photographing the ocular conjunctiva is a high-magnification fluorescence microscope or a slit lamp microscope.

    IMAGING METHOD USING FLUOROQUINOLONE ANTIBIOTICS AND IMAGING DEVICE FOR THE SAME

    公开(公告)号:US20190059737A1

    公开(公告)日:2019-02-28

    申请号:US15893877

    申请日:2018-02-12

    Abstract: Disclosed are an imaging method using fluoroquinolone antibiotics and an imaging device for the same, in which biological tissue is stained with Moxifloxacin as one of fluoroquinolone antibiotics, and the stained biological tissue is subjected to fluorescent image-capture through single-photon excitation with either near-ultraviolet or visible wavelength light instead of either a middle-ultraviolet light source or a femtosecond near-infrared laser device, thereby obtaining morphological information of cells in the biological tissue at a high speed without damage. To this end, an imaging method of using fluoroquinolone antibiotics includes: staining cells of the biological tissue with fluoroquinolone antibiotics; illuminating the excitation light from a light source to the biological tissue stained with the fluoroquinolone antibiotics; and capturing an image of the biological tissue through the fluoroquinolone antibiotics based fluorescence caused by the excitation light illuminated to the biological tissue, wherein the excitation light from the light source includes either near-violet or short visible wavelength light for single photon excitation of the fluoroquinolone antibiotics.

    USE OF FLUOROQUINOLONE ANTIBIOTICS
    5.
    发明申请
    USE OF FLUOROQUINOLONE ANTIBIOTICS 有权
    氟喹诺酮类抗生素的使用

    公开(公告)号:US20160341734A1

    公开(公告)日:2016-11-24

    申请号:US14943136

    申请日:2015-11-17

    Abstract: Provided are a method and an apparatus for coordinating inter-cell interference. A user equipment receives from a serving cell information on a downlink timing offset between an interfering cell and an interfered cell and a limited resource measurement, and applies the downlink timing offset to perform measurement using a radio resource indicated for the limited resource measurement, thereby allowing the user equipment to be provided services through the radio resource which substantially mitigates interference, and enhancing connectivity with a network.

    Abstract translation: 提供了用于协调小区间干扰的方法和装置。 用户设备从服务小区接收关于干扰小区和受干扰小区之间的下行链路定时偏移的信息和有限资源测量,并且使用指示用于有限资源测量的无线资源来应用下行链路定时偏移量来进行测量,从而允许 通过无线电资源提供的用户设备,其基本上减轻干扰,并增强与网络的连接性。

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