公开(公告)号：US09506894B2

公开(公告)日：2016-11-29

申请号：US13975610

申请日：2013-08-26

Applicant: Quantum Biosystems Inc.

Inventor： Tomoji Kawai ,  Soh Ryuzaki ,  Masateru Taniguchi

IPC: G01N27/447 ,  G01N33/487

CPC classification number: G01N27/44756 ,  G01N27/44752 ,  G01N33/48721

Abstract: The present invention provides a method and apparatus for controlling the moving speed of a substance, both of which can adjust the moving speed of a substance to a desired speed. The control method and control apparatus cause a substance to pass through an internal space, in which an electro-osmotic flow is generated, of a surround electrode formed so as to surround part of the moving path of the substance, whereby the control method and control apparatus change the moving speed of the substance.

Abstract translation: 本发明提供了一种用于控制物质的移动速度的方法和装置，它们都可以将物质的移动速度调节到期望的速度。 控制方法和控制装置使物质通过形成为围绕物质的移动路径的一部分而形成的环境电极的产生电渗流的内部空间，由此控制方法和控制 设备改变物质的移动速度。

公开(公告)号：US20160319342A1

公开(公告)日：2016-11-03

申请号：US15061871

申请日：2016-03-04

Applicant: Osaka University ,  Quantum Biosystems Inc.

Inventor： Tomoji Kawai ,  Masateru Taniguchi ,  Takahito Ohshiro ,  Mark Oldham ,  Eric Nordman

IPC: C12Q1/68 ,  G01N27/04 ,  G06F19/22

CPC classification number: C12Q1/6869 ,  G01N27/04 ,  G01N33/48721 ,  G06F19/22 ,  C12Q2563/116 ,  C12Q2565/631

Abstract: Devices, systems and methods for sequencing protein samples are provided. In some examples, currents generated when a monomer passes through between electrodes of a nanogap electrode pair are measured for each of several different distances, so that monomers are identified when compared to a reference physical quantity of a known monomer, which may be obtained from a current measured with a similar inter-electrode distance(s) at which each of plural kinds of monomers are identifiable and ordered with predetermined accuracy and based on a detected physical quantity obtained from a tunneling current, which may be further normalized by the use of one or more reference substances.

Abstract translation: 提供了用于测序蛋白质样品的设备，系统和方法。 在一些实例中，当在几个不同距离中的每一个测量单体通过纳米缝电极对的电极之间产生的电流，使得当与已知单体的参考物理量相比时，识别单体，其可以从 以类似的电极间距测量的电流，其中可以以预定精度识别和排序多种单体中的每一种，并且基于从隧道电流获得的检测到的物理量，其可以通过使用一个 或更多的参考物质。