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公开(公告)号：US12183521B2
公开(公告)日：2024-12-31
申请号：US18330465
申请日：2023-06-07
Inventor： Jung-Kun Lee , Gillsang Han
IPC: H01L31/0725 , H01G9/00 , H01G9/20 , H10K30/35 , H10K30/82
Abstract: Various perovskite solar cell embodiments include a flexible metal substrate (e.g., including a metal doped TiO2 layer), a perovskite layer, and a transparent electrode layer (e.g., including a dielectric/metal/dielectric structure), wherein the perovskite layer is provided between the flexible metal substrate and the transparent electrode layer. Also, various tandem solar cell embodiments including a perovskite solar cell and either a quantum dot solar cell, and organic solar cell or a thin film solar cell.
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公开(公告)号：US12180474B2
公开(公告)日：2024-12-31
申请号：US17194706
申请日：2021-03-08
Inventor： Satdarshan Monga , Kari Nejak-Bowen
IPC: C12N15/113 , A61K31/444 , A61K31/519 , A61P1/16
Abstract: A method of treating porphyria in a patient is provided comprising knocking down or reducing expression or activity of β-catenin in the patient. e.g., in the liver of a patient, to an extent effective to treat porphyria in a patient.
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公开(公告)号：US12178341B2
公开(公告)日：2024-12-31
申请号：US17357003
申请日：2021-06-24
Inventor： Alexandra Marie Delazio , David M. Brienza , Patricia Karg
Abstract: A device for use with a beverage can to secure a straw thereto includes a base configured to cooperate with an opening of the beverage can to secure the device to the beverage can and a passage formed through the base which aligns with the opening of the beverage can when the device is secured to the beverage can. The passage is configured to pass a straw therethrough.
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公开(公告)号：US20240424299A1
公开(公告)日：2024-12-26
申请号：US18700913
申请日：2022-08-11
Inventor： Changfeng Tai
Abstract: Provided herein is a method of inducing colon contractions/defecation or penile erection in a patient, including stimulating one or more sacral roots of the patient's spinal cord with a plurality of electrical pulses, wherein the electrical pulses are delivered at a frequency of from about 3 Hz to about 10 Hz or from about 10 Hz to about 80 Hz.
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25.发明申请公开(公告)号：US20240418712A1
公开(公告)日：2024-12-19
申请号：US18818711
申请日：2024-08-29
Inventor： Prashant Kumta , Mitali Patil , David Okonkwo , Robert Kormos
Abstract: The invention relates to ex-situ biosensors that impedimetrically detect one or more target biomarkers of interest in a bodily fluid sample derived from a patient. The biosensors include a multi-array of conducting material, such as platinum wires, having immobilized thereon antibody and/or aptamer that is selected to specifically and selectively bind to the one or more target biomarkers of interest. The biosensors are contacted with a portion of the bodily fluid sample, and the antibody and/or aptamer binds to the target biomarker(s) of interest in the bodily fluid sample. As a result, an electrochemical impedance signal is generated and therefore, a change in the electrochemical impedance is indicative of the presence of the target biomarker(s) of interest in the bodily fluid sample. The biosensors are point-of-care, on-demand devices that can be used in a medical environment, as well as in domestic and health emergency settings.
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Patent Agency Ranking
26.发明授权公开(公告)号：US12169934B2
公开(公告)日：2024-12-17
申请号：US17805126
申请日：2022-06-02
Inventor： Nghi Nguyen , Shandong Wu
Abstract: A system, device and method of imaging using a real-time, AI-enabled analysis device coupled to an imaging device during an image scan of a subject includes: receiving data corresponding to a plurality of image frames from the imaging device and user input identifying a region of interest (ROI) in a first image frame; providing data corresponding to the first image frame, including the identified ROI and data corresponding to the remaining image frames to the AI-enabled data processing system; accepting a plurality of valid image frames from the plurality of image frames based on a predefined set of computer vision rules and a minimum accepted frame threshold; calculating, frame by frame, an ROI function value of the plurality of valid image frames; determining whether a predetermined ROI function value has been reached; and alerting an operator of the imaging device that the predetermined ROI function value has been reached.
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公开(公告)号：US12161778B2
公开(公告)日：2024-12-10
申请号：US17072651
申请日：2020-10-16
IPC: A61L27/36 , A61K31/7088 , A61K31/7105 , A61K35/22 , A61K35/36 , A61K35/38 , A61L27/38 , A61L27/54 , A61P35/00 , C12N15/115
Abstract: A composition is disclosed herein that includes isolated ECM-derived nanovesicles and a pharmaceutically acceptable carrier. Methods are producing the ECM-derived nanovesicles are also disclosed. These ECM-derived nanovesicles can be included in pharmaceutical compositions, bioscaffolds, and devices. Methods for using these ECM-derived nanovesicles are provided.
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公开(公告)号：US20240404707A1
公开(公告)日：2024-12-05
申请号：US18688105
申请日：2022-09-02
Inventor： Jianhua LUO , Aatur Dilip SINGHI , Baoguo REN , Chien-Cheng TSENG , George MICHALOPOULOS , Michael A. NALESNIK , Michelle A. WOOD-TRAGESER , Shuchang LIU , Yanping YU
Abstract: Described herein are prediction models based on the transcriptomic, exomic, and/or radiological analyses on tissue samples to predict the likelihood of the original cancer (such as Hepatocellular carcinoma (HCC)) recurrence into the liver transplant. An example computer implemented method for predicting the likelihood of liver cancer recurrence 5 into a liver transplant includes receiving gene expression data related to a liver tissue sample for a subject having a liver cancer, inputting the gene expression data into a trained machine learning model, and predicting, using the trained machine learning model, a risk of recurrence of the liver cancer in the subject after liver transplantation.
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29.发明申请公开(公告)号：US20240399152A1
公开(公告)日：2024-12-05
申请号：US18690998
申请日：2022-09-09
Inventor： Marc Philip Powell , Marco Capogrosso , Douglas J. Weber , Nikhil Verma , Peter C. Gerszten , Elvira Pirondini , Erynn Sorensen , Erick Fabrizio Carranza Urquizo , Lee Fisher
Abstract: Disclosed herein are methods for treating impairment of a limb in a subject. Particular methods comprise applying a therapeutically effective amount of an electrical stimulus to dorsal roots, dorsal rootlets, or dorsal root ganglia, of sensory neurons innervating the limb of the subject, wherein the impairment is a motor impairment and/or a proprioception impairment due to neurological disorder or injury, the electrical stimulus is applied with one or more electrodes controlled by a neurostimulator, and the one or more electrodes are implanted in the epidural space at the dorsolateral aspect of the spinal cord and proximate to the dorsal roots or dorsal rootlets of the sensory neurons innervating the limb of the subject, or the one or more electrodes are implanted proximate to dorsal root ganglia of sensory neurons innervating the limb of the subject.
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公开(公告)号：US20240392563A1
公开(公告)日：2024-11-28
申请号：US18693092
申请日：2022-09-19
Inventor： Amir Alavi , Kaveh Barri , Lev Khazanovich , Jake Kline , Qianyun Zhang
Abstract: A metamaterial, comprising: an auxetic lattice structure with snap-through buckling behavior comprising a plurality of rows; wherein the lattice defines a holey arrangement array; and cement, concrete or any other brittle materials disposed in the auxetic lattice structure.
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