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公开(公告)号：US20220257112A1
公开(公告)日：2022-08-18
申请号：US17662582
申请日：2022-05-09
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Stephan WYDER , Philip M. BUSCEMI , Matthias PFISTER , Alexander HOLZER
IPC: A61B3/10 , G01B9/02004 , G01B9/02091 , A61B3/12
Abstract: An OCT system for measuring a retina as part of an eye health monitoring and diagnosis system. The OCT system includes an OCT interferometer, where the interferometer comprises a light source or measurement beam and a scanner for moving the beam on the retina of a patient's eye, and a processor configured to execute instructions to cause the scanner to move the measurement beam on the retina in a scan pattern. The scan pattern is a continuous pattern that includes a plurality of lobes. The measurement beam may be caused to move on the retina by the motion of a mirror that intercepts and redirects the measurement beam. The mirror position may be altered by the application of a drive signal to one or more actuators that respond to the drive signal by rotating the mirror about an axis or axes.
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公开(公告)号：US20220084197A1
公开(公告)日：2022-03-17
申请号：US17444806
申请日：2021-08-10
Applicant: ACUCELA INC.
Inventor： Stephan WYDER , Matthias PFISTER , Cyril STOLLER , Philip M. BUSCEMI
Abstract: A neural network is trained to segment interferogram images. A first plurality of interferograms are obtained, where each interferograms corresponds to data acquired by an OCT system using a first scan pattern, annotating each of the plurality of interferograms to indicate a tissue structure of a retina, training a neural network using the plurality of interferograms and the annotations, inputting a second plurality of interferograms corresponding to data acquired by an OCT system using a second scan pattern and obtaining an output of the trained neural network indicating the tissue structure of the retina that was scanned using the second scan pattern. The system and methods may instead receive a plurality of A-scans and output a segmented image corresponding to a plurality of locations along an OCT scan pattern.
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公开(公告)号：US20240411155A1
公开(公告)日：2024-12-12
申请号：US18812767
申请日：2024-08-22
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Philip M. BUSCEMI , Amitava GUPTA , Stefan BAUER , Benjamin CROOK , Julien SAUVET
Abstract: An apparatus to treat refractive error of an eye comprises an optic comprising an optical zone and a peripheral defocus optical structure to form images of a plurality of stimuli anterior or posterior to a peripheral portion of a retina of the eye. In some embodiments, the peripheral defocus optical structure located outside the optical zone. In some embodiments, the peripheral defocus optical structure comprises optical power to focus light to a different depth of the eye than the optical zone. In some embodiments, the optic comprises one or more of a lens, an optically transparent substrate, a beam splitter, a prism, or an optically transmissive support.
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公开(公告)号：US20240103300A1
公开(公告)日：2024-03-28
申请号：US18508894
申请日：2023-11-14
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Philip M. BUSCEMI , Pascal LOSER , Ben CROOK , Massimo PINAZZA , Jim NIEBANCK , James PHILLIPS , Stefan BAUER
CPC classification number: G02C7/083 , G02C5/146 , G02C11/10 , G02C2200/08
Abstract: An electronic case for electronic spectacles may include a base comprising a cavity formed therein. A first spectacle retention device may be located within the cavity. The first spectacle retention device may be configured to retain spectacles. An electrical control system may be included. An electrical connector may be configured to couple the electrical control system in electronic communication with the spectacles.
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公开(公告)号：US20230241410A1
公开(公告)日：2023-08-03
申请号：US18163376
申请日：2023-02-02
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Benjamin CROOK , Stefan BAUER , Philip M. BUSCEMI , Amitava GUPTA , Jonas GERMANN
IPC: A61N5/06
CPC classification number: A61N5/0622 , A61N2005/0648 , A61N2005/0651
Abstract: A wearer adjustable apparatus is configured for a wearer to view an object and adjust stimuli projected into the eye by adjusting the location of the projection optics, for example with movement of the projection optics relative to one or more components of a support such as an eyeglass frame. In some embodiments, the projection system comprises an adjustable retainer for the wearer to adjust first active projection elements coupled to a first support in front of a first eye in relation to second projection optics coupled to a second support in front of a second eye of the wearer. In some embodiments, the apparatus comprises oculars comprising the projection optics and corrective lenses configured for the wearer to adjust positions of the lenses and projection optics in front of the wearer's eyes in order to project therapeutic spots onto a desired location relative to the wearer's retinas.
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Patent Agency Ranking
公开(公告)号：US20230026753A1
公开(公告)日：2023-01-26
申请号：US17936263
申请日：2022-09-28
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Philip M. BUSCEMI , Matthias PFISTER , Stephan WYDER , Amitava GUPTA
IPC: A61B3/10 , G01B9/02091
Abstract: An OCT axial length measurement device is configured to measure an area of the retina within a range from about 0.05 mm to about 2.0 mm. The area can be measured with a scanned measurement beam or plurality of substantially fixed measurement beams. The OCT measurement device may comprise a plurality of reference optical path lengths, in which a first optical path length corresponds to a first position of a cornea, and a second optical path length corresponds to a second position of the retina, in which the axial length is determined based on a difference between the first position and the second position. An axial length map can be generated to determine alignment of the eye with the measurement device and improve accuracy and repeatability of the measurements. In some embodiments, the OCT measurement device comprises a swept source vertical cavity surface emitting laser (“VCSEL”).
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27.发明申请公开(公告)号：US20230020468A1
公开(公告)日：2023-01-19
申请号：US17757748
申请日：2020-09-02
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Philip M. BUSCEMI
Abstract: Improved optical coherence tomography systems and methods to measure retinal data are presented. The systems may be compact, provide in-home monitoring, and have automation to allow the patient to measure himself or herself.
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公开(公告)号：US20220404638A1
公开(公告)日：2022-12-22
申请号：US17820738
申请日：2022-08-18
Applicant: ACUCELA INC.
Inventor： Philip M. BUSCEMI , Ryo KUBOTA
Abstract: Systems, devices, apparatuses and methods for an active projection system that may be incorporated into spectacles, contact lenses or provided as an add-on layer to existing spectacles or lenses. The active projection system operates to generate a stimulus or stimuli for viewing by a person's eye. The stimulus or stimuli creates an image that is defocused in front of the person's retina and can assist in slowing or stopping the progression of myopia or other refractive errors in the person.
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公开(公告)号：US20220304573A1
公开(公告)日：2022-09-29
申请号：US17647585
申请日：2022-01-10
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Philip M. BUSCEMI , Matthias PFISTER , Stephan WYDER , Amitava GUPTA
IPC: A61B3/10 , G01B9/02091
Abstract: An OCT axial length measurement device is configured to measure an area of the retina within a range from about 0.05 mm to about 2.0 mm. The area can be measured with a scanned measurement beam or plurality of substantially fixed measurement beams. The OCT measurement device may comprise a plurality of reference optical path lengths, in which a first optical path length corresponds to a first position of a cornea, and a second optical path length corresponds to a second position of the retina, in which the axial length is determined based on a difference between the first position and the second position. An axial length map can be generated to determine alignment of the eye with the measurement device and improve accuracy and repeatability of the measurements. In some embodiments, the OCT measurement device comprises a swept source vertical cavity surface emitting laser (“VCSEL”).
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公开(公告)号：US20220214564A1
公开(公告)日：2022-07-07
申请号：US17655496
申请日：2022-03-18
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Philip M. BUSCEMI , Amitava GUPTA , Stefan BAUER , Benjamin CROOK , Julien SAUVET
Abstract: An apparatus to treat refractive error of an eye comprises an optic comprising an optical zone and a peripheral defocus optical structure to form images of a plurality of stimuli anterior or posterior to a peripheral portion of a retina of the eye. In some embodiments, the peripheral defocus optical structure located outside the optical zone. In some embodiments, the peripheral defocus optical structure comprises optical power to focus light to a different depth of the eye than the optical zone. In some embodiments, the optic comprises one or more of a lens, an optically transparent substrate, a beam splitter, a prism, or an optically transmissive support.
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