公开(公告)号：US20190135949A1

公开(公告)日：2019-05-09

申请号：US16247708

申请日：2019-01-15

Applicant: Agency for Science, Technology and Research

Inventor： Simon Cool ,  Victor Nurcombe

IPC: C08B37/00 ,  A61K38/39 ,  A61L27/20 ,  A61L27/54 ,  A61K31/727 ,  A61L27/56 ,  A61L27/50

Abstract: A heparan sulphate that binds vitronectin is disclosed.

公开(公告)号：US10245281B2

公开(公告)日：2019-04-02

申请号：US14814680

申请日：2015-07-31

Applicant: Agency for Science, Technology and Research

Inventor： Simon Cool ,  Victor Nurcombe

IPC: A61P9/10 ,  A61K31/727 ,  C08B37/00 ,  A61K31/737 ,  A61L27/34 ,  A61L27/54 ,  A61K38/18

Abstract: Heparan sulphate HS7 is disclosed, together with the use of HS7 in the growth and/or development and/or regeneration of tissue.

公开(公告)号：US20170326059A1

公开(公告)日：2017-11-16

申请号：US15527995

申请日：2015-11-19

Applicant: Agency for Science, Technology and Research ,  L'Oreal

Inventor： Simon Cool ,  Victor Nurcombe ,  Charbel Bouez ,  Diah Saraswati Bramono

IPC: A61K8/73 ,  A61Q19/08 ,  A61Q19/00 ,  C08B37/00

CPC classification number: A61K8/73 ,  A61K2800/10 ,  A61Q19/007 ,  A61Q19/08 ,  C08B37/0075

Abstract: Affinity purification of fibroblast growth factor 2-binding heparan sulphate from porcine mucosa (HS8) is disclosed. Also disclosed is a process for the care of keratinous material(s), comprising the application or administration of HS8, or a composition comprising thereof, to keratinous material(s). The composition may be used to improve the condition of skin, such as smoothing the skin, restoring skin elasticity and firmness, or decreasing or preventing wrinkles, and may be formulated for topical or transdermal administration.

公开(公告)号：US20170319615A1

公开(公告)日：2017-11-09

申请号：US15527972

申请日：2015-11-19

Applicant: Agency for Science, Technology and Research

Inventor： Simon Cool ,  Victor Nurcombe

IPC: A61K31/727 ,  C08B37/00

CPC classification number: A61K31/727 ,  A61K9/0014 ,  A61K35/28 ,  A61K38/1825 ,  A61L15/28 ,  A61L26/0023 ,  A61P17/02 ,  C08B37/0075 ,  A61K2300/00 ,  C08L5/10

Abstract: Affinity purification of fibroblast growth factor 2-binding heparan sulphate from porcine mucosa (HS8) is disclosed. Also disclosed is the use of HS8 in repair and regeneration of the skin for treating wounds, burns, ulcers and other skin injuries.

公开(公告)号：US20160215072A1

公开(公告)日：2016-07-28

申请号：US14893979

申请日：2014-05-27

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Simon Cool ,  Victor Nurcombe

IPC: C08B37/00 ,  A61K31/727 ,  A61L27/50 ,  A61L27/20 ,  A61L27/54

CPC classification number: C08B37/0075 ,  A61K31/727 ,  A61K38/39 ,  A61L27/20 ,  A61L27/50 ,  A61L27/54 ,  A61L27/56 ,  A61L2300/236 ,  A61K2300/00

Abstract: A heparan sulphate that binds vitronectin is disclosed.

Abstract translation: 公开了结合玻连蛋白的硫酸乙酰肝素。