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公开(公告)号：US20200345782A1
公开(公告)日：2020-11-05
申请号：US16875486
申请日：2020-05-15
Applicant: Agency for Science, Technology and Research
Inventor： Lawrence Stanton , Padmapriya Sathiyanathan , Simon Cool , Victor Nurcombe , Rebekah M. Samsonraj
IPC: A61K35/28 , C12Q1/6881 , A61K35/545 , C12N5/0775
Abstract: A method for providing a sub-population of stem cell or plurality of stem cells by determining or modulating GSTT1 expression level or genotype is disclosed together with uses of the stem cells.
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公开(公告)号：US20170143766A1
公开(公告)日：2017-05-25
申请号：US15318909
申请日：2015-06-26
Applicant: Agency for Science, Technology and Research
Inventor： Lawrence Stanton , Padmapriya Sathiyanathan , Simon Cool , Victor Nurcombe , Rebekah M. Samsonraj
IPC: A61K35/28 , C12N5/0775 , C12Q1/68
CPC classification number: A61K35/28 , A61K35/545 , C12N5/0662 , C12N5/0663 , C12Q1/6881 , C12Q2600/158 , C12Y205/01018
Abstract: A method for providing a sub-population of stem cell or plurality of stem cells by determining or modulating GSTT1 expression level or genotype is disclosed together with uses of the stem cells.
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公开(公告)号：US20160115251A1
公开(公告)日：2016-04-28
申请号：US14891564
申请日：2013-05-16
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Victor Nurcombe , Simon Cool
IPC: C08B37/00 , A61K38/18 , C12N5/0775 , A61K9/00 , A61L27/20 , A61K31/737 , A61K35/28
CPC classification number: C08B37/0075 , A61K9/0019 , A61K31/737 , A61K35/28 , A61K38/1825 , A61L27/20 , A61L2430/02 , C08B37/0078 , C12N5/0662 , C12N5/0663 , C12N2501/115 , C12N2501/91
Abstract: A novel class of structurally and functionally related isolated Heparan sulphate is disclosed. The novel class of Heparan sulphates has been found to bind FGF2 and enhance the proliferation of stem cells whilst maintaining their pluripotency/multipotency.
Abstract translation: 公开了一类新型的结构和功能相关的分离的硫酸肝素。 已经发现新型的硫酸乙酰肝素结合FGF2并增强干细胞的增殖，同时保持它们的多能性/多能性。
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公开(公告)号：US10596296B2
公开(公告)日：2020-03-24
申请号：US15307407
申请日：2015-04-30
Applicant: Agency for Science, Technology and Research
Inventor： Simon Cool , Victor Nurcombe , Jonathan Lee
IPC: A61L27/20 , A61L27/38 , A61L27/52 , A61L27/54 , A61K31/727 , C08B37/00 , C07K14/495 , A61L15/44 , A61L15/60 , A01N1/02 , A61K8/73 , A61L27/34 , C12N5/0775
Abstract: A heparan sulphate that binds TGPβ1 is disclosed.
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公开(公告)号：US10266612B2
公开(公告)日：2019-04-23
申请号：US14891564
申请日：2013-05-16
Applicant: Agency for Science, Technology and Research
Inventor： Victor Nurcombe , Simon Cool
IPC: C08B37/10 , C08B37/00 , C12N5/0775 , A61K9/00 , A61K31/737 , A61K35/28 , A61K38/18 , A61L27/20
Abstract: A novel class of structurally and functionally related isolated Heparan sulphate is disclosed. The novel class of Heparan sulphates has been found to bind FGF2 and enhance the proliferation of stem cells while maintaining their pluripotency/multipotency.
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Patent Agency Ranking
公开(公告)号：US20180258193A1
公开(公告)日：2018-09-13
申请号：US15542123
申请日：2016-01-08
Applicant: Agency for Science, Technology and Research
Inventor： Simon Cool , Victor Nurcombe
IPC: C08B37/00 , A61K31/727 , A61K38/18 , A61L33/00
CPC classification number: C08B37/0075 , A61K31/727 , A61K38/1858 , A61K45/06 , A61L33/0011 , A61L2300/42 , A61L2400/18 , A61P17/02 , C08B37/0078 , C08B37/0081 , A61K2300/00
Abstract: Affinity purification of platelet-derived growth factor-binding heparan sulphate from porcine mucosa (HS6) is disclosed. Also disclosed is the use of HS6 in repair and regeneration of the skin for treating wounds, burns, ulcers and other skin injuries.
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公开(公告)号：US20150328251A1
公开(公告)日：2015-11-19
申请号：US14814680
申请日：2015-07-31
Applicant: Agency for Science, Technology and Research
Inventor： Simon Cool , Victor Nurcombe
IPC: A61K31/727 , A61K38/18
CPC classification number: A61K31/727 , A61K31/737 , A61K38/1866 , A61L27/34 , A61L27/54 , A61L2300/412 , A61P9/10 , C08B37/0078 , C08L5/00
Abstract: Heparan sulphate HS7 is disclosed, together with the use of HS7 in the growth and/or development and/or regeneration of tissue.
Abstract translation: 公开了硫酸肝素HS7以及在组织的生长和/或发育和/或再生中使用HS7。
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公开(公告)号：US10723813B2
公开(公告)日：2020-07-28
申请号：US15542123
申请日：2016-01-08
Applicant: Agency for Science, Technology and Research
Inventor： Simon Cool , Victor Nurcombe
Abstract: Affinity purification of platelet-derived growth factor-binding heparan sulphate from porcine mucosa (HS6) is disclosed. Also disclosed is the use of HS6 in repair and regeneration of the skin for treating wounds, burns, ulcers and other skin injuries.
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公开(公告)号：US20170043053A1
公开(公告)日：2017-02-16
申请号：US15307407
申请日：2015-04-30
Applicant: Agency for Science, Technology and Research
Inventor： Simon Cool , Victor Nurcombe , Jonathan Lee
IPC: A61L27/20 , A61L27/38 , A61L27/52 , A01N1/02 , C07K14/495 , A61K8/73 , A61L27/34 , C12N5/0775 , C08B37/00 , A61L27/54
Abstract: A heparan sulphate that binds TGPβ1 is disclosed.
Abstract translation: 公开了结合TGPβ1的硫酸乙酰肝素。
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公开(公告)号：US11806368B2
公开(公告)日：2023-11-07
申请号：US16875486
申请日：2020-05-15
Applicant: Agency for Science, Technology and Research
Inventor： Lawrence Stanton , Padmapriya Sathiyanathan , Simon Cool , Victor Nurcombe , Rebekah M. Samsonraj
IPC: A61K35/28 , C12Q1/6881 , A61K35/545 , C12N5/0775
CPC classification number: A61K35/28 , A61K35/545 , C12N5/0662 , C12N5/0663 , C12Q1/6881 , C12Y205/01018 , C12Q2600/158
Abstract: A method for providing a sub-population of stem cell or plurality of stem cells by determining or modulating GSTT1 expression level or genotype is disclosed together with uses of the stem cells.
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