公开(公告)号：US20200368453A1

公开(公告)日：2020-11-26

申请号：US16842468

申请日：2020-04-07

Applicant: AMGEN INC.

Inventor： Mark Ka Lai Lee ,  Stephanie Toy ,  Valerie M. Fenster

IPC: A61M5/32 ,  A61M5/19 ,  A61M5/42 ,  A61M5/20 ,  A61M5/315 ,  A61M5/44

Abstract: An injector for delivering a therapeutic product may include a base having a flexible surface that conforms to various body contours of a patient and defines one or more an injection chambers. The injector may have a height that is substantially less than its width, thereby defining a low profile, which provides a larger more stable base that can pinch or stretch the skin in a controlled manner. The larger base can also accommodate larger volumes via multiple injection chambers and/or large combined primary containers.

公开(公告)号：US20200215273A1

公开(公告)日：2020-07-09

申请号：US16589037

申请日：2019-09-30

Applicant: AMGEN INC.

Inventor： Scott R. Gibson ,  Mark Ka Lai Lee ,  Donald Busby ,  Stephanie Toy ,  Suhas Krishna ,  Francisca Tan-Malecki ,  Ferry Tamtoro

IPC: A61M5/44 ,  A61M5/315 ,  A61M5/20 ,  A61M5/142 ,  A61M5/162 ,  A61M5/172 ,  A61M5/31

Abstract: A drug delivery system includes a reservoir and a drug delivery device coupled to the reservoir. The drug delivery device also may include at least one temperature-sensitive component and a lock having locked and unlocked states. The system further includes an output device, and a controller coupled to the lock and the output device. The controller may also include a temperature sensor, or may be coupled to the temperature sensor. The controller is programmed or configured to determine if the temperature of a drug in the reservoir or of the temperature-sensitive component exceeds an upper limit or is below a lower limit, and to activate the lock in either event. The controller is also programmed or configured to determine, directly or indirectly, if the temperature subsequently is between the upper and lower limits, and to unlock lock as a consequence.

公开(公告)号：US10682474B2

公开(公告)日：2020-06-16

申请号：US15040372

申请日：2016-02-10

Applicant: AMGEN INC.

Inventor： Lawrence Ring ,  Dhairya Mehta ,  Stephanie Toy ,  Ferry Tamtoro ,  Alexander Stuart Cairns ,  Scott R. Gibson

IPC: A61M5/32 ,  A61M5/142 ,  A61M5/42 ,  A61M25/02 ,  A61M5/20 ,  A61M25/00 ,  C12N9/64 ,  C07K14/535 ,  A61K38/19 ,  A61K38/28 ,  A61K38/26 ,  A61M5/158 ,  A61M5/14 ,  A61M5/31 ,  A61K9/00 ,  A61M5/30

Abstract: A drug delivery device includes a blunt cannula and a reservoir. The blunt cannula has a cylindrical wall that defines an axial passage between a first end and a second end of the blunt cannula. The wall has at least a first tapered region at the first end to define an opening in fluid communication with the axial passage and adapted at the first end to resist interruption of fluid flow through the axial passage and out of the first end of the blunt cannula. The reservoir is connected to the second end of the blunt cannula.

公开(公告)号：US10646664B2

公开(公告)日：2020-05-12

申请号：US14776693

申请日：2014-03-14

Applicant: Amgen Inc.

Inventor： Mark Ka Lai Lee ,  Stephanie Toy ,  Valerie M. Fenster

IPC: A61M5/32 ,  A61M5/20 ,  A61M5/19 ,  A61M5/42 ,  A61M5/315 ,  A61M5/44 ,  A61M5/30 ,  A61M5/34

Abstract: An injector for delivering a therapeutic product may include a base having a flexible surface that conforms to various body contours of a patient and defines one or more an injection chambers. The injector may have a height that is substantially less than its width, thereby defining a low profile, which provides a larger more stable base that can pinch or stretch the skin in a controlled manner. The larger base can also accommodate larger volumes via multiple injection chambers and/or large combined primary containers.

公开(公告)号：US20190351152A1

公开(公告)日：2019-11-21

申请号：US16531654

申请日：2019-08-05

Applicant: AMGEN INC

Inventor： Valerie M. Fenster ,  Stephanie Toy ,  Mark Ka Lai Lee ,  Denise Meyer

IPC: A61M5/42 ,  A61M5/50 ,  A61M5/20 ,  A61M5/32

Abstract: An injector such as a needle-type autoinjector having a flexible flange disposed at an injection end of the injector for stretching or pinching the skin of the injection site. The flexible flange may be removably attached to the injector or integrated into the injector during manufacturing. Further, an injector having a palm button disposed at an activation end of the injector for activating an injection cycle of the injector. The palm button may be removably attached to the injector or integrated into the injector during manufacturing. Still further, a holding device for one-handed operation of an injector, the holding device having a sleeve and at least one hand rest coupled to the sleeve, the sleeve and hand rest providing ergonomic holding and operation of the injector. Still further, autoinjector needle shield having an enlarged, rounded lip for contacting the skin at the injection site.

公开(公告)号：USD864378S1

公开(公告)日：2019-10-22

申请号：US29611595

申请日：2017-07-24

Applicant: AMGEN INC.

Designer： Sahba Tafazoli ,  Emily Card Razaqi ,  Valerie M. Fenster ,  Stephanie Toy ,  Scott R. Gibson ,  Denise Meyer ,  Erik Timpers ,  Catherine Arboleda Tamura ,  Peter T. So ,  Ravi Sawhney ,  Lance Hussey ,  Harnish Jani ,  Kurt Botsai ,  Young Bang ,  Gregory VanderPol ,  Shushuo Wu ,  Cathy Tran ,  Noureddine Malaeb