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公开(公告)号：US11540946B2
公开(公告)日：2023-01-03
申请号：US17057689
申请日：2020-04-07
Applicant: AMO Development, LLC
Inventor： Richard Hofer , Alexander Vankov , Jenny Wang , David A. Dewey , Phillip Gooding , Georg Schuele
Abstract: Methods and related apparatus for real-time process monitoring during laser-based refractive index modification of an intraocular lens. During in situ laser treatment of the IOL to modify the refractive index of the IOL material, a signal from the IOL is measured to determine the processing effect of the refractive index modification, and based on the determination, to adjust the laser system parameters to achieve intended processing result. The signal measured from the IOL may be a fluorescent signal induced by the treatment laser, a fluorescent signal induced by an external illumination source, a temporary photodarkening effect, a color change, or a refractive index change directly measured by phase stabilized OCT.
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公开(公告)号：US20220269829A1
公开(公告)日：2022-08-25
申请号：US17662829
申请日：2022-05-10
Applicant: AMO Development, LLC
Inventor： Javier G. Gonzalez , David A. Dewey , Noah Bareket , Michael A. Campos , Yu-tai Ray Chen , David D. Scott
Abstract: A laser eye surgery system produces a treatment beam that includes a plurality of laser pulses. An optical coherence tomography (OCT) subsystem produces a source beam used to locate one or more structures of an eye. The OCT subsystem is used to sense the distance between a camera objective on the underside of the laser eye surgery system and the patient's eye. Control electronics compare the sensed distance with a pre-determined target distance, and reposition a movable patient support toward or away the camera objective until the sensed distance is at the pre-determined target distance. A subsequent measurement dependent upon the spacing between the camera objective and the patient's eye is performed, such as determining the astigmatic axis by observing the reflection of a plurality of point source LEDs arranged in concentric rings off the eye.
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23.发明申请公开(公告)号：US20220015949A1
公开(公告)日：2022-01-20
申请号：US17057691
申请日：2020-04-08
Applicant: AMO Development, LLC
Inventor： Alexander Vankov , Jenny Wang , David A. Dewey , Phillip Gooding , Richard Hofer , Georg Schuele
Abstract: The XYZ beam position of an ophthalmic laser system is calibrated by measuring a fluorescent signal induced by the focused laser beam in a thin glass coverslip via multiphoton absorption. A video camera measures the XY position and intensity of the fluorescent signal as the focused laser beam strikes the coverslip. The Z position of the focus is determined by scanning the targeted z position and identifying the Z scanner position of peak fluorescence. An OCT system measures the real space Z location of the coverslip, which is correlated with the Z scanner position. Other laser system parameters are assessed by repeatedly scanning a lower energy laser beam in a piece of IOL material, and observing damage (scattering voids) formation in the IOL material. Based on the rate of damage formation, laser system parameters such as beam quality, numerical aperture, pulse energy, and pulse duration, etc. can be assessed.
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24.发明授权公开(公告)号：US11154424B2
公开(公告)日：2021-10-26
申请号：US16375784
申请日：2019-04-04
Applicant: AMO Development, LLC
Inventor： Georg Schuele , Alexander Vankov , Jenny Wang , David A. Dewey , Tianheng Wang , Michael Wiltberger , Mihai State , Phillip Gooding
Abstract: A method of altering a refractive property of a crosslinked acrylic polymer material by irradiating the material with a high energy pulsed laser beam to change its refractive index. The method is used to alter the refractive property, and hence the optical power, of an implantable intraocular lens after implantation in the patient's eye. In some examples, the wavelength of the laser beam is in the far red and near IR range and the light is absorbed by the crosslinked acrylic polymer via two-photon absorption at high laser pulse energy. The method also includes designing laser beam scan patterns that compensate for effects of multiphone absorption such as a shift in the depth of the laser pulse absorption location, and compensate for effects caused by high laser pulse energy such as thermal lensing. The method can be used to form a Fresnel lens in the optical zone.
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公开(公告)号：US20210077300A1
公开(公告)日：2021-03-18
申请号：US17103907
申请日：2020-11-24
Applicant: AMO Development, LLC
Inventor： David A. Dewey , Javier G. Gonzalez , Georg Schuele , David D. Scott
Abstract: An ophthalmic measurement and laser surgery system includes: a laser source; a corneal topography subsystem; an axis determining subsystem; a ranging subsystem comprising an Optical Coherence Tomographer (OCT); and a refractive index determining subsystem. All of the subsystems are under the operative control of a controller. The controller is configure to: operate the corneal topography subsystem to obtain corneal surface information; operate the axis determining subsystem to identify one or more ophthalmic axes of the eye; operate the OCT to sequentially scan the eye in a plurality of OCT scan patterns, the plurality of scan patterns configured to determine an axial length of the eye; operate the refractive index determining subsystem so to determine an index of refraction of one or more ophthalmic tissues, wherein at least one of the corneal surface information, ophthalmic axis information, and axial length is modified based on the determined index of refraction.
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Patent Agency Ranking
公开(公告)号：US10849789B2
公开(公告)日：2020-12-01
申请号：US15269781
申请日：2016-09-19
Applicant: AMO Development, LLC
Inventor： David A. Dewey , Javier G. Gonzalez , Georg Schuele , David D. Scott
Abstract: An ophthalmic measurement and laser surgery system includes: a laser source; a corneal topography subsystem; an axis determining subsystem; a ranging subsystem comprising an Optical Coherence Tomographer (OCT); and a refractive index determining subsystem. All of the subsystems are under the operative control of a controller. The controller is configure to: operate the corneal topography subsystem to obtain corneal surface information; operate the axis determining subsystem to identify one or more ophthalmic axes of the eye; operate the OCT to sequentially scan the eye in a plurality of OCT scan patterns, the plurality of scan patterns configured to determine an axial length of the eye; operate the refractive index determining subsystem so to determine an index of refraction of one or more ophthalmic tissues, wherein at least one of the corneal surface information, ophthalmic axis information, and axial length is modified based on the determined index of refraction.
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公开(公告)号：US20250025344A1
公开(公告)日：2025-01-23
申请号：US18907307
申请日：2024-10-04
Applicant: AMO Development, LLC
Inventor： Richard Hofer , Alexander Vankov , Jenny Wang , David A. Dewey , Phillip Gooding , Georg Schuele
Abstract: Methods and related apparatus for real-time process monitoring during laser-based refractive index modification of an intraocular lens. During in situ laser treatment of the IOL to modify the refractive index of the IOL material, a signal from the IOL is measured to determine the processing effect of the refractive index modification, and based on the determination, to adjust the laser system parameters to achieve intended processing result. The signal measured from the IOL may be a fluorescent signal induced by the treatment laser, a fluorescent signal induced by an external illumination source, a temporary photodarkening effect, a color change, or a refractive index change directly measured by phase stabilized OCT.
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公开(公告)号：US20230130142A1
公开(公告)日：2023-04-27
申请号：US18145020
申请日：2022-12-22
Applicant: AMO Development, LLC
Inventor： Richard Hofer , Alexander Vankov , Jenny Wang , David A. Dewey , Phillip Gooding , Georg Schuele
Abstract: Methods and related apparatus for real-time process monitoring during laser-based refractive index modification of an intraocular lens. During in situ laser treatment of the IOL to modify the refractive index of the IOL material, a signal from the IOL is measured to determine the processing effect of the refractive index modification, and based on the determination, to adjust the laser system parameters to achieve intended processing result. The signal measured from the IOL may be a fluorescent signal induced by the treatment laser, a fluorescent signal induced by an external illumination source, a temporary photodarkening effect, a color change, or a refractive index change directly measured by phase stabilized OCT.
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公开(公告)号：US20230111508A1
公开(公告)日：2023-04-13
申请号：US18064848
申请日：2022-12-12
Applicant: AMO Development, LLC
Inventor： David A. Dewey , Michael Wiltberger , Phillip Gooding , Georg Schuele
Abstract: During a process of refractive index modification of an intraocular lens (IOL) using an ophthalmic laser system, optical position monitoring of the IOL is performed by a video camera system viewing the top surface of the IOL. Fiducials are incorporated into the IOL at manufacture, or created in-vivo with laser. The monitoring method employs a defined area of interest (AOI) to limit the number of pixels to be analyzed, to achieve adequately high acquisition speed. In one example, the AOI contains 5 camera scan line segments, each line segment having sufficient pixels to create a stable amplitude signature. Successive frames of the AOI are analyzed to detect movement of the fiducial and/or to determine whether the fiducial has been lost.
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30.发明申请公开(公告)号：US20220273493A1
公开(公告)日：2022-09-01
申请号：US17664216
申请日：2022-05-19
Applicant: AMO DEVELOPMENT, LLC
Inventor： Rajeshwari Srinivasan , Jeffrey A. Golda , Javier G. Gonzalez , David D. Scott , David A. Dewey , Noah Bareket , Georg Schuele
Abstract: A method of cataract surgery in an eye of a patient includes identifying a feature selected from the group consisting of an axis, a meridian, and a structure of an eye by corneal topography and forming fiducial mark incisions with a laser beam along the axis, meridian or structure in the cornea outside the optical zone of the eye. A laser cataract surgery system a laser source, a topography measurement system, an integrated optical subsystem, and a processor in operable communication with the laser source, corneal topography subsystem and the integrated optical system. The processor includes a tangible non-volatile computer readable medium comprising instructions to determine one of an axis, meridian and structure of an eye of the patient based on the measurements received from topography measurement system, and direct the treatment beam so as to incise radial fiducial mark incisions.
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