公开(公告)号：US5762281A

公开(公告)日：1998-06-09

申请号：US801971

申请日：1997-02-18

申请人： Michael Foley

发明人： Michael Foley

IPC分类号： B65H75/28 ,  B65H75/44 ,  B65H75/48

CPC分类号： B65H75/44 ,  B65H75/28

摘要： An automatically loading cord reel device which includes a cord reel housing, a rotatably contained spool with indexing slots, and a coiled spring which is coupled to said spool. A spring loaded indexing lever interacts with the indexing slots on the spool. The spool is pre-wound a fixed number of turns and the pre-wound device includes an exposed portion of a cord attachment device which is attached to the spool and extends out from a cord reeling aperture in the reel housing. The embodied cord attachment device includes a tongue-shaped strip of flexible material with an circular aperture and connected distally extending slot formed therethrough the exposed end portion of the tongue. A locking pin aperture also extends through the exposed portion of the tongue for receiving a locking pin. The pre-wound spool is thereby held in place by the locking pin to prevent unwinding. To use the device, knotted cords are placed through the readily accessible exposed cord attachment aperture and distally slid into the slot. Upon removal of the locking pin, the cords are automatically reeled inside the device to a pre-determined and/or indexably controlled length.

摘要翻译： 一种自动加载的卷线盘装置，包括一个线卷轴壳体，一个带有分度槽的可旋转地容纳的卷轴，以及一个联接到所述卷轴上的螺旋弹簧。 弹簧加载的分度杆与卷轴上的分度槽相互作用。 卷轴预缠绕固定数量的匝，并且预缠绕装置包括附接到卷轴并从卷轴壳体中的绳索卷绕孔延伸出的帘线附接装置的暴露部分。 具体的绳索附接装置包括具有圆形孔的柔性材料的舌状条带和通过其暴露的舌部的端部形成的远端延伸槽。 锁定销孔也延伸穿过舌头的暴露部分以接收锁定销。 预缠绕的卷轴因此通过锁定销保持在适当位置以防止展开。 为了使用该装置，打结的绳索通过易于接近的暴露的绳索附着孔放置并远离地滑入槽中。 在移除锁定销时，帘线被自动地卷绕在装置内以预定的和/或可变形的受控长度。

公开(公告)号：US20110180468A1

公开(公告)日：2011-07-28

申请号：US12692100

申请日：2010-01-22

申请人： Michael Foley ,  Sylvain Champoux ,  Steve Leduc ,  Jonathan George ,  Ilko Paunov

发明人： Michael Foley ,  Sylvain Champoux ,  Steve Leduc ,  Jonathan George ,  Ilko Paunov

IPC分类号： F01M11/03 ,  B08B7/00

CPC分类号： B01D29/52 ,  B01D29/114 ,  B01D29/92 ,  Y10T137/0402

摘要： A filter housing providing improved cleanliness is provided. In one embodiment, the filter housing includes a body, a cover plate and a clean fluid manifold assembly. The body has a first plenum defined therein which is configured to accommodate multiple filter elements. The clean fluid manifold having a recess and plurality of index tubes. The recess bounds a second plenum, wherein surfaces of the recess have been machined, or otherwise have had surface material removed to provide a smooth, clean and contamination free surface. The plurality of index tubes have a first end coupled to the clean fluid manifold and a second end extending into the first plenum, the second end of the index tube configured to engage with a filter element.

摘要翻译： 提供了提供改进的清洁度的过滤器壳体。 在一个实施例中，过滤器壳体包括主体，盖板和清洁流体歧管组件。 主体具有限定在其中的第一增压室，其构造成容纳多个过滤元件。 清洁流体歧管具有凹陷和多个折射管。 凹部限定了第二增压室，其中凹部的表面已被加工，或者已经除去了表面材料以提供光滑，清洁和无污染的表面。 多个分度管具有联接到清洁流体歧管的第一端和延伸进入第一增压室的第二端，引导管的第二端构造成与过滤元件接合。

公开(公告)号：US20100081713A1

公开(公告)日：2010-04-01

申请号：US12406716

申请日：2009-03-18

申请人： Geeta Sharma ,  Ralf Altmeyer ,  Vishal Pendharker ,  Yu Chen ,  Michael Foley

发明人： Geeta Sharma ,  Ralf Altmeyer ,  Vishal Pendharker ,  Yu Chen ,  Michael Foley

IPC分类号： A61K31/351 ,  A61K31/215 ,  A61K31/135 ,  A61K31/13 ,  A61P31/12

CPC分类号： A61K45/06 ,  A61K31/13 ,  A61K31/135 ,  A61K31/215 ,  A61K31/351 ,  A61K2300/00

摘要： The present invention provides compositions, methods, and kits for treating or preventing a viral infection (e.g., an infection caused by an influenza virus).

摘要翻译： 本发明提供用于治疗或预防病毒感染（例如由流感病毒引起的感染）的组合物，方法和试剂盒。

公开(公告)号：USD603841S1

公开(公告)日：2009-11-10

申请号：US29242920

申请日：2005-11-16

申请人： Michael Foley

设计人： Michael Foley

公开(公告)号：US20070101323A1

公开(公告)日：2007-05-03

申请号：US11261317

申请日：2005-10-28

申请人： Michael Foley ,  Stephen Friesen ,  James Hoelter

发明人： Michael Foley ,  Stephen Friesen ,  James Hoelter

IPC分类号： G06F9/455

CPC分类号： G06F9/45537 ,  H04L29/12311 ,  H04L29/12396 ,  H04L61/2084 ,  H04L61/2525

摘要： Network configuration settings for an virtual guest environment are adjusted in response to detecting a change in a networking environment. The changes in the networking environment may be detected through updated host operating system settings or other means. After detecting a change, virtual machine software may initiate reconfiguration of virtual machine network configuration settings, guest operating system network configuration settings, or both. The reconfiguration allows network connectivity for the guest operating system to be restored without user interaction. The updated network configuration settings may be retrieved from a host operating system, the network, local memory or some other source. Network settings for a new network may be saved in memory and recalled when the host machine attempts to connect to the network in the future.

摘要翻译： 响应于检测到网络环境中的变化，调整虚拟客户机环境的网络配置设置。 可以通过更新的主机操作系统设置或其他方式来检测网络环境中的变化。 检测到更改后，虚拟机软件可能会启动虚拟机网络配置设置，客户机操作系统网络配置设置或两者的重新配置。 重新配置允许客户机操作系统的网络连接在没有用户交互的情况下恢复。 可以从主机操作系统，网络，本地存储器或一些其他源检索更新的网络配置设置。 新网络的网络设置可能会保存在内存中，并在主机将来尝试连接到网络时进行调用。

公开(公告)号：US20060074030A1

公开(公告)日：2006-04-06

申请号：US11213534

申请日：2005-08-26

申请人： Julian Adams ,  Alfredo Castro ,  Michael Foley ,  Somarajan Janardanan Nair ,  Marta Nevalainen ,  James Porter ,  Martin Tremblay

发明人： Julian Adams ,  Alfredo Castro ,  Michael Foley ,  Somarajan Janardanan Nair ,  Marta Nevalainen ,  James Porter ,  Martin Tremblay

IPC分类号： A61K31/7052 ,  A61K31/4747 ,  C07D491/10

CPC分类号： C07D491/04

摘要： The present invention provides compositions and methods for modulating smoothened-dependent pathway activation. The present invention provides analogs of cyclopamine that can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, Ptc loss-of-function or smoothened gain-of-function mutations. The compounds of the present invention are particularly useful in treating cancers.

摘要翻译： 本发明提供用于调节平滑依赖性途径激活的组合物和方法。 本发明提供环巴胺的类似物，其可用于抵消刺猬蛋白途径的不期望的活化的表型效应，例如由刺猬蛋白获得功能，Ptc功能丧失或平滑获得功能突变引起的表型效应。 本发明的化合物特别可用于治疗癌症。

公开(公告)号：US5249120A

公开(公告)日：1993-09-28

申请号：US641161

申请日：1991-01-14

申请人： Michael Foley

发明人： Michael Foley

IPC分类号： G06Q10/06 ,  G06Q10/08 ,  G06Q30/02

CPC分类号： G06Q10/06 ,  G06Q10/0631 ,  G06Q10/087 ,  G06Q30/0283

摘要： An automated manufacturing cost estimating method and system with indirect cost allocation which identifies a material in an initial state for manufacturing a product in a final state; defines an operation for converting the material from its initial state into the final state of the product; calculates the direct labor cost for each operation based on direct labor hours and calculates the indirect cost specifically allocated for each operation based on consumption of overhead cost elements by the operation; and sums the cost calculated for each operation to determine the total cost of manufacture of a part. Also disclosed is a cost analyzing method and system which utilizes the cost estimating method and system by identifying a plurality of different materials in an initial state for manufacturing a product in a final state and defining a number of manufacturing operations for converting each of the different materials from its initial state into the final state of the product; generating a plurality of paths through the interconnected operations between the different materials in the initial state and the product in the final state; determining a predetermined cost parameter associated with each operation; and accumulating the determined cost parameters along each path.

摘要翻译： 一种具有间接成本分配的自动化制造成本估算方法和系统，其识别在最终状态下制造产品的初始状态的材料; 定义了将材料从初始状态转换为产品的最终状态的操作; 计算基于直接劳动时间的每个操作的直接人工成本，并根据操作计算基于间接成本要素消耗的每个操作专门分配的间接成本; 并计算每个操作的成本，以确定零件的制造总成本。 还公开了一种成本分析方法和系统，其利用成本估算方法和系统，通过在最初状态下识别用于制造产品的初始状态的多种不同材料并且定义用于转换每种不同材料的制造操作的数量 从初始状态到产品的最终状态; 通过处于初始状态的不同材料和最终状态下的产品之间的互连操作产生多条路径; 确定与每个操作相关联的预定成本参数; 并且沿着每个路径累积确定的成本参数。