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公开(公告)号：US4677075A
公开(公告)日：1987-06-30
申请号：US859339
申请日：1986-05-05
CPC分类号： G01N33/72 , Y10T436/10 , Y10T436/103332 , Y10T436/108331
摘要： A stable control solution is provided for the determination of urobilinogen. The control solution comprises an aqueous solution of about 3-12% ethylene glycol, about 0.1% protein and preferably about 40-400 mg/dl urobilinogen, said composition buffered to pH about 8.0-9.0 and retained in a hermetically sealed container under a blanket of inert gas.
摘要翻译： 提供稳定的对照溶液用于尿胆素原的测定。 对照溶液包含约3-12％乙二醇，约0.1％蛋白质，优选约40-400mg / dl尿胆素原的水溶液，所述组合物缓冲至pH约8.0-9.0，并保持在气密密封的容器中， 的惰性气体。
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公开(公告)号：US4579824A
公开(公告)日：1986-04-01
申请号：US495629
申请日：1983-05-18
CPC分类号： G01N33/96 , G01N2496/05 , Y10T436/10 , Y10T436/101666 , Y10T436/107497
摘要： A hematology control is disclosed which is useful for clinical hematology procedures and, in particular, mean corpuscular volume (MCV) determinations. The hematology control comprises an aqueous suspension of red blood cells in which varying levels of MCV are provided by applying to the red cell component, after light treatment with aldehyde, an osmotic pressure that is directly proportional to the desired red blood cell size.
摘要翻译： 公开了用于临床血液学程序，特别是平均红细胞容积（MCV）测定的血液学控制。 血液学控制包括红细胞的水性悬浮液，其中通过施用红细胞成分，在用醛光处理后，与所需红细胞大小成正比的渗透压，提供不同程度的MCV。
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23.发明授权Method for increasing shelf-life of a serum conjugated bilirubin reference composition and composition produced thereby 失效提高血清结合胆红素参考组合物的保存期限的方法及由此制备的组合物
公开(公告)号：US4344864A
公开(公告)日：1982-08-17
申请号：US202269
申请日：1980-10-30
CPC分类号： G01N33/728 , G01N33/96 , Y10T436/103332
摘要： A stable blood serum conjugated bilirubin reference composition characterized in that the composition possess a pH of from about 8.2 to bout 9.2 and comprises (a) a sulfhydryl compound in an amount sufficient to enhance the stability of the conjugated bilirubin and (b) a chelating agent in an amount sufficient to bind all the metals present in the blood serum moiety of the composition. This blood serum conjugated bilirubin composition when stored in a gas impervious vial under an inert atmosphere has an excellent shelf life.
摘要翻译： 一种稳定的血清结合胆红素参照组合物，其特征在于所述组合物具有约8.2至约9.2的pH，并且包含（a）足以提高共轭胆红素稳定性的量的巯基化合物和（b）螯合剂 其量足以结合存在于组合物的血清部分中的所有金属。 当在惰性气氛下储存在不透气小瓶中时，该血清共轭胆红素组合物具有优良的保质期。
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公开(公告)号：US4199471A
公开(公告)日：1980-04-22
申请号：US961184
申请日：1978-11-16
IPC分类号： G01N33/96
CPC分类号： G01N33/96 , G01N2496/05 , G01N2496/70 , Y10T436/101666 , Y10T436/102499 , Y10T436/107497 , Y10T436/108331
摘要： A freeze-stable liquid blood control standard and method is provided for the quality control of the measurement of blood pH and gases in the clinical laboratory. The blood control standard comprises a sealed receptacle containing specially treated red cells and a gaseous head space at least equal to about the volume of the red cells. The special treatment comprises thorough washing and separating the red cells from the plasma components and mild treatment with aldehyde, slow admixture with lower aliphatic diol or triol, and retention in a buffered solution. The special treatment optionally includes treating at least a portion of the red cells with carbon monoxide. The head space comprises from 0-15% CO.sub.2, 0-25% O.sub.2 and the balance N.sub.2 and/or inert gas.
摘要翻译： 提供了一种冷冻稳定的液体血液控制标准和方法，用于临床实验室血液pH和气体测量的质量控制。 血液控制标准包括密封容器，其容纳特别处理的红细胞和至少等于红细胞体积的气体头部空间。 特殊处理包括彻底清洗和分离红细胞与血浆成分，用醛轻度处理，与低级脂肪族二醇或三醇缓慢混合，并保留在缓冲溶液中。 特殊处理任选包括用一氧化碳处理至少一部分红细胞。 顶部空间包含0-15％的二氧化碳，0-25％的O 2和余量为N 2和/或惰性气体。
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25.发明授权Method of storing a biological reference control standard and biological reference control standard obtained thereby 失效存储由此获得的生物参考对照标准品和生物参考对照标准品的方法
公开(公告)号：US4189401A
公开(公告)日：1980-02-19
申请号：US925482
申请日：1978-07-17
申请人： Allan L. Louderback
发明人： Allan L. Louderback
CPC分类号： A01N1/0221 , A01N1/02 , G01N33/96 , G01N2496/05 , Y10T436/10 , Y10T436/102499 , Y10T436/104165 , Y10T436/104998 , Y10T436/105831 , Y10T436/106664 , Y10T436/108331 , Y10T436/109163
摘要： An improved method of storing and shipping a blood serum reference composition comprising in its non-biological component from about 40 to about 85 weight percent water, from about 15 to about 60 weight percent of at least one alkylene polyol having from 2-5 carbon atoms, the remainder being chiefly at least one natural biological material selected from a group consisting of blood serum, enzyme, metabolites, electrolytes, and hormones. The improvement comprises storing and/or shipping the composition at a temperature below the freezing point thereof.
摘要翻译： 一种改进的存储和运送血清参考组合物的方法，其包含其非生物组分中约40至约85重量％的水，约15至约60重量％的至少一种具有2-5个碳原子的亚烷基多元醇 其余主要是选自血清，酶，代谢物，电解质和激素中的至少一种天然生物材料。 该改进包括在低于其凝固点的温度下储存和/或运输该组合物。
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公开(公告)号：US3973913A
公开(公告)日：1976-08-10
申请号：US653346
申请日：1976-01-29
申请人： Allan L. Louderback
发明人： Allan L. Louderback
CPC分类号： G01N33/96 , G01N2496/05 , G01N2496/70 , Y10T436/101666 , Y10T436/102499 , Y10T436/107497 , Y10T436/108331
摘要： A stable blood control standard and method is provided for the quality control of the measurement of blood pH and gases in the clinical laboratory. The blood control standard comprises a sealed receptacle containing specially treated red cells and a gaseous head space at least equal to about the volume of the red cells. The special treatment comprises thorough washing and separating the red cells from the plasma components and mild treatment with aldehyde and retention in a buffered solution. The head space comprises from 0-15% CO.sub.2, 0-25% O.sub.2 and the balance N.sub.2 and/or inert gas.
摘要翻译： 提供了稳定的血液控制标准和方法，用于临床实验室血液pH和气体测量的质量控制。 血液控制标准包括密封容器，其容纳特别处理的红细胞和至少等于红细胞体积的气体头部空间。 特殊处理包括彻底清洗和分离红细胞与血浆成分，并用醛轻度处理并保留在缓冲溶液中。 顶部空间包含0-15％的二氧化碳，0-25％的O 2和余量为N 2和/或惰性气体。
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