公开(公告)号：US07970790B2

公开(公告)日：2011-06-28

申请号：US12120228

申请日：2008-05-13

申请人： Mark Yang ,  Anton Amirov ,  Jonathan Tang

发明人： Mark Yang ,  Anton Amirov ,  Jonathan Tang

IPC分类号： G06F7/00 ,  G06F17/30

CPC分类号： G06F21/6227 ,  G06F21/305 ,  G06F21/6218 ,  G06F2221/2141

摘要： Architecture for cell-based security on a per-user basis. A security model for this capability includes not only dimension level tables, but is extended to include cell level tables. The security model can include existing dimension tables, plus cell security tables that include a cell permissions table, a cell qualifiers table and a table that includes both the cell permissions table, a cell qualifiers. Metadata associated with the security applied to the cells for a given user can be stored locally in a local metadata store for retrieval and application against a data cube that an authenticated and authorized user is querying. In a specific implementation, the cell level security is employed in a performance management server application, where authentication is performed remotely by an authentication service, but the authorization function is performed local to the performance management server application.

摘要翻译： 基于每个用户的基于单元的安全性的架构。 此功能的安全模型不仅包括维度级别表，而且还包括单元级别表。 安全模型可以包括现有维度表，以及单元格安全表，其中包括单元权限表，单元限定符表和包含单元格许可表，单元限定符的表。 与应用于给定用户的单元的安全性相关联的元数据可以本地存储在本地元数据存储中，用于针对被认证和授权的用户正在查询的数据多维数据集进行检索和应用。 在具体实现中，在性能管理服务器应用中使用小区级安全性，其中认证由认证服务远程执行，但是授权功能在性能管理服务器应用的本地执行。

公开(公告)号：US20090287704A1

公开(公告)日：2009-11-19

申请号：US12120228

申请日：2008-05-13

申请人： Mark Yang ,  Anton Amirov ,  Jonathan Tang

发明人： Mark Yang ,  Anton Amirov ,  Jonathan Tang

IPC分类号： G06F17/30

CPC分类号： G06F21/6227 ,  G06F21/305 ,  G06F21/6218 ,  G06F2221/2141

摘要： Architecture for cell-based security on a per-user basis. A security model for this capability includes not only dimension level tables, but is extended to include cell level tables. The security model can include existing dimension tables, plus cell security tables that include a cell permissions table, a cell qualifiers table and a table that includes both the cell permissions table, a cell qualifiers. Metadata associated with the security applied to the cells for a given user can be stored locally in a local metadata store for retrieval and application against a data cube that an authenticated and authorized user is querying. In a specific implementation, the cell level security is employed in a performance management server application, where authentication is performed remotely by an authentication service, but the authorization function is performed local to the performance management server application.

摘要翻译： 基于每个用户的基于单元的安全性的架构。 此功能的安全模型不仅包括维度级别表，而且还包括单元级别表。 安全模型可以包括现有维度表，以及单元格安全表，其中包括单元权限表，单元限定符表和包含单元格许可表，单元限定符的表。 与应用于给定用户的单元的安全性相关联的元数据可以本地存储在本地元数据存储中，用于针对被认证和授权的用户正在查询的数据多维数据集进行检索和应用。 在具体实现中，在性能管理服务器应用中使用小区级安全性，其中认证由认证服务远程执行，但是授权功能在性能管理服务器应用的本地执行。

公开(公告)号：US20090048552A1

公开(公告)日：2009-02-19

申请号：US12138291

申请日：2008-06-12

申请人： ALI HASSAN ,  Lester John Lloyd ,  Michael Orth ,  Mark Yang ,  Binh Luong ,  Brian K. Courtney ,  Peter J. Fitzgerald

发明人： ALI HASSAN ,  Lester John Lloyd ,  Michael Orth ,  Mark Yang ,  Binh Luong ,  Brian K. Courtney ,  Peter J. Fitzgerald

IPC分类号： A61M1/36

CPC分类号： A61M1/008

摘要： Methods and devices for selectively removing an agent from a physiological site, e.g., a physiological efferent fluid collection site, are provided. Aspects of the invention include fluid removal (e.g., aspiration) devices having a fluid removal element and a flow modulator positioned at a distal end of the fluid removal element. The flow modulator is configured to converge intersecting fluid flow paths into the fluid removal element. Also provided are systems and kits for performing the subject methods. The subject invention finds use in a variety of different applications, including the selective removal of both therapeutic and diagnostic agents from a variety of different physiological sites.

摘要翻译： 提供了用于从生理部位例如生理传出液收集部位选择性除去药剂的方法和装置。 本发明的方面包括具有流体去除元件的流体去除（例如，抽吸）装置和位于流体移除元件的远端处的流量调节器。 流量调节器被配置为将交叉的流体流动路径会聚到流体去除元件中。 还提供了用于执行主题方法的系统和套件。 本发明可用于各种不同的应用，包括从各种不同的生理部位选择性地除去治疗剂和诊断剂。

公开(公告)号：US20070207210A1

公开(公告)日：2007-09-06

申请号：US11557486

申请日：2006-11-07

申请人： Larry Brown ,  Mark Yang ,  Ed O'Connell

发明人： Larry Brown ,  Mark Yang ,  Ed O'Connell

IPC分类号： A61K39/395 ,  A61K38/28 ,  A61K9/14

CPC分类号： A61K9/0019 ,  A61K9/10 ,  A61K9/1688 ,  A61K38/28 ,  C07K16/2866 ,  C07K16/2896 ,  C07K16/36 ,  C07K2317/24

摘要： The present disclosure relates to compositions of methods of making and compositions small compositions of particles of an active agent. In accordance with the method of production, the active agent is dissolved in an aqueous or aqueous-miscible solvent containing a dissolved phase-separation enhancing agent (PSEA) to form a solution in a single liquid phase. The solution is subjected to a liquid-solid phase separation to cause the active agent to form small spherical particles that are substantially amorphous or non-crystalline and are injectable through fine bore needles at high concentrations. The particles exhibit the pharmacokinetic and pharmacodynamnic properties of the active agent. The disclosure has special application for higher molecular weight proteins such as antibodies.

摘要翻译： 本公开涉及制备方法的组合物和组合物活性剂颗粒的小组合物。 根据生产方法，将活性剂溶解在含有溶解的相分离增强剂（PSEA）的水溶性或水溶性溶剂中以形成单一液相中的溶液。 使溶液进行液 - 固相分离，使活性剂形成基本上无定形或非结晶的小球形颗粒，并且可以通过高浓度的细孔针进行注射。 颗粒表现出活性剂的药代动力学和药效学性质。 本公开内容对于分子量较高的蛋白质如抗体具有特殊应用。

公开(公告)号：US20070060888A1

公开(公告)日：2007-03-15

申请号：US11220874

申请日：2005-09-06

申请人： Thomas Goff ,  Michael Orth ,  Mark Yang ,  Hung Ha

发明人： Thomas Goff ,  Michael Orth ,  Mark Yang ,  Hung Ha

IPC分类号： A61M1/00

CPC分类号： A61M1/008 ,  A61M25/003 ,  A61M25/0068 ,  A61M25/007 ,  A61M25/0082

摘要： An aspiration catheter comprises a catheter body having an aspiration lumen therethrough. The distal opening of the aspiration lumen can be modified in various ways or can have the addition of structure in order to disrupt sealing between the port and material being aspirated. Examples of modifications include slots, castellations, zig-zag features, and other geometries which resist sealing of aspirated material. Blades, rollers, vibrating elements, and other structures may be provided within or around the distal end of the aspiration lumen in order to dislodge and disrupt aspirated material which can seal against the opening.

摘要翻译： 抽吸导管包括具有穿过其中的抽吸腔的导管体。 可以以各种方式修改吸入腔的远端开口，或者可以增加结构以便破坏端口和被抽吸的材料之间的密封。 修改的实例包括槽，槽，Z字形特征以及其它抵抗吸气材料密封的几何形状。 叶片，辊，振动元件和其他结构可以设置在吸入腔的远端内部或周围，以便移除和干扰可以密封开口的吸入材料。