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    SENSOR-ASSISTED CATHETER-BASED PROCEDURES
    1.
    发明申请
    SENSOR-ASSISTED CATHETER-BASED PROCEDURES 有权
    传感器辅助导管器程序

    公开(公告)号：US20090299445A1

    公开(公告)日：2009-12-03

    申请号：US11720012

    申请日：2005-11-22

    申请人： Peter J. Fitzgerald ,  Ali Hassan ,  Brian K. Courtney

    发明人： Peter J. Fitzgerald ,  Ali Hassan ,  Brian K. Courtney

    IPC分类号： A61N1/05 ,  A61B5/02

    CPC分类号： A61N1/056

    摘要： Methods, systems and devices for effectively and safely accessing and verifying a target site within a vessel or body cavity undergoing a catheter-based procedure or treatment. The present invention further includes the accurate delivery an instrument, an implantable device and/or materials to the target site. The present invention is particularly useful for transvenously assessing the suitability of a target site within the coronary vasculature for placement of a pacing electrode and transvenously placing the pacing electrode at the target site.

    摘要翻译： 用于有效和安全地进入和验证经历基于导管的程序或治疗的血管或体腔内的靶位点的方法，系统和装置。 本发明还包括将仪器，可植入装置和/或材料准确地输送到目标部位。 本发明特别适用于经静脉评估冠状动脉血管内的靶位置适用于放置起搏电极并将起搏电极经常放置在靶位点。

    Sensor-assisted catheter-based procedures
    4.
    发明授权
    Sensor-assisted catheter-based procedures 有权
    传感器辅助导管手术

    公开(公告)号：US09463313B2

    公开(公告)日：2016-10-11

    申请号：US11720012

    申请日：2005-11-22

    申请人： Peter J. Fitzgerald ,  Ali Hassan ,  Brian K. Courtney

    发明人： Peter J. Fitzgerald ,  Ali Hassan ,  Brian K. Courtney

    IPC分类号： A61B5/04 ,  A61N1/05

    CPC分类号： A61N1/056

    摘要： Methods, systems and devices for effectively and safely accessing and verifying a target site within a vessel or body cavity undergoing a catheter-based procedure or treatment. The present invention further includes the accurate delivery an instrument, an implantable device and/or materials to the target site. The present invention is particularly useful for transvenously assessing the suitability of a target site within the coronary vasculature for placement of a pacing electrode and transvenously placing the pacing electrode at the target site.

    摘要翻译： 用于有效和安全地进入和验证经历基于导管的程序或治疗的血管或体腔内的靶位点的方法，系统和装置。 本发明还包括将仪器，可植入装置和/或材料准确地输送到目标部位。 本发明特别适用于经静脉评估冠状动脉血管内的靶位置适用于放置起搏电极并将起搏电极经常放置在靶位点。

    METHODS AND DEVICES FOR REMOVAL OF A MEDICAL AGENT FROM A PHYSIOLOGICAL EFFERENT FLUID COLLECTION SITE
    5.
    发明申请
    METHODS AND DEVICES FOR REMOVAL OF A MEDICAL AGENT FROM A PHYSIOLOGICAL EFFERENT FLUID COLLECTION SITE 有权
    从生理效能流体采集站点移除医疗药剂的方法和装置

    公开(公告)号：US20090048552A1

    公开(公告)日：2009-02-19

    申请号：US12138291

    申请日：2008-06-12

    申请人： ALI HASSAN ,  Lester John Lloyd ,  Michael Orth ,  Mark Yang ,  Binh Luong ,  Brian K. Courtney ,  Peter J. Fitzgerald

    发明人： ALI HASSAN ,  Lester John Lloyd ,  Michael Orth ,  Mark Yang ,  Binh Luong ,  Brian K. Courtney ,  Peter J. Fitzgerald

    IPC分类号： A61M1/36

    CPC分类号： A61M1/008

    摘要： Methods and devices for selectively removing an agent from a physiological site, e.g., a physiological efferent fluid collection site, are provided. Aspects of the invention include fluid removal (e.g., aspiration) devices having a fluid removal element and a flow modulator positioned at a distal end of the fluid removal element. The flow modulator is configured to converge intersecting fluid flow paths into the fluid removal element. Also provided are systems and kits for performing the subject methods. The subject invention finds use in a variety of different applications, including the selective removal of both therapeutic and diagnostic agents from a variety of different physiological sites.

    摘要翻译： 提供了用于从生理部位例如生理传出液收集部位选择性除去药剂的方法和装置。 本发明的方面包括具有流体去除元件的流体去除（例如，抽吸）装置和位于流体移除元件的远端处的流量调节器。 流量调节器被配置为将交叉的流体流动路径会聚到流体去除元件中。 还提供了用于执行主题方法的系统和套件。 本发明可用于各种不同的应用，包括从各种不同的生理部位选择性地除去治疗剂和诊断剂。

    Methods and devices for removal of a medical agent from a physiological efferent fluid collection site
    6.
    发明授权
    Methods and devices for removal of a medical agent from a physiological efferent fluid collection site 有权
    用于从生理传出液收集部位移除药剂的方法和装置

    公开(公告)号：US08308673B2

    公开(公告)日：2012-11-13

    申请号：US12138291

    申请日：2008-06-12

    申请人： Ali Hassan ,  Lester John Lloyd ,  Michael Orth ,  Mark Yang ,  Binh Luong ,  Brian K. Courtney ,  Peter J. Fitzgerald

    发明人： Ali Hassan ,  Lester John Lloyd ,  Michael Orth ,  Mark Yang ,  Binh Luong ,  Brian K. Courtney ,  Peter J. Fitzgerald

    IPC分类号： A61M37/00 ,  A61M1/00 ,  A61M31/00

    CPC分类号： A61M1/008

    摘要： Methods and devices for selectively removing an agent from a physiological site, e.g., a physiological efferent fluid collection site, are provided. Aspects of the invention include fluid removal (e.g., aspiration) devices having a fluid removal element and a flow modulator positioned at a distal end of the fluid removal element. The flow modulator is configured to converge intersecting fluid flow paths into the fluid removal element. Also provided are systems and kits for performing the subject methods. The subject invention finds use in a variety of different applications, including the selective removal of both therapeutic and diagnostic agents from a variety of different physiological sites.

    摘要翻译： 提供了用于从生理部位例如生理传出液收集部位选择性除去药剂的方法和装置。 本发明的方面包括具有流体去除元件的流体去除（例如，抽吸）装置和位于流体移除元件的远端处的流量调节器。 流量调节器被配置为将交叉的流体流动路径会聚到流体去除元件中。 还提供了用于执行主题方法的系统和套件。 本发明可用于各种不同的应用，包括从各种不同的生理部位选择性地除去治疗剂和诊断剂。

    Methods, systems and devices for establising communication between hollow organs and tissue lumens
    8.
    发明授权
    Methods, systems and devices for establising communication between hollow organs and tissue lumens 有权
    用于建立中空器官和组织腔之间的通信的方法，系统和装置

    公开(公告)号：US07967808B2

    公开(公告)日：2011-06-28

    申请号：US11664480

    申请日：2005-10-06

    申请人： Peter J. Fitzgerald ,  Brian K. Courtney ,  Ali Hassan

    发明人： Peter J. Fitzgerald ,  Brian K. Courtney ,  Ali Hassan

    IPC分类号： A61M25/16

    CPC分类号： A61M25/0082 ,  A61M25/0068 ,  A61M25/0127

    摘要： Methods, systems and devices for establishing communication between organs and/or tissue lumens. The devices include catheters having magnetized distal ends which are configured to magnetically couple to each other such that a coaxial alignment is established between two or more catheters. The systems include two or more the subject catheters. The methods include use of the catheters and magnetically coupling them to establish a continuous passageway between them.

    摘要翻译： 用于建立器官和/或组织腔之间的通信的方法，系统和装置。 这些装置包括具有磁化远端的导管，其构造成彼此磁耦合，使得在两个或更多个导管之间建立同轴对准。 系统包括两个或更多个主题导管。 这些方法包括使用导管并将其磁耦合以在它们之间建立连续的通道。

    Methods and kits for locally administering an active agent to an interstitial space of a host
    10.
    发明授权
    Methods and kits for locally administering an active agent to an interstitial space of a host 失效
    用于将活性剂本地施用于宿主的间质空间的方法和试剂盒

    公开(公告)号：US06346098B1

    公开(公告)日：2002-02-12

    申请号：US09519950

    申请日：2000-03-07

    申请人： Paul G. Yock ,  Ali H. Hassan ,  Alan Ching Yeun Yeung ,  Andrew Carter ,  Mehrdad Rezaee ,  Niall Herity ,  Sidney Lo ,  Peter J. Fitzgerald

    发明人： Paul G. Yock ,  Ali H. Hassan ,  Alan Ching Yeun Yeung ,  Andrew Carter ,  Mehrdad Rezaee ,  Niall Herity ,  Sidney Lo ,  Peter J. Fitzgerald

    IPC分类号： A61M2500

    CPC分类号： A61K48/00 ,  A61K38/00 ,  A61M37/00

    摘要： Methods are provided for locally administering an agent to a host. Specifically, the subject methods provide for the local administration of an agent to an interstitial space of a host. In the subject methods, an agent is retroinfused into a vessel of a host, typically a vein, under conditions sufficient for the agent to enter an interstitial space of the host proximal to the vessel location into which the agent is retroinfused. In practicing the subject methods, the agent is administered to the host in combination with the production of vascular stress at the site of administration, where the vascular tissue stress is sufficient to provide for transport of the agent from the vascular site of deposition into the target interstitial space. In a preferred embodiment, the agent is retroinfused at a pressure sufficient to provide for mechanical stress on the vessel proximal to the target interstitial space. Also provided are kits for use in practicing the subject methods. The subject invention finds use in the local administration of a variety of different agents for treatment of a variety of different disease or other conditions.

    摘要翻译： 提供用于向宿主局部施用药剂的方法。 具体地，主题方法提供了代理人对主机的间隙空间的本地管理。 在本发明的方法中，在足以使试剂进入宿主的间隙空间的条件下，将试剂逆向灌注到宿主（通常为静脉）的血管中，所述间质空间靠近所述药剂被回输入其中的血管位置。 在实施本发明方法中，将药剂与给药部位的血管应激的产生相结合地施用于宿主，其中血管组织应激足以提供将药物从血管沉积部位输送到靶 间隙空间 在优选的实施方案中，所述试剂在足以在靠近所述靶间质空间的血管上提供机械应力的压力下进行回灌。 还提供了用于实践主题方法的套件。 本发明用于局部施用各种不同的药剂以治疗各种不同的疾病或其他病症。