Abstract:
Electrical activity propagation along an electrode array within a cardiac chamber is reconstructed. Signals are sampled from the electrode array including signals from a channel of interest. An N-dimensional signal vector is then constructed using signals from N neighboring channels referenced to the channel of interest. A change in the N-dimensional signal vector over time is then determined and compared to a predetermined threshold to establish whether local activation has occurred on the channel of interest.
Abstract:
At least some embodiments of the present disclosure are directed to an electroporation ablation device having a first catheter and a second catheter. The first catheter comprises one or more first electrodes and has a first surface area. The second catheter comprises one or more second electrodes and has a second surface area. When the electroporation ablation device is in operation for ablating a target tissue, the first catheter is configured to be disposed in an extracardiac location and anatomically proximate to the target tissue, the second catheter is configured to be disposed at an intracardiac location proximate to the target tissue, and the electroporation ablation device is configured to generate an electric field between the one or more first electrodes and the one or more second electrodes with electric field strength sufficient to ablate the target tissue via irreversible electroporation.
Abstract:
Medical devices and methods for making and using medical devices are disclosed. An example system for mapping the electrical activity of the heart includes a catheter shaft. The catheter shaft includes a plurality of electrodes including a first and a second electrode. The system also includes a processor. The processor is capable of collecting a first signal corresponding to a first electrode over a time period and generating a first time-frequency distribution corresponding to the first signal. The first time-frequency distribution includes a first dominant frequency value representation occurring at one or more first base frequencies. The processor is also capable of applying a filter to the first signal or derivatives thereof to determine whether the first dominant frequency value representation includes a single first dominant frequency value at a first base frequency or two or more first dominant frequency values at two or more base frequencies.
Abstract:
Methods and systems for cardiac mapping are disclosed. An example system includes a catheter shaft with one or more electrodes coupled to a distal end of the catheter shaft. Electrodes sense electrical signals at anatomical locations within a heart. A processor coupled to the catheter shaft acquires electrogram signals of the heart using the electrodes. Each electrogram signal relates to three-dimensional positional data corresponding to the anatomical locations. The processor also store the electrogram signals of the heart corresponding to electrical activities sensed at corresponding anatomical locations, calculate an activation recovery interval associated with each of the corresponding anatomical locations, determine spatial gradient data of the activation recovery interval based on a distance between at least two neighboring anatomical locations. The system also includes a display device to display a three-dimensional graphical representation of the spatial gradient data between the at least two neighboring anatomical.
Abstract:
Methods and systems for cardiac mapping are disclosed. An example system includes a catheter shaft with one or more electrodes coupled to a distal end of the catheter shaft. Electrodes sense electrical signals at anatomical locations within a heart. A processor coupled to the catheter shaft acquires electrogram signals of the heart using the electrodes. Each electrogram signal relates to three-dimensional positional data corresponding to the anatomical locations. The processor also store the electrogram signals of the heart corresponding to electrical activities sensed at corresponding anatomical locations, calculate an activation recovery interval associated with each of the corresponding anatomical locations, determine spatial gradient data of the activation recovery interval based on a distance between at least two neighboring anatomical locations. The system also includes a display device to display a three-dimensional graphical representation of the spatial gradient data between the at least two neighboring anatomical.
Abstract:
Embodiments of the present invention facilitate real-time ablation lesion characteristic analysis. In an embodiment, an electrophysiology system comprises a catheter, a signal generator and a mapping processor. The catheter includes a flexible catheter body having a distal portion and a plurality of electrodes disposed on the distal portion. The signal generator is configured to generate an electrical signal by driving one or more currents between a first set of the plurality of electrodes, wherein a second set of the plurality of electrodes is configured to obtain an impedance measurement based on the electrical signal. Furthermore, the mapping processor configured to: receive the impedance measurement from the second set of electrodes; determine at least one impedance metric; and determine, based on the at least one impedance metric, a likelihood of an occurrence of a steam pop.
Abstract:
An electrophysiology system includes a catheter having a flexible catheter body with a distal portion; and electrodes disposed on the distal portion. The system includes a signal generator configured to generate an electrical signal by driving one or more currents between a first set of the electrodes, where a second set of the electrodes is configured to obtain an impedance measurement based on the electrical signal. A mapping processor is configured to receive the impedance measurement from the second set of electrodes; determine at least one impedance metric; and determine at least one lesion characteristic based on the at least one impedance metric.
Abstract:
Electrical activity propagation along an electrode array within a cardiac chamber is reconstructed. Signals are sampled from the electrode array and the signals are plotted in multi-dimensional space with each axis corresponding to a channel in the electrode array. An excursion direction of global activation in the multi-dimensional space is estimated and a change in vectors of the sampled signals over time is determined. Signals with vectors that change over time in the excursion direction are suppressed.
Abstract:
A system and method for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of electrodes disposed in or near the anatomical structure. A most recent intrinsic event at a selected time is determined based on the sensed activation signals and a persistent display of relevant characteristics is generated based on the sensed activation signals of the most recent intrinsic event. The persistent display is updated upon detection of a subsequent intrinsic event.
Abstract:
A catheter system includes a mapping catheter including a plurality of mapping electrodes, each mapping electrode configured to sense signals associated with an anatomical structure. The catheter system further includes a processor operatively coupled to the plurality of mapping electrodes and configured to receive the signals sensed by the plurality of mapping electrodes, characterize the signals sensed by the plurality of mapping electrodes based on amplitudes of the sensed signals, and generate an output of a quality of contact of the plurality of mapping electrodes with the anatomical structure based on the signal characterization.