Systems, apparatuses and methods for delivery of ablative energy to tissue

    公开(公告)号:US11589921B2

    公开(公告)日:2023-02-28

    申请号:US16921654

    申请日:2020-07-06

    Inventor: Raju Viswanathan

    Abstract: A system includes a pulse waveform generator and an ablation device coupled to the pulse waveform generator. The ablation device includes at least one electrode configured for ablation pulse delivery to tissue during use. The pulse waveform generator is configured to deliver voltage pulses to the ablation device in the form of a pulsed waveform. The pulsed waveform can include multiple levels of hierarchy, and multiple sets of electrodes can be activated such that their pulsed delivery is interleaved with one another.

    Epicardial ablation catheter
    22.
    发明授权

    公开(公告)号:US12274491B2

    公开(公告)日:2025-04-15

    申请号:US17246995

    申请日:2021-05-03

    Abstract: Systems, devices, and methods for electroporation ablation therapy are disclosed herein, with a cinch device for positioning an ablation catheter relative to tissue during a cardiac ablation procedure. In some embodiments, a distal end of a first device may be advanced into a proximal end of a first lumen of a second device. The first device may be advanced from a distal end of the first lumen and the first device may be looped around tissue of a patient. The first device may be advanced into a distal end of a second lumen of the second device. The distal end of the first device may be advanced from a proximal end of the second lumen. The proximal and distal ends of the first device may be advanced away from a proximal end of the second device to increase contact between the first device and the tissue.

    Method and apparatus for rapid and selective tissue ablation with cooling

    公开(公告)号:US11622803B2

    公开(公告)日:2023-04-11

    申请号:US16838617

    申请日:2020-04-02

    Abstract: Systems, tools and methods are disclosed for the selective and rapid application of DC voltage to drive irreversible electroporation, with the system controller capable of being configured to apply voltages to independently selected subsets of electrodes and capable of generating at least one control signal to maintain the temperature near an electrode head within a desired range of values. Electrode clamp devices are also disclosed for generating electric fields to drive irreversible electroporation while modulating temperature to elevate the irreversible electroporation threshold utilizing a variety of means such as cooling fluid or solid state thermoelectric heat pumps.

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