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    Method and apparatus for uniformly crimping a stent onto a catheter
    21.
    发明授权
    Method and apparatus for uniformly crimping a stent onto a catheter 失效
    将支架均匀地压接在导管上的方法和装置

    公开(公告)号：US5974652A

    公开(公告)日：1999-11-02

    申请号：US72925

    申请日：1998-05-05

    申请人： Richard M. Kimes ,  Michael S. Mirizzi

    发明人： Richard M. Kimes ,  Michael S. Mirizzi

    IPC分类号： A61F2/06 ,  A61F2/84 ,  A61M29/00 ,  B23P11/00 ,  B23P19/02

    CPC分类号： A61F2/958 ,  A61F2002/9522 ,  Y10T29/49927 ,  Y10T29/53952 ,  Y10T29/53987 ,  Y10T29/53996

    摘要： A stent crimping tool for firmly and uniformly crimping a stent onto a balloon catheter is constructed from a crimping section holding the stent and the balloon catheter therein, wherein the crimping is actuated by a shaft having an input end and an output end, engaging the crimping section at the output end. The shaft has a detent formed into the input end. A gripping member has an internal cavity to receive the input end, and includes a hole proximate to the shaft, wherein a ball bearing and a compression spring are located within the hole to bias the ball bearing toward the shaft and to engage the detent. When a torque is applied to the gripping member, it is transmitted through the ball bearing to the shaft; if the torque exceeds a predetermined magnitude, it overcomes the force of the spring on the ball bearing causing the bearing to slide out of the detent thereby disconnecting the applied torque from the shaft. The crimping section can be a rubber tube having a lumen holding the stent and catheter. When the shaft compresses the rubber tube as it advances, the lumen collapses and crimps the stent onto the catheter. In another embodiment, the crimping section is a coiled filament suspended at both ends and having an axial space holding the stent and catheter. Rotating the shaft twists the filament which in turn constricts and crimps the stent onto the catheter.

    摘要翻译： 用于将支架牢固且均匀地压接在球囊导管上的支架压接工具由将支架和气囊导管保持在其中的压接部分构成，其中，压接由具有输入端和输出端的轴致动， 在输出端。 轴具有形成输入端的制动器。 夹持构件具有内部空腔以容纳输入端，并且包括靠近轴的孔，其中球轴承和压缩弹簧位于孔内以将球轴承朝向轴偏压并接合止动件。 当扭矩施加到夹持构件时，其通过滚珠轴承传递到轴; 如果扭矩超过预定的大小，则它克服了滚珠轴承上的弹簧的力，导致轴承滑出制动器，从而将施加的扭矩与轴断开。 卷曲部可以是具有保持支架和导管的内腔的橡胶管。 当轴在橡胶管前进时压缩橡胶管时，管腔将支架折叠并卷曲到导管上。 在另一个实施例中，卷曲部分是悬挂在两端并具有保持支架和导管的轴向空间的卷绕细丝。 旋转轴扭转细丝，其又将支架收缩并卷曲到导管上。

    Occlusive implant delivery devices and associated methods
    22.
    发明授权
    Occlusive implant delivery devices and associated methods 有权
    闭塞植入物输送装置及相关方法

    公开(公告)号：US09060773B2

    公开(公告)日：2015-06-23

    申请号：US13328357

    申请日：2011-12-16

    申请人： Hoa D. Nguyen ,  Michael S. Mirizzi ,  Thomas C. Pham

    发明人： Hoa D. Nguyen ,  Michael S. Mirizzi ,  Thomas C. Pham

    IPC分类号： A61F6/06 ,  A61B17/12 ,  A61F2/80

    CPC分类号： A61B17/12022 ,  A61B17/12099 ,  A61B2017/1205 ,  A61F2/80 ,  A61F2002/805

    摘要： The various embodiments simplify the delivery of an occlusive implant to a hollow anatomical structure, such as a fallopian tube. For example, the delivery devices don't need to be retracted manually to deploy the implant. When the devices are activated, stored energy or a powered drive member induces movement of the various components. The operator need only position the distal ends of the devices at the treatment site and then commence deployment by, for example, flipping a switch or changing the position of an activation button. The present embodiments thus increase the efficacy of occlusion procedures by reducing the likelihood of operator error.

    摘要翻译： 各种实施例简化了闭塞植入物到中空解剖结构（例如输卵管）的递送。 例如，递送装置不需要手动缩回以部署植入物。 当设备被激活时，存储的能量或动力驱动构件引起各种部件的移动。 操作者仅需要将设备的远端定位在治疗部位，然后通过例如翻转开关或改变激活按钮的位置来开始部署。 因此，本实施例通过降低操作者错误的可能性来增加遮挡过程的功效。

    Multiple Chamber, Expandable Therapeutic Agent Delivery Device
    23.
    发明申请
    Multiple Chamber, Expandable Therapeutic Agent Delivery Device 审中-公开
    多室，可扩展的治疗剂递送装置

    公开(公告)号：US20150165169A1

    公开(公告)日：2015-06-18

    申请号：US14555819

    申请日：2014-11-28

    申请人： Michael S. Mirizzi

    发明人： Michael S. Mirizzi

    IPC分类号： A61M25/10 ,  A61M25/00

    CPC分类号： A61M25/1002 ,  A61M25/1029 ,  A61M2025/105 ,  A61M2025/1072 ,  A61M2025/1075 ,  A61M2025/1086

    摘要： A device having multiple chambers may be configured to expand to contact a substantial section of an interior wall of a body structure or lumen in order to simultaneously exclude blood or other liquid from a target structure while providing for delivery of a therapeutic agent directly to the interior wall. The expandable device may be manufactured from a plurality of flat sheets of material heat sealed to one another to form an inflation chamber and one, two or more delivery chambers. The sheets may also be bonded to an elongate catheter body having inflation and delivery lumens. The excluding of blood flow and delivery of therapeutic agents are completed by the same device.

    摘要翻译： 具有多个腔室的装置可被构造成膨胀以接触身体结构或内腔的内壁的实质部分，以便同时从目标结构排除血液或其它液体，同时提供将治疗剂直接递送至内部 壁。 可膨胀装置可以由彼此热密封的多个平板材料制成，以形成充气室和一个，两个或更多个输送室。 片材也可以结合到具有充气和输送内腔的细长导管体上。 排除血液流量和治疗剂的输送由相同的装置完成。