公开(公告)号：US12076577B2

公开(公告)日：2024-09-03

申请号：US17543304

申请日：2021-12-06

申请人： Prometheus Therapeutics Inc.

发明人： Baruch B. Lieber ,  John A. Rose

IPC分类号： A61N5/06 ,  A61B1/00 ,  A61B1/05 ,  A61B1/313 ,  A61B17/02 ,  A61B17/12 ,  A61B18/24 ,  A61F2/90 ,  A61M25/00 ,  A61B17/00 ,  A61B17/22 ,  A61B18/00 ,  A61B18/22 ,  A61B90/00 ,  A61F2/82

CPC分类号： A61N5/0601 ,  A61B1/00045 ,  A61B1/00087 ,  A61B1/05 ,  A61B1/3137 ,  A61B17/0218 ,  A61B17/12113 ,  A61B17/12168 ,  A61B17/12172 ,  A61B17/12181 ,  A61B18/24 ,  A61F2/90 ,  A61M25/00 ,  A61N5/062 ,  A61B2017/00292 ,  A61B2017/00557 ,  A61B2017/00778 ,  A61B2017/00907 ,  A61B2017/0225 ,  A61B17/12118 ,  A61B17/12136 ,  A61B17/12186 ,  A61B2017/22067 ,  A61B2018/00029 ,  A61B2018/00404 ,  A61B2018/00416 ,  A61B2018/00589 ,  A61B2018/00982 ,  A61B2018/2238 ,  A61B2018/2261 ,  A61B90/361 ,  A61B2217/007 ,  A61F2002/823 ,  A61F2002/826 ,  A61N2005/0602 ,  A61N2005/0659 ,  A61N2005/0662

摘要： In some embodiments, an apparatus includes a catheter having a catheter body, a light emitter disposed at a distal end of the catheter body, and a fluid conduit coupleable to a source of fluid. The fluid conduit configured to discharge fluid from the source via the conduit and out a distal end of the catheter body. A spacing member is disposed at the distal end of the catheter body and can be moved between a collapsed configuration and an expanded configuration. In the expanded configuration, the spacing member is disposed about the light emitter. The spacing member is at least partially transmissive and/or transflective of light emitted from the light emitter. The apparatus configured to be inserted at least partially into a body lumen, to discharge fluid into the body lumen, and to emit light from the light emitter to illuminate an interior wall of the body lumen.

公开(公告)号：US20240225734A1

公开(公告)日：2024-07-11

申请号：US18408284

申请日：2024-01-09

申请人： Research Development Foundation

发明人： Thomas E. MILNER ,  Marc D. FELDMAN ,  Nitesh KATTA ,  Aleksandra GRUSLOVA ,  Drew R. NOLEN ,  Luis A. DIAZ SANMARTIN ,  Scott JENNEY

IPC分类号： A61B18/24 ,  A61B18/00 ,  A61B18/20 ,  A61B18/22

CPC分类号： A61B18/245 ,  A61B2018/00404 ,  A61B2018/00732 ,  A61B2018/00761 ,  A61B2018/00964 ,  A61B2018/00982 ,  A61B2018/2015 ,  A61B2018/2035 ,  A61B2018/206 ,  A61B2018/207 ,  A61B2018/2211 ,  A61B2018/2222 ,  A61B2018/2244 ,  A61B2018/2261 ,  A61B2018/2272 ,  A61B2018/2294

摘要： Apparatus, systems and methods for fracturing calcium in an artery of a patient. Certain embodiments include a diode laser light source and an optical fiber. In particular embodiments, the optical fiber comprises a polymer or glass optical core, a cladding surrounding the polymer or glass optical core. The optical fiber can comprise one or more emission elements configured to emit electromagnetic energy from the laser light source. The electromagnetic energy can be transmitted through a fluid in the expandable member to fracture the calcium.

公开(公告)号：US11963720B2

公开(公告)日：2024-04-23

申请号：US17871670

申请日：2022-07-22

申请人： ENDO UV TECH

发明人： Brant D. Watson ,  Henry W Van Vurst, IV

IPC分类号： A61B18/24 ,  A61F2/95 ,  A61M25/10 ,  A61B17/22 ,  A61B18/00 ,  A61B18/22

CPC分类号： A61B18/245 ,  A61F2/95 ,  A61M25/104 ,  A61B2017/22068 ,  A61B2017/22079 ,  A61B2018/0041 ,  A61B2018/2261 ,  A61F2002/9528 ,  A61M2205/053

摘要： Described is a method and device for dilating a tubular anatomical structure. The device and method can be useful for extracting a blood clot in an artery of a mammal by concentrically irradiating an inner wall of the occluded artery using an ultraviolet (UV) laser beam delivered by an optical fiber having an external or inverted conical tip. Dilation results from photophysical production and release of nitric oxide from the cells lining the arterial wall when UV laser light is projected as a ring beam onto the inner arterial wall. This “minimal contact persistent dilation system” prepares the artery for safer mechanical extraction by thrombectomy, owing to decrease in friction and dissolution of chemical bonding.

公开(公告)号：US11850442B2

公开(公告)日：2023-12-26

申请号：US17185355

申请日：2021-02-25

申请人： Clinical Laserthermia Systems AB

发明人： Karl-Göran Tranberg ,  Stephan Dymling

IPC分类号： A61N5/06 ,  A61B18/20 ,  A61B18/22 ,  A61B18/00 ,  A61N5/067

CPC分类号： A61N5/0601 ,  A61B2018/00023 ,  A61B2018/00642 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00797 ,  A61B2018/00898 ,  A61B2018/2005 ,  A61B2018/20361 ,  A61B2018/2261 ,  A61N5/067 ,  A61N2005/063 ,  A61N2005/0612 ,  A61N2005/0626 ,  A61N2005/0627 ,  A61N2005/0659

摘要： An apparatus for obtaining an anti-tumour immunologic response by thermotherapy of a treatment lesion covering at least a portion of a tumour is disclosed. The apparatus comprises a heating probe comprising an optical fiber and a cooling catheter. The optical fiber is inserted in the cooling catheter. Further the heating probe has a light emitting area, and the heating probe is interstitially insertable into the tumour of the treatment lesion. The heat probe is internally cooled by a fluid circulating in said catheter. The apparatus further comprises a first thermal sensor member having at least one sensor area. The first thermal sensor member is positionable at a distance from said boundary. The apparatus also comprises a control unit for controlling a power output of said light source based on a measured first temperature.

公开(公告)号：US20230397968A1

公开(公告)日：2023-12-14

申请号：US18456239

申请日：2023-08-25

申请人： Alcon Inc.

发明人： Jochen HORN ,  Alireza MIRSEPASSI ,  Ronald T. SMITH

IPC分类号： A61B90/30 ,  G02B27/42 ,  G02B27/14 ,  G02B3/00 ,  A61F9/008 ,  A61B18/24 ,  A61B18/20

CPC分类号： A61B90/30 ,  G02B27/425 ,  G02B27/14 ,  G02B3/0087 ,  A61F9/00823 ,  A61B18/24 ,  A61B18/20 ,  A61F9/00821 ,  A61B2090/306 ,  A61B2018/2261

摘要： Systems and methods for creating multi-spot laser light beams, multiplexing an illumination light and the multi-spot laser light beams, and delivering the multiplexed light to a surgical handpiece via a multi-core optical fiber cable.

公开(公告)号：US11786305B2

公开(公告)日：2023-10-17

申请号：US17182304

申请日：2021-02-23

申请人： OLYMPUS CORPORATION

发明人： Toshiaki Suzuki

IPC分类号： A61B18/20 ,  A61B18/24 ,  A61B18/00 ,  A61B18/22

CPC分类号： A61B18/24 ,  A61B2018/00517 ,  A61B2018/206 ,  A61B2018/2261

摘要： A light treatment system includes: a probe configured to be inserted into a bladder, the probe including an optical fiber, and a diffuser that is provided at a distal end of the optical fiber, the diffuser being configured to emit the light from a surface of the cylindrical shape in a diffused manner; a balloon catheter into which the probe is inserted, the balloon catheter being configured to be inserted into the bladder, the balloon catheter including a distal end portion that is to be spherically dilated in the bladder; and a liquid that includes light scattering particles and fills inside of the distal end portion when the distal end portion has been dilated, the liquid having an equivalent scattering coefficient μ′s equal to or larger than 5/R, where R is a maximum radius of the distal end portion that has been dilated.

公开(公告)号：US11684420B2

公开(公告)日：2023-06-27

申请号：US16094137

申请日：2017-05-05

申请人： EXIMO MEDICAL LTD

发明人： Ilan Ben Oren ,  Yoel Zabar ,  Oren Meshulam Stern

IPC分类号： A61B18/24 ,  A61B18/14 ,  A61B18/00 ,  A61B18/22 ,  A61B34/30

CPC分类号： A61B18/24 ,  A61B18/1492 ,  A61B34/30 ,  A61B2018/0016 ,  A61B2018/0019 ,  A61B2018/0066 ,  A61B2018/00208 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00601 ,  A61B2018/00607 ,  A61B2018/00642 ,  A61B2018/00904 ,  A61B2018/00982 ,  A61B2018/2211 ,  A61B2018/2261 ,  A61B2018/2272 ,  A61B2034/301

摘要： There is provided herein a catheter for resecting an undesired tissue from a body of a subject, the catheter comprising a tip section in a shape of a cylinder or a cylinder's sector having a central longitudinal axis, the tip section comprising: a central longitudinal lumen; a first set of optical fibers configured to transmit laser radiation outside a distal extremity of the tip section, in a direction parallel to the central longitudinal axis; a second set of optical fibers configured to transmit laser radiation, transversely to the central longitudinal axis; wherein the first set of optical fibers and the second set of optical fibers are selectively operable to resect and/or ablate the undesired tissue.

公开(公告)号：US09855100B2

公开(公告)日：2018-01-02

申请号：US15243609

申请日：2016-08-22

申请人： The Spectranetics Corporation

发明人： Robert Splinter ,  Robert L. Carver ,  Ted A. Giem ,  Kevin D. Taylor ,  Clint Fix

IPC分类号： A61B18/20 ,  A61B18/24 ,  A61B18/22 ,  A61B18/00

CPC分类号： A61B18/24 ,  A61B2018/00023 ,  A61B2018/00577 ,  A61B2018/2261

摘要： A light-diverting catheter tip is provided according to embodiments disclosed herein. The light-diverting catheter tip may be coupled with the distal tip of a laser catheter and divert at least a portion of the light exiting the distal tip of the laser catheter such that the spot size of the laser beam on an object after exiting the catheter tip is larger than the spot size of the light entering the catheter without the catheter tip. The catheter tip may be removably coupled with the catheter or constructed as part of the catheter. In other embodiments, the catheter tip may conduct fluid and/or divert fluid at the tip of the laser catheter.

公开(公告)号：US20170361122A1

公开(公告)日：2017-12-21

申请号：US15539295

申请日：2015-12-18

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

发明人： Claude CHABROL ,  Alim-Louis BENABID

IPC分类号： A61N5/06 ,  A61B18/00 ,  A61B18/22 ,  A61B17/00

CPC分类号： A61N5/0601 ,  A61B2017/00221 ,  A61B2017/00323 ,  A61B2017/00331 ,  A61B2018/00148 ,  A61B2018/00166 ,  A61B2018/00446 ,  A61B2018/2238 ,  A61B2018/2261 ,  A61B2018/2272 ,  A61B2217/005 ,  A61B2217/007 ,  A61B2218/002 ,  A61B2218/007 ,  A61N5/0618 ,  A61N5/0622 ,  A61N2005/0628 ,  A61N2005/063 ,  A61N2005/0659

摘要： An implantable device for optically stimulating a brain of a human being or animal, including: a multi-channel biocompatible catheter including a plurality of channels extending substantially parallel to each other relative to a longitudinal axis of the multi-channel catheter; a light guide, extending into one channel, for optically stimulating the brain, the multi-channel catheter acting as a sheath totally enveloping the light guide; a functional element, extending into another channel, to measure light injected into a surrounding medium at a distal end of the light guide and/or an element acting on the shape of the multi-channel catheter.

公开(公告)号：US09782222B2

公开(公告)日：2017-10-10

申请号：US12604815

申请日：2009-10-23

申请人： David R. Hennings ,  Mitchell P. Goldman ,  Robert A. Weiss ,  Eric B. Taylor ,  Don Johnson

发明人： David R. Hennings ,  Mitchell P. Goldman ,  Robert A. Weiss ,  Eric B. Taylor ,  Don Johnson

IPC分类号： A61N5/067 ,  A61B18/24 ,  A61B17/00 ,  A61B18/00 ,  A61B18/22 ,  A61B90/00

CPC分类号： A61B18/24 ,  A61B2017/00084 ,  A61B2018/00005 ,  A61B2018/00196 ,  A61B2018/2261 ,  A61B2090/036

摘要： This invention is an improved method and device for treating varicose veins 200 or the greater saphenous vein 202. The method comprises the use of infrared laser radiation in the region of 1.2 to 1.8 um in a manner from inside the vessel 200 or 202 such that the endothelial cells of the vessel wall 704 are damaged and collagen fibers in the vessel wall 704 are heated to the point where they permanently contract, the vessel 200 or 202 is occluded and ultimately resorbed. The device includes a laser 102 delivered via a fiber optic catheter 300 that may have frosted or diffusing fiber tips 308. A motorized pull-back device 104 is used, and a thermal sensor 600 may be used to help control the power required to maintain the proper treatment temperature.