公开(公告)号：US12295842B2

公开(公告)日：2025-05-13

申请号：US18535242

申请日：2023-12-11

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Asher L. Metchik ,  Thanh V. Nguyen ,  Raz Biran ,  Arvin T. Chang ,  Tarannum Ishaq Gutierrez ,  Jeff Lindstrom

IPC: A61F2/24 ,  A61F2/00 ,  A61F2/95

Abstract: A method for retrieving a previously inserted prosthetic valve is disclosed. In one example, a loader assembly is inserted through a hub of a delivery sheath device. The delivery sheath device includes an expandable sheath that extends into a blood vessel of a patient. The loader assembly is advanced in a distal direction until a distal section of the loader assembly extends into the expandable sheath which is attached to a distal end of the hub. The distal section has a larger inner diameter than a middle tube section of the loader assembly. A delivery catheter is retracted to move a prosthetic valve attached thereto in a proximal direction until the prosthetic valve is received within the distal section. The loader assembly and the delivery catheter are removed from a proximal end of the hub while the prosthetic valve is retained within the distal section.

公开(公告)号：US20210038384A1

公开(公告)日：2021-02-11

申请号：US17077673

申请日：2020-10-22

Applicant: Edwards Lifesciences Corporation

Inventor： Duy Nguyen ,  Kim D. Nguyen ,  Thanh V. Nguyen

IPC: A61F2/24

Abstract: Embodiments of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such embodiments can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some embodiments can include a sheath with an intermediate layer including an expandable mesh tube, an outer polymeric layer extending over at least a portion of the intermediate layer, and an inner polymeric layer extending within the intermediate layer. The intermediate layer and the inner polymeric layer are configured to establish an enlarged lumen to allow passage of the prosthetic heart valve.

公开(公告)号：US20180280137A1

公开(公告)日：2018-10-04

申请号：US15997587

申请日：2018-06-04

Applicant: Edwards Lifesciences Corporation

Inventor： Duy Nguyen ,  Kim D. Nguyen ,  Thanh V. Nguyen

IPC: A61F2/24 ,  A61B90/00

Abstract: Embodiments of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such embodiments can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some embodiments can include a sheath with inner and outer layers, where a folded portion of the inner layer extends through a slit in the outer layer and a portion of the outer layer overlaps the folded portion of the inner layer. Some embodiments include an elastic outer cover positioned outside the outer layer. Embodiments of the present expandable sheath can avoid the need for multiple insertions for the dilation of the vessel, thus offering advantages over prior art introducer sheaths.

公开(公告)号：US20180125656A1

公开(公告)日：2018-05-10

申请号：US15868741

申请日：2018-01-11

Applicant: Edwards Lifesciences Corporation

Inventor： George Bakis ,  Thanh V. Nguyen ,  Ly Th Phan ,  Asher L. Metchik

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2439

Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.

公开(公告)号：US09867700B2

公开(公告)日：2018-01-16

申请号：US14283056

申请日：2014-05-20

Applicant: Edwards Lifesciences Corporation

Inventor： George Bakis ,  Thanh V. Nguyen ,  Ly T. Phan ,  Asher L. Metchik

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2439

Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.

公开(公告)号：US20170049567A1

公开(公告)日：2017-02-23

申请号：US15238605

申请日：2016-08-16

Applicant: Edwards Lifesciences Corporation

Inventor： Asher L. Metchik ,  Thanh V. Nguyen ,  Raz Biran ,  Arvin T. Chang ,  Taranum Nagpurwala ,  Jeff Lindstrom

IPC: A61F2/24 ,  B21D39/04 ,  A61F2/00

CPC classification number: A61F2/2433 ,  A61F2/0095 ,  A61F2/2436 ,  A61F2002/9522 ,  A61F2250/0039

Abstract: A loader and method for loading a transcatheter heart valve into a delivery sheath or catheter is described that is also configured to facilitate retrieval of the heart valve back through the delivery sheath while protecting the delivery sheath from damage. Another loader provides for easier crimping and loading of a THV into a delivery sheath or catheter from a storage jar or container. A method for crimping a THV facilitates easier end user preparation of the valve for implantation and reduces the likelihood of tissue deformation in the valve during storage. These devices and methods for deploying THVs simplify the valve replacement procedure.

Abstract translation: 描述了用于将经导管心脏瓣膜装载到输送鞘或导管中的装载器和方法，其还构造成便于通过输送护套回流心脏瓣膜，同时保护输送鞘免受损伤。 另一个装载机可以方便地从储存罐或容器将THV卷曲和装载到输送鞘或导管中。 用于压接THV的方法便于终端用户准备用于植入的阀，并且减少在储存期间阀组织变形的可能性。 这些用于部署THV的设备和方法简化了阀门更换过程。

公开(公告)号：US20160310270A1

公开(公告)日：2016-10-27

申请号：US15057953

申请日：2016-03-01

Applicant: Edwards Lifesciences Corporation

Inventor： Duy Nguyen ,  Kim D. Nguyen ,  Thanh V. Nguyen

IPC: A61F2/24

CPC classification number: A61F2/2427 ,  A61B90/39 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  Y10T156/1026

Abstract: Embodiments of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such embodiments can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some embodiments can include a sheath with inner and outer layers, where a folded portion of the inner layer extends through a slit in the outer layer and a portion of the outer layer overlaps the folded portion of the inner layer. Some embodiments include an elastic outer cover positioned outside the outer layer. Embodiments of the present expandable sheath can avoid the need for multiple insertions for the dilation of the vessel, thus offering advantages over prior art introducer sheaths.

Abstract translation: 可扩张护套的实施例可以与导管组件一起使用以将诸如心脏瓣膜的假体装置引入患者体内。 这样的实施例可以通过允许引导器护套的一部分临时膨胀以适应输送装置来最小化对容器的创伤，然后一旦假肢装置通过就恢复到原始直径。 一些实施例可以包括具有内层和外层的护套，其中内层的折叠部分延伸穿过外层中的狭缝，并且外层的一部分与内层的折叠部分重叠。 一些实施例包括位于外层外部的弹性外盖。 本发明的可扩张护套的实施例可以避免需要多次插入用于扩张容器，从而提供优于现有技术的导引器护套的优点。

公开(公告)号：US20140343670A1

公开(公告)日：2014-11-20

申请号：US14283056

申请日：2014-05-20

Applicant: Edwards Lifesciences Corporation

Inventor： George Bakis ,  Thanh V. Nguyen ,  Ly T. Phan

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2439

Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.

Abstract translation: 本公开的某些实施例提供了一种人造瓣膜（例如，假体心脏瓣膜）和用于经由人类脉管系统将人工瓣膜输送到自然瓣膜部位的瓣膜输送装置。 输送装置特别适合于通过主动脉推进假体心脏瓣膜（即逆行方法），以更换患病的天然主动脉瓣。 在特定实施例中的输送装置被配置成以精确和受控的方式将人造瓣膜从输送护套部署到体内的目标位置。

公开(公告)号：US20240358509A1

公开(公告)日：2024-10-31

申请号：US18770297

申请日：2024-07-11

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： George Bakis ,  Thanh V. Nguyen ,  Ly Th Phan ,  Asher L. Metchik

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2439

Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.

公开(公告)号：US12059348B2

公开(公告)日：2024-08-13

申请号：US16897208

申请日：2020-06-09

Applicant: Edwards Lifesciences Corporation

Inventor： George Bakis ,  Thanh V. Nguyen ,  Ly Th Phan ,  Asher L. Metchik

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2439

Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.