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公开(公告)号：US20170119525A1
公开(公告)日：2017-05-04
申请号：US15403458
申请日：2017-01-11
Applicant: Edwards Lifesciences Corporation
Inventor： Stanton J. Rowe , Larry L. Wood , Henry Bourang , George Bakis , Benjamin Spenser , Netanel Benichou , Assaf Bash , Yaron Keidar
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2445 , A61F2/90 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/0041 , A61F2220/0066 , A61F2220/0075 , A61F2220/0083 , A61F2230/0078 , A61F2250/006 , A61F2250/0098 , A61L27/3625
Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.
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公开(公告)号：US20240358509A1
公开(公告)日：2024-10-31
申请号：US18770297
申请日：2024-07-11
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： George Bakis , Thanh V. Nguyen , Ly Th Phan , Asher L. Metchik
IPC: A61F2/24
CPC classification number: A61F2/2436 , A61F2/2418 , A61F2/2439
Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.
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公开(公告)号：US12059348B2
公开(公告)日：2024-08-13
申请号：US16897208
申请日：2020-06-09
Applicant: Edwards Lifesciences Corporation
Inventor： George Bakis , Thanh V. Nguyen , Ly Th Phan , Asher L. Metchik
IPC: A61F2/24
CPC classification number: A61F2/2436 , A61F2/2418 , A61F2/2439
Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.
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公开(公告)号：US20200237508A1
公开(公告)日：2020-07-30
申请号：US16827612
申请日：2020-03-23
Applicant: Edwards Lifesciences Corporation
Inventor： Alexander J. Siegel , George Bakis
Abstract: The present disclosure pertains to introducer sheaths with an inner liner for percutaneous insertion of a medical device into a patient. The introducer sheaths can further have a tubular layer and an outer layer. The tubular layer can be a metal sleeve having a plurality of slots. The present disclosure also discloses embodiments of catheter-based prosthetic heart valves, including, prosthetic heart valves having sealing members configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted.
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公开(公告)号：US10226338B1
公开(公告)日：2019-03-12
申请号：US16197280
申请日：2018-11-20
Applicant: Edwards Lifesciences Corporation
Inventor： Stanton J. Rowe , Larry L. Wood , Henry Bourang , George Bakis , Benjamin Spenser , Netanel Benichou , Assaf Bash , Yaron Keidar
Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.
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Patent Agency Ranking
公开(公告)号：US20250161036A1
公开(公告)日：2025-05-22
申请号：US19029851
申请日：2025-01-17
Applicant: Edwards Lifesciences Corporation
Inventor： Alexander J. Siegel , George Bakis , Lien-Huong T. Hoang
IPC: A61F2/24 , A61M25/00 , A61M25/01 , A61M25/06 , B29C49/24 , B29C49/26 , B29C63/34 , B29K101/12 , B29K705/00
Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves. In one embodiment, a prosthetic heart valve includes a collapsible and expandable annular frame, a leaflet assembly mounted within the annular frame, a first skirt mounted on the frame, and a second skirt mounted on the frame. The frame includes a plurality of rows of cells. The leaflet assembly includes a plurality of leaflets. Adjacent leaflets are connected to each other to form commissures, each of which is connected to a cell of an outflow row of cells of the frame.
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公开(公告)号：US20200054450A1
公开(公告)日：2020-02-20
申请号：US16666099
申请日：2019-10-28
Applicant: Edwards Lifesciences Corporation
Inventor： Stanton J. Rowe , Larry L. Wood , Henry Bourang , George Bakis , Benjamin Spenser , Netanel Benichou , Assaf Bash , Yaron Keidar
Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.
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公开(公告)号：US10456251B2
公开(公告)日：2019-10-29
申请号：US16298616
申请日：2019-03-11
Applicant: Edwards Lifesciences Corporation
Inventor： Stanton J. Rowe , Larry L. Wood , Henry Bourang , George Bakis , Benjamin Spenser , Netanel Benichou , Assaf Bash , Yaron Keidar
Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.
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公开(公告)号：US20150157455A1
公开(公告)日：2015-06-11
申请号：US14561102
申请日：2014-12-04
Applicant: Edwards Lifesciences Corporation
Inventor： Lien-Huong T. Hoang , Alexander J. Siegel , George Bakis
CPC classification number: A61F2/2418 , A61F2/24 , A61F2/2415 , A61F2/2436 , A61F2/2439 , A61F2/2475 , A61F2210/0076 , A61F2220/0075 , A61F2240/001 , A61F2250/0039 , A61F2250/006 , A61F2250/0069 , B29C63/34 , B29K2101/12 , B29K2705/00
Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves, and in particular, prosthetic heart valves having sealing members configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. The present disclosure also discloses new methods of making an introducer sheath with an inner liner for percutaneous insertion of a medical device into a patient.
Abstract translation: 本公开涉及基于导管的假体心脏瓣膜的具体实施方式，并且特别地，具有密封构件的假体心脏瓣膜被配置为密封假体瓣膜和植入人造瓣膜的天然环带的周围组织之间的界面。 本公开还公开了用于将医疗装置经皮插入患者体内的用于制造具有内衬片的引导器护套的新方法。
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公开(公告)号：US20150105856A1
公开(公告)日：2015-04-16
申请号：US14571141
申请日：2014-12-15
Applicant: Edwards Lifesciences Corporation
Inventor： Stanton J. Rowe , Larry L. Wood , Henry Bourang , George Bakis , Benjamin Spenser , Netanel Benichou , Assaf Bash , Yaron Keidar
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2445 , A61F2/90 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/0041 , A61F2220/0066 , A61F2220/0075 , A61F2220/0083 , A61F2230/0078 , A61F2250/006 , A61F2250/0098 , A61L27/3625
Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be expandable or a non-expandable type.
Abstract translation: 提供了可以在手术过程中快速且容易地植入的心脏瓣膜假体。 假体瓣膜包括部署在治疗部位的支撑结构。 假体瓣膜还包括构造成快速连接到支撑结构的阀构件。 支撑结构可以采取在天然瓣膜部位扩张的支架的形式。 如果需要，天然传单可以保留，并且支架可以用于保持天然瓣膜打开。 在这种情况下，支架可以是球囊可扩张的并且被配置为抵抗天然传单的强大后坐力。 支撑结构设置有用于附接到阀构件的联接装置，从而将阀构件的位置固定在主体中。 阀构件可以是可膨胀型或不可膨胀型。
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