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公开(公告)号:US20170290686A1
公开(公告)日:2017-10-12
申请号:US15605601
申请日:2017-05-25
Applicant: Elixir Medical Corporation
Inventor: Motasim Sirhan , John Yan , Vinayak Bhat , Joseph Paraschac , Brett Cryer , Benjamyn S. Serna
CPC classification number: A61F2/89 , A61F2/2442 , A61F2/90 , A61F2/915 , A61F2002/075 , A61F2002/825 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/91591 , A61F2210/0004 , A61F2210/0014 , A61F2210/0076 , A61F2220/0033 , A61F2220/0091 , A61F2230/0006 , A61F2230/0008 , A61F2230/001 , A61F2230/0069 , A61F2250/0031 , A61F2250/0036 , A61F2250/0048 , A61F2250/0067 , A61F2250/0071
Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.
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公开(公告)号:US20240260984A1
公开(公告)日:2024-08-08
申请号:US18636086
申请日:2024-04-15
Applicant: Elixir Medical Corporation
Inventor: Motasim Sirhan , Vinayak Bhat , Benjamyn Serna , Samit Mustafa , Brett Cryer , Kim Nguyen , John Yan
IPC: A61B17/221 , A61B17/00 , A61B17/22
CPC classification number: A61B17/221 , A61B2017/00358 , A61B2017/0084 , A61B2017/22079 , A61B2017/2212
Abstract: An aspiration catheter for removing clot from a blood vessel includes a catheter body having a scaffold extending distally from a distal end of the body. An aspiration lumen runs from the distal end to a proximal end of the body, and a central clot-receiving passage in the scaffold is contiguous with the aspiration lumen of the catheter body. A vacuum-resistant membrane covers the scaffold and establishes a clot aspiration path from a distal end of the scaffold to a proximal end of the aspiration lumen, in the catheter body so that applying a vacuum to the proximal end of the aspiration lumen can draw clot into the central clot-receiving passage. The scaffold may have a comical configuration, a cylindrical configuration, or a combination thereof, and at least a distal portion of the scaffold is radially expandable from a delivery configuration to an extraction configuration.
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公开(公告)号:US12011184B2
公开(公告)日:2024-06-18
申请号:US17863265
申请日:2022-07-12
Applicant: Elixir Medical Corporation
Inventor: Motasim Sirhan , Benjamyn Serna , Bozena Treadwell , John Yan
CPC classification number: A61B17/22 , A61F2/2418 , A61F2/2436 , A61B2017/00783 , A61B2017/22001 , A61B2017/22051 , A61B2017/22098 , A61F2250/006
Abstract: Balloon catheters, sleeves, cages, and endoluminal prostheses are provided with stress-applying and spacing features coupled to expandable surfaces thereof. The stress-applying features may have blunt and/or rounded contact regions which contact tissue or calcified regions in the vasculature. The contact regions dent or fracture occlusive material on the wall of a vascular lumen and/or patient valve leaflets when expanded. The spacing features permit blood, drug, and contrast perfusion past structures expanded in the vasculature, particularly balloon catheters.
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公开(公告)号:US11654036B2
公开(公告)日:2023-05-23
申请号:US17402357
申请日:2021-08-13
Applicant: Elixir Medical Corporation
Inventor: Motasim Sirhan , Xiaoxia Zheng , Vinayak D. Bhat , John Yan
IPC: A61K31/5377 , A61F2/82 , A61L27/50 , A61L27/54 , A61L31/16 , A61L33/00 , A61L27/20 , A61L27/34 , A61L31/04 , A61L31/10 , A61L33/08 , A61K31/4545 , A61L27/58 , A61F2/844 , A61K31/727 , A61F2/848 , A61K31/4709
CPC classification number: A61F2/844 , A61F2/82 , A61F2/848 , A61K31/4545 , A61K31/4709 , A61K31/5377 , A61K31/727 , A61L27/20 , A61L27/34 , A61L27/507 , A61L27/54 , A61L31/04 , A61L31/042 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L33/08 , A61F2210/0004 , A61F2220/0008 , A61F2250/0035 , A61F2250/0068 , A61L27/58
Abstract: Devices, systems, and methods are provided including a structure having one or more surfaces configured for internal use within a patient's body and one or more therapeutic compositions comprising one or more active substances including a direct factor Xa inhibitor, and a direct factor IIa inhibitor disposed in or on the structure. The structure is configured to be positioned adjacent an injury site in the patient's body. The one or more active substances optionally include an anti-proliferative agent. The therapeutic composition is formulated to release the one or more active substances to the injury site to provide one or more of inhibit clot formation, promote clot dissolution, inhibit or dissolute inflammation, inhibit vessel injury, increase time before clotting, and/or inhibit cell proliferation.
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公开(公告)号:US20210186722A1
公开(公告)日:2021-06-24
申请号:US17195478
申请日:2021-03-08
Applicant: Elixir Medical Corporation
Inventor: Motasim Sirhan , Vinayak Bhat , Joseph Paraschac , Benjamyn Serna , John Yan
Abstract: A system for reshaping a valve annulus includes an elongate template having a length along a longitudinal axis and at least one concavity in a generally lateral direction along said length. The pre-shaped template is positioned against at least a region of an inner peripheral wall of the valve annulus, and at least one anchor on the template is advanced into a lateral wall of the valve annulus to reposition at least one segment of the region of the inner peripheral wall of the valve annulus into said concavity. In this way, a peripheral length of the valve annulus can be foreshortened and/or reshaped to improve coaption of the valve leaflets and/or to eliminate or decrease regurgitation of a valve.
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公开(公告)号:US20210038411A1
公开(公告)日:2021-02-11
申请号:US17073052
申请日:2020-10-16
Applicant: Elixir Medical Corporation
Inventor: Motasim Sirhan , Vinayak Bhat , Joseph Paraschac , Benjamyn Serna , John Yan
Abstract: A system for reshaping a valve annulus includes an elongate template having a length along a longitudinal axis and at least one concavity in a generally lateral direction along said length. The pre-shaped template is positioned against at least a region of an inner peripheral wall of the valve annulus, and at least one anchor on the template is advanced into a lateral wall of the valve annulus to reposition at least one segment of the region of the inner peripheral wall of the valve annulus into said concavity. In this way, a peripheral length of the valve annulus can be foreshortened and/or reshaped to improve coaption of the valve leaflets and/or to eliminate or decrease regurgitation of a valve.
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公开(公告)号:US10786374B2
公开(公告)日:2020-09-29
申请号:US16518657
申请日:2019-07-22
Applicant: Elixir Medical Corporation
Inventor: Motasim Sirhan , John Yan , Vinayak Bhat , Joseph Paraschac , Brett Cryer , Benjamyn Serna
Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.
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公开(公告)号:US20160128849A1
公开(公告)日:2016-05-12
申请号:US14998288
申请日:2015-12-23
Applicant: Elixir Medical Corporation
Inventor: John Yan , Motasim Sirhan , Brett Cryer , Vinayak Bhat
IPC: A61F2/82
CPC classification number: A61F2/82 , A61F2/02 , A61F2/06 , A61F2/07 , A61F2/90 , A61F2210/0004 , A61F2220/0058 , A61F2250/003 , A61F2250/0067 , B23K26/0006 , B23K26/0624 , B23K26/355 , B23K26/382 , B23K26/40 , B23K2101/06 , B23K2103/02 , B23K2103/12 , B23K2103/50
Abstract: Devices and methods are provided for an implantable medical device which is degradable over a clinically relevant period of time. The medical devices may have the form of implants, graft implants, vascular implants, non vascular implants, wound closure implants, sutures, drug delivery implants, biologic delivery implants, urinary tract implants, inter-uterine implants, organ implants, bone implants including bone plates, bone screws, dental implants, spinal disks, or the like. In preferred embodiments, the implantable medical device comprises an implantable luminal prosthesis, such as vascular and non-vascular stents and stents grafts.
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公开(公告)号:US20250073052A1
公开(公告)日:2025-03-06
申请号:US18629632
申请日:2024-04-08
Applicant: Elixir Medical Corporation
Inventor: Motasim Sirhan , John Yan , Vinayak Bhat , Joseph Paraschac , Brett Cryer , Benjamyn Serna
Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provide high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold is typically formed from non-degradable material and will be modified to expand and/or uncage after deployment.
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公开(公告)号:US12076504B2
公开(公告)日:2024-09-03
申请号:US18482711
申请日:2023-10-06
Applicant: Elixir Medical Corporation
Inventor: Motasim Sirhan , Benjamyn Serna , Kim Nguyen , John Yan , Matthew Tyler Surber
CPC classification number: A61M25/0052 , A61M25/0074 , A61M2202/0014
Abstract: An aspiration catheter includes a catheter body having a proximal end, a distal end, and an aspiration lumen therebetween. A distal segment comprising an expandable distal tip of the aspiration catheter comprises a membrane and an expandable supporting structure, such as a scaffold, configured to radially expand the expandable distal tip. The expandable supporting structure may include supporting elements and other features which increase resistance to collapse of the expandable membrane under vacuum or negative pressure applied to aspirate clot through the aspiration lumen in the expanded configuration.
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