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公开(公告)号：US12011378B2
公开(公告)日：2024-06-18
申请号：US18187583
申请日：2023-03-21
Applicant: Elixir Medical Corporation
Inventor： Motasim Sirhan , John Yan , Vinayak Bhat , Joseph Paraschac , Brett Cryer , Benjamyn Serna
CPC classification number: A61F2/89 , A61F2/90 , A61F2/915 , A61F2002/075 , A61F2/2442 , A61F2002/825 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/91591 , A61F2210/0004 , A61F2210/0014 , A61F2210/0076 , A61F2220/0033 , A61F2220/0091 , A61F2230/0006 , A61F2230/0008 , A61F2230/001 , A61F2230/0069 , A61F2250/0031 , A61F2250/0036 , A61F2250/0048 , A61F2250/0067 , A61F2250/0071
Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provide high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold is typically formed from non-degradable material and will be modified to expand and/or uncage after deployment.
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公开(公告)号：US20230201014A1
公开(公告)日：2023-06-29
申请号：US18178377
申请日：2023-03-03
Applicant: Elixir Medical Corporation
Inventor： Motasim Sirhan , John Yan , Vinayak Bhat , Joseph Paraschac , Brett Cryer , Benjamyn Serna
CPC classification number: A61F2/89 , A61F2/915 , A61F2/90 , A61F2002/075
Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provide high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold is typically formed from non-degradable material and will be modified to expand and/or uncage after deployment.
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公开(公告)号：US20230149035A1
公开(公告)日：2023-05-18
申请号：US18156921
申请日：2023-01-19
Applicant: Elixir Medical Corporation
Inventor： Motasim Sirhan , Vinayak Bhat , Benjamyn Serna , Brett Cryer , Kim Nguyen , John Yan
IPC: A61B17/221 , A61M1/00 , A61M25/00
CPC classification number: A61B17/221 , A61M1/77 , A61M25/005 , A61B2017/22079
Abstract: Clot aspiration systems intended for removing clot from a blood vessel include an aspiration assembly which will have two or more of the following components: an aspiration catheter, an inner catheter, an intermediate catheter, and an outer catheter, the latter typically being a guiding or other sheath. A transition structure is coupled to a distal end of the aspiration assembly to cover or fill an open distal end of one or more of the components of the aspiration assembly. The transition structure may be configured to facilitate introduction of the aspiration catheter into the patient's vasculature and/or advancement of the aspiration catheter through the vasculature to a target site, such as a cerebral target site which may be occluded with clot, thrombus, or other occlusive material.
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公开(公告)号：US10973662B2
公开(公告)日：2021-04-13
申请号：US17073052
申请日：2020-10-16
Applicant: Elixir Medical Corporation
Inventor： Motasim Sirhan , Vinayak Bhat , Joseph Paraschac , Benjamyn Serna , John Yan
Abstract: A system for reshaping a valve annulus includes an elongate template having a length along a longitudinal axis and at least one concavity in a generally lateral direction along said length. The pre-shaped template is positioned against at least a region of an inner peripheral wall of the valve annulus, and at least one anchor on the template is advanced into a lateral wall of the valve annulus to reposition at least one segment of the region of the inner peripheral wall of the valve annulus into said concavity. In this way, a peripheral length of the valve annulus can be foreshortened and/or reshaped to improve coaption of the valve leaflets and/or to eliminate or decrease regurgitation of a valve.
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公开(公告)号：US20200146854A1
公开(公告)日：2020-05-14
申请号：US16740172
申请日：2020-01-10
Applicant: Elixir Medical Corporation
Inventor： Motasim Sirhan , Vinayak Bhat , Joseph Paraschac , Benjamyn Serna , John Yan , Brett Cryer
Abstract: A system for reshaping a valve annulus includes an elongate template having a length along a longitudinal axis and at least one concavity in a generally lateral direction along said length. The pre-shaped template is positioned against at least a region of an inner peripheral wall of the valve annulus, and at least one anchor on the template is advanced into a lateral wall of the valve annulus to reposition at least one segment of the region of the inner peripheral wall of the valve annulus into said concavity. In this way, a peripheral length of the valve annulus can be foreshortened and/or reshaped to improve coaption of the valve leaflets and/or to eliminate or decrease regurgitation of a valve.
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Patent Agency Ranking
公开(公告)号：US10383750B1
公开(公告)日：2019-08-20
申请号：US16356933
申请日：2019-03-18
Applicant: Elixir Medical Corporation
Inventor： Motasim Sirhan , John Yan , Vinayak Bhat , Joseph Paraschac , Brett Cryer , Benjamyn Serna
Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.
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公开(公告)号：US10350093B2
公开(公告)日：2019-07-16
申请号：US14998288
申请日：2015-12-23
Applicant: Elixir Medical Corporation
Inventor： John Yan , Motasim Sirhan , Brett Cryer , Vinayak Bhat
IPC: A61F2/82 , A61F2/02 , A61F2/06 , A61F2/07 , B23K26/00 , B23K26/40 , B23K26/0622 , B23K26/382 , B23K26/352 , A61F2/90 , B23K101/06 , B23K103/02 , B23K103/12 , B23K103/00
Abstract: Devices and methods are provided for an implantable medical device which is degradable over a clinically relevant period of time. The medical devices may have the form of implants, graft implants, vascular implants, non vascular implants, wound closure implants, sutures, drug delivery implants, biologic delivery implants, urinary tract implants, inter-uterine implants, organ implants, bone implants including bone plates, bone screws, dental implants, spinal disks, or the like. In preferred embodiments, the implantable medical device comprises an implantable luminal prosthesis, such as vascular and non-vascular stents and stents grafts.
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公开(公告)号：US20230293540A1
公开(公告)日：2023-09-21
申请号：US18179160
申请日：2023-03-06
Applicant: Elixir Medical Corporation
Inventor： John Yan , Xiaoxia Zheng , Vinayak D. Bhat , Motasim Sirhan , Margaret Wong , Blaine Bueche
IPC: A61K31/5377 , A61K9/00 , A61K31/4545 , A61K47/10 , A61P27/02
CPC classification number: A61K31/5377 , A61K9/0019 , A61K9/0048 , A61K31/4545 , A61K47/10 , A61P27/02
Abstract: Devices, formulations, compositions, and methods are provided for inhibiting an inflammatory ophthalmic disease or eye condition in a patient. A therapeutic composition comprising a direct factor Xa inhibitor and/or a direct factor II inhibitor is provided. A therapeutically effective dose of the therapeutic composition is delivered to a site of the inflammatory ophthalmic disease or condition in the patient’s eye(s). The therapeutic composition may be formulated for delivery to the patient by via injection, an implant, an eye drop, an emulsion, a suspension, an ointment, a nanomicelle, a nanoparticle, a nanosuspension, a liposome, an in-situ gel, a contact lens, or a microneedle or the like. The therapeutic composition may include one or more additional therapeutically active substances and/or one or more additional pharmaceutical agents. The one or more additional therapeutically active substances and/or one or more additional pharmaceutical agents may be delivered together with the direct factor Xa inhibitor and/or direct factor IIa inhibitor, or separately from the direct factor Xa inhibitor and/or direct factor IIa inhibitor.
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公开(公告)号：US20230190499A1
公开(公告)日：2023-06-22
申请号：US18106452
申请日：2023-02-06
Applicant: Elixir Medical Corporation
Inventor： Motasim Sirhan , Xiaoxia Zheng , Vinayak D. Bhat , John Yan
IPC: A61F2/844 , A61L31/10 , A61K31/727 , A61L27/54 , A61K31/4545 , A61F2/82 , A61K31/4709 , A61F2/848 , A61L31/04 , A61L33/08 , A61K31/5377 , A61L31/16 , A61L27/20 , A61L27/50 , A61L33/00 , A61L27/34 , A61L27/58
CPC classification number: A61F2/844 , A61L31/10 , A61K31/727 , A61L27/54 , A61K31/4545 , A61F2/82 , A61K31/4709 , A61F2/848 , A61L31/042 , A61L33/08 , A61K31/5377 , A61L31/16 , A61L27/20 , A61L27/507 , A61L33/0011 , A61L27/34 , A61L31/04 , A61F2220/0008 , A61L27/58 , A61F2250/0068 , A61F2250/0035 , A61F2210/0004
Abstract: Devices, systems, and methods are provided including a structure having one or more surfaces configured for internal use within a patient's body and one or more therapeutic compositions comprising one or more active substances including a direct factor Xa inhibitor, and a direct factor IIa inhibitor disposed in or on the structure. The structure is configured to be positioned adjacent an injury site in the patient's body. The one or more active substances optionally include an anti-proliferative agent. The therapeutic composition is formulated to release the one or more active substances to the injury site to provide one or more of inhibit clot formation, promote clot dissolution, inhibit or dissolute inflammation, inhibit vessel injury, increase time before clotting, and/or inhibit cell proliferation.
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公开(公告)号：US11622872B2
公开(公告)日：2023-04-11
申请号：US16786736
申请日：2020-02-10
Applicant: Elixir Medical Corporation
Inventor： Motasim Sirhan , John Yan , Vinayak Bhat , Joseph Paraschac , Brett Cryer , Benjamyn Serna
Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provide high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold is typically formed from non-degradable material and will be modified to expand and/or uncage after deployment.
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