公开(公告)号：US07264629B2

公开(公告)日：2007-09-04

申请号：US10422363

申请日：2003-04-23

申请人： Guillermo O. Simkin ,  Anna M. Richter ,  David W. C. Hunt ,  John Robert North ,  Peter Lutwyche ,  Ronald Erwin Boch ,  Jean-Marie Houle

发明人： Guillermo O. Simkin ,  Anna M. Richter ,  David W. C. Hunt ,  John Robert North ,  Peter Lutwyche ,  Ronald Erwin Boch ,  Jean-Marie Houle

IPC分类号： A61N5/06 ,  A61B18/18

CPC分类号： A61K8/4913 ,  A61K9/0014 ,  A61K9/0019 ,  A61K31/40 ,  A61K31/409 ,  A61K31/555 ,  A61K41/0061 ,  A61K41/0071 ,  A61K41/0076 ,  A61K47/10 ,  A61K2800/434 ,  A61K2800/81 ,  A61N5/0617 ,  A61N5/062 ,  A61Q7/00

摘要： Photodynamic therapy (PDT) is used to stimulate and/or restore hair growth in areas of hair loss. Methods and compositions relating to PDT treatment for alopecia are disclosed. In light of PDT use to remove unwanted hair by inactivating or destroying hair follicles or destroying the tissue feeding the hair follicles, such methods and compositions relate to a surprising and unexpected discovery. PDT permits a means to treat conditions relating to hair loss such as androgenic alopecia, alopecia areata and drug-induced alopecia.

摘要翻译： 光动力疗法（PDT）用于刺激和/或恢复脱发区域的头发生长。 公开了与脱发的PDT治疗相关的方法和组合物。 鉴于PDT，通过灭活或破坏毛囊或破坏喂养毛囊的组织来去除不需要的毛发，这种方法和组合物涉及惊人的和意想不到的发现。 PDT允许治疗与脱发有关的病症的手段，例如雄激素性脱发，斑秃和药物诱发的脱发。

公开(公告)号：US5736563A

公开(公告)日：1998-04-07

申请号：US555235

申请日：1995-11-08

申请人： Anna M. Richter

发明人： Anna M. Richter

IPC分类号： A61K41/00 ,  A61K31/365 ,  A61K31/40 ,  A61K31/409 ,  A61N5/06 ,  A61P31/00 ,  A61P31/12 ,  A61P35/02 ,  A61P43/00 ,  A61K31/41

CPC分类号： A61K41/0071 ,  A61K31/365 ,  A61K31/40 ,  A61K31/409

摘要： A method destroys or impairs target cells that have selectively accumulated a photosensitizing agent. The target cells are in the bloodstream of an intact animal, which bloodstream and animal further contain non-target cells. Radiation is applied transcutaneously to at least a portion of the intact animal at an intensity effective to impair or destroy selectively the target cells and to leave non-target cells relatively unimpaired. Target cells include leukemia cells, virus-containing cells, parasite-containing cells, and microorganisms such as bacteria, parasites and free viruses.

公开(公告)号：US5484803A

公开(公告)日：1996-01-16

申请号：US384440

申请日：1995-02-02

申请人： Anna M. Richter

发明人： Anna M. Richter

IPC分类号： A61K41/00 ,  A61K31/365 ,  A61K31/40 ,  A61K31/409 ,  A61N5/06 ,  A61P31/00 ,  A61P31/12 ,  A61P35/02 ,  A61P43/00 ,  A61K31/41

CPC分类号： A61K41/0071 ,  A61K31/365 ,  A61K31/40 ,  A61K31/409

摘要： A method destroys or impairs target cells that have selectively accumulated a photosensitizing agent. The target cells are in the bloodstream of an intact animal, which bloodstream and animal further contain non-target cells. Radiation is applied transcutaneously to at least a portion of the intact animal at an intensity effective to impair or destroy selectively the target cells and to leave non-target cells relatively unimpaired. Target cells include leukemia cells, virus-containing cells, parasite-containing cells, and microorganisms such as bacteria, parasites and free viruses.

摘要翻译： 一种方法可以破坏或损害选择性地积累光敏剂的靶细胞。 靶细胞在完整动物的血液中，血液和动物进一步含有非靶细胞。 将辐射以完整动物的至少一部分经皮肤施用，其强度有效地损害或破坏靶细胞并使非目标细胞相对不受损害。 靶细胞包括白血病细胞，含病毒细胞，含寄生虫细胞，以及细菌，寄生虫和游离病毒等微生物。