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21.发明申请Novel diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use 有权新型二苯基氮杂环丁酮，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US20050267038A1
公开(公告)日：2005-12-01
申请号：US11155109
申请日：2005-06-17
申请人： Heiner Glombik , Werner Krame , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schafer
发明人： Heiner Glombik , Werner Krame , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schafer
IPC分类号： A61K31/397 , A61K45/00 , A61P1/16 , A61P3/06 , A61P3/10 , A61P5/50 , A61P9/10 , A61P39/06 , A61P43/00 , C07D205/08 , A61K38/08 , A61K38/06 , A61K38/05 , A61K38/04 , A61K31/7052 , C07K7/06 , C07K5/04 , C07K5/06
CPC分类号： C07D205/08 , C07F7/1804
摘要： Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
摘要翻译： 其中R1，R2，R3，R4，R5和R6具有说明书中给出的含义的式I化合物及其生理上可接受的盐。 该化合物适合用作例如降血脂药。
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22.发明申请Novel diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use 有权新型二苯基氮杂环丁酮，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US20080281092A1
公开(公告)日：2008-11-13
申请号：US12219196
申请日：2008-07-17
申请人： Heiner Glombik , Werner Krame , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schafer
发明人： Heiner Glombik , Werner Krame , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schafer
IPC分类号： C07D205/04
CPC分类号： C07D205/08 , C07F7/1804
摘要： Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
摘要翻译： 其中R 1，R 2，R 3，R 4，R 5和R 6具有说明书中给出的含义的式I化合物及其生理上可接受的盐。 该化合物适合用作例如降血脂药。
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23.发明授权公开(公告)号：US07576200B2
公开(公告)日：2009-08-18
申请号：US12219196
申请日：2008-07-17
申请人： Heiner Glombik , Werner Krame , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schäfer
发明人： Heiner Glombik , Werner Krame , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schäfer
IPC分类号： C07D205/08 , C07D263/20 , A61K31/397 , A61K31/70 , C07H17/02
CPC分类号： C07D205/08 , C07F7/1804
摘要： Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
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24.发明申请Novel diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use 有权新型二苯基氮杂环丁酮，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US20070208179A1
公开(公告)日：2007-09-06
申请号：US11797720
申请日：2007-05-07
申请人： Heiner Glombik , Werner Krame , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schafer
发明人： Heiner Glombik , Werner Krame , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schafer
IPC分类号： C07D263/20 , C07D205/08
CPC分类号： C07D205/08 , C07F7/1804
摘要： Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
摘要翻译： 其中R1，R2，R3，R4，R5和R6具有说明书中给出的含义的式I化合物及其生理上可接受的盐。 该化合物适合用作例如降血脂药。
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25.发明授权公开(公告)号：US06992067B2
公开(公告)日：2006-01-31
申请号：US10021502
申请日：2001-12-19
申请人： Heiner Glombik , Werner Krame , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schäfer
发明人： Heiner Glombik , Werner Krame , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schäfer
IPC分类号： A61K31/70 , A61K31/397 , C07H17/02
CPC分类号： C07D205/08 , C07F7/1804
摘要： Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
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26.发明申请NOVEL DIPHENYLAZETIDINONE SUBSTITUTED BY PIPERAZINE-1-SULFONIC ACID AND HAVING IMPROVED PHARMACOLOGICAL PROPERTIES 审中-公开由哌嗪-1-磺酸取代的新型二氢吡啶酮，具有改善的药理性质公开(公告)号：US20090264402A1
公开(公告)日：2009-10-22
申请号：US12432997
申请日：2009-04-30
申请人： Gerhard Jaehne , Wendelin Frick , Andreas Lindenschmidt , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Claus-Dieter Graf , Wolfgang Schmider
发明人： Gerhard Jaehne , Wendelin Frick , Andreas Lindenschmidt , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Claus-Dieter Graf , Wolfgang Schmider
IPC分类号： A61K31/496 , C07D403/12 , A61P3/06 , C07D413/12
CPC分类号： C07D295/205 , C07D205/08 , C07D263/22
摘要： The invention therefore relates to the compound of the formula I or a pharmaceutically acceptable salt thereof, its pharmaceutically composition and uses.
摘要翻译： 因此，本发明涉及式I化合物或其药学上可接受的盐，其药物组合物和用途。
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27.发明授权1,4-benzothiepine 1,1-dioxide derivatives substituted by benzyl radicals, method for their preparation, pharmaceuticals comprising these compounds, and the use thereof 有权被苄基取代的1,4-苯并噻吩1,1-二氧化物衍生物，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US07956085B2
公开(公告)日：2011-06-07
申请号：US12465911
申请日：2009-05-14
申请人： Wendelin Frick , Heiner Glombik , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
发明人： Wendelin Frick , Heiner Glombik , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
IPC分类号： A61K31/38 , C07D409/08
CPC分类号： C07H5/06 , A61K31/38 , A61K31/7028 , A61K45/06 , C07D409/12 , C07H5/04 , C07H7/02 , C07H7/027 , C07H13/12 , C07H15/26 , A61K2300/00
摘要： This invention relates to Novel 1,4-benzothiepine 1,1-dioxide derivatives substituted by benzyl radicals, method for their preparation, pharmaceuticals comprising these compounds, and the use thereof.
摘要翻译： 本发明涉及由苄基取代的新型1,4-苯并噻吩1,1-二氧化物衍生物，其制备方法，包含这些化合物的药物及其用途。
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28.发明授权1,4-benzothiepin-1,1-dioxide derivatives which are substituted with fluorine, method for producing the same, drugs containing said compounds and use thereof 有权被氟取代的1,4-苯并硫代-1,1-二氧化物衍生物，其制备方法，含有所述化合物的药物及其用途公开(公告)号：US08101583B2
公开(公告)日：2012-01-24
申请号：US12465928
申请日：2009-05-14
申请人： Heiner Glombik , Wendelin Frick , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
发明人： Heiner Glombik , Wendelin Frick , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
IPC分类号： C07D281/10 , A61K31/55 , A61K31/70
CPC分类号： C07H7/02 , A61K31/38 , A61K31/7028 , A61K45/06 , C07D409/12 , C07H5/04 , C07H5/06 , C07H7/027 , C07H13/12 , C07H15/26 , A61K2300/00
摘要： This invention relates to Novel 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with fluorine, method for producing the same, drugs containing said compounds and use thereof.
摘要翻译： 本发明涉及被氟取代的新的1,4-苯并硫代-1,1-二氧化物衍生物，其制备方法，含有所述化合物的药物及其用途。
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29.发明授权1,4-benzothiepin-1,1-dioxide derivatives which are substituted with cyclohexyl groups, method for producing the same, drugs containing said compounds and use thereof 有权被环己基取代的1,4-苯并噻吩-1-,1-二氧化物衍生物，其制备方法，含有所述化合物的药物及其用途公开(公告)号：US07923468B2
公开(公告)日：2011-04-12
申请号：US12465920
申请日：2009-05-14
申请人： Wendelin Frick , Heiner Glombik , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
发明人： Wendelin Frick , Heiner Glombik , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
IPC分类号： A61K31/38 , C07D337/08
CPC分类号： C07D337/08
摘要： This invention relates to Novel 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with cyclohexyl groups, method for producing the same, drugs containing said compounds and use thereof.
摘要翻译： 本发明涉及用环己基取代的新的1,4-苯并硫苯-1,1-二氧化物衍生物，其制备方法，含有所述化合物的药物及其用途。
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30.发明申请NOVEL 1,4-BENZOTHIEPIN-1, 1-DIOXIDE DERIVATIVES WITH IMPROVED PROPERTIES METHOD FOR PRODUCING THE SAME, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF 有权具有改进性质的新颖的1,4-苯并二氢吡喃-1,1-二氧化物衍生物，其制备方法，含有化合物的药物及其用途公开(公告)号：US20100035834A1
公开(公告)日：2010-02-11
申请号：US12465883
申请日：2009-05-14
申请人： Heiner Glombik , Wendelin Frick , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
发明人： Heiner Glombik , Wendelin Frick , Stefan Theis , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer
CPC分类号： C07H5/06 , C07D409/12
摘要： This invention relates to Novel 1,4-benzothiepin-1,1-dioxide derivatives with improved properties, method for producing the same, drugs containing said compounds and use thereof.
摘要翻译： 本发明涉及具有改进性质的新型1,4-苯并硫代-1,1-二氧化物衍生物，其制备方法，含有所述化合物的药物及其用途。
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