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21.
公开(公告)号:US10954485B1
公开(公告)日:2021-03-23
申请号:US17101897
申请日:2020-11-23
Applicant: Inscripta, Inc.
Inventor: Phillip Belgrader , Don Masquelier , Andrew Garst , Richard Fox
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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22.
公开(公告)号:US20200346168A1
公开(公告)日:2020-11-05
申请号:US16928312
申请日:2020-07-14
Applicant: Inscripta, Inc.
Inventor: Phillip Belgrader , Don Masquelier , Matthew Estes , Bruce Chabansky , Andrew Garst , Richard Fox , Jorge Bernate
IPC: B01D63/08
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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23.
公开(公告)号:US10760043B2
公开(公告)日:2020-09-01
申请号:US16823269
申请日:2020-03-18
Applicant: Inscripta, Inc.
Inventor: Andrew Garst , Richard Fox , Phillip Belgrader , Don Masquelier
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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24.
公开(公告)号:US20200216794A1
公开(公告)日:2020-07-09
申请号:US16820292
申请日:2020-03-16
Applicant: Inscripta, Inc.
Inventor: Phillip Belgrader , Don Masquelier , Andrew Garst , Richard Fox
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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25.
公开(公告)号:US20200095533A1
公开(公告)日:2020-03-26
申请号:US16597831
申请日:2019-10-09
Applicant: Inscripta, Inc.
Inventor: Andrew Garst , Richard Fox , Phillip Belgrader , Don Masquelier
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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26.
公开(公告)号:US10533152B1
公开(公告)日:2020-01-14
申请号:US16399988
申请日:2019-04-30
Applicant: Inscripta, Inc.
Inventor: Phillip Belgrader , Don Masquelier , Bruce Chabansky , Jorge Bernate , Andrew Garst , Richard Fox
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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公开(公告)号:US11236441B2
公开(公告)日:2022-02-01
申请号:US17377272
申请日:2021-07-15
Applicant: Inscripta, Inc.
Inventor: Richard Fox , Daniel Held
IPC: C12N9/22 , C40B50/06 , C40B30/04 , C40B40/10 , C07K16/28 , C07K14/74 , C40B70/00 , C12N15/81 , C12N15/85 , C12N15/90 , C40B20/04 , C40B40/02 , C12N15/10
Abstract: The present disclosure provides shuttle vectors for editing exogenous polynucleotides in heterologous live cells, as well as automated methods, modules, and multi-module cell editing instruments and systems for performing the editing methods.
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公开(公告)号:US20220002907A1
公开(公告)日:2022-01-06
申请号:US17377272
申请日:2021-07-15
Applicant: Inscripta, Inc.
Inventor: Richard Fox , Daniel Held
IPC: C40B50/06 , C12N9/22 , C40B30/04 , C40B40/10 , C07K16/28 , C07K14/74 , C40B70/00 , C12N15/81 , C12N15/85 , C12N15/90 , C40B20/04 , C40B40/02 , C12N15/10
Abstract: The present disclosure provides shuttle vectors for editing exogenous polynucleotides in heterologous live cells, as well as automated methods, modules, and multi-module cell editing instruments and systems for performing the editing methods.
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29.
公开(公告)号:US20210163877A1
公开(公告)日:2021-06-03
申请号:US17175612
申请日:2021-02-13
Applicant: Inscripta, Inc.
Inventor: Phillip Belgrader , Don Masquelier , Andrew Garst , Richard Fox
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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30.
公开(公告)号:US20210108171A1
公开(公告)日:2021-04-15
申请号:US17102414
申请日:2020-11-23
Applicant: Inscripta, Inc.
Inventor: Andrew Garst , Richard Fox , Phillip Belgrader , Don Masquelier
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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