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公开(公告)号：US06361933B1
公开(公告)日：2002-03-26
申请号：US09512139
申请日：2000-02-23
IPC分类号： A01N100
CPC分类号： A01N1/02 , A01N1/0221 , A01N1/0226 , C12N1/04 , Y10T436/108331
摘要： The present invention provides solutions and methods for preserving living biological materials that enable organs, tissues and cells to be stored for extended periods of time with minimal loss of biological activity. The inventive solutions are substantially isotonic with the biological material to be preserved and are substantially free of dihydrogen phosphate, bicarbonate, nitrate, bisulfate and iodide. In one embodiment, preferred for the preservation of platelets, the solutions comprise betaine, sodium chloride and sodium citrate. For the preservation of many living biological materials, the inventive solutions preferably contain a calcium salt selected from the group consisting of calcium sulfate and calcium chloride.
摘要翻译： 本发明提供了用于保存活体生物材料的方法和方法，其使器官，组织和细胞能够以最小的生物活性损失被长时间储存。 本发明溶液与待保存的生物材料基本上是等渗的，并且基本上不含磷酸二氢盐，碳酸氢盐，硝酸盐，硫酸氢盐和碘化物。 在一个实施方案中，优选用于保存血小板，溶液包括甜菜碱，氯化钠和柠檬酸钠。 为了保存许多活的生物材料，本发明的溶液优选含有选自硫酸钙和氯化钙的钙盐。
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公开(公告)号：US5912168A
公开(公告)日：1999-06-15
申请号：US713557
申请日：1996-08-30
申请人： James D. Watson , Fritz Rudert
发明人： James D. Watson , Fritz Rudert
IPC分类号： C12N15/09 , A61K38/00 , A61K48/00 , A61P9/10 , A61P25/28 , C07K14/47 , C07K14/705 , C12N15/85 , C12N15/63 , C12N15/11 , C12N15/12
CPC分类号： C07K14/4747 , C07K14/70578 , C12N15/85 , C12N2830/008 , C12N2830/85
摘要： Regulatory DNA sequences that silence and enhance transcription of coding portions of the CD95 gene, which is instrumental in apoptosis, are disclosed. Proteinaceous transcription factors that bind to the silencer and enhancer regulatory sequences are also disclosed and are useful for modulating the expression of CD95 or other proteins. Methods for regulating apoptosis have therapeutic and prophylactic applications for a variety of disorders, including cancer, viral and retroviral infections, neurodegenerative disorders, immune system dysfunction, and other disorders.
摘要翻译： 公开了调节DNA序列，其沉默并增强编码部分CD95基因的转录，其在凋亡中起作用。 还公开了结合消音器和增强子调节序列的蛋白质转录因子，并且可用于调节CD95或其他蛋白质的表达。 用于调节凋亡的方法具有治疗和预防性应用，用于各种疾病，包括癌症，病毒和逆转录病毒感染，神经变性疾病，免疫系统功能障碍和其它疾病。
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公开(公告)号：USH1147H
公开(公告)日：1993-03-02
申请号：US635258
申请日：1990-12-28
申请人： Kevin J. Kennelley , Eugene R. Thomas , Robert J. Voorhees , James D. Watson , Daniel S. Sullivan
发明人： Kevin J. Kennelley , Eugene R. Thomas , Robert J. Voorhees , James D. Watson , Daniel S. Sullivan
IPC分类号： C09K8/54
CPC分类号： C09K8/54
摘要： A method for treating a hydrocarbon stream containing free sulfur wherein a formulation comprising a diaryldisulfide and a film forming corrosion inhibitor are introduced into the hydrocarbon stream.
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公开(公告)号：US08355892B2
公开(公告)日：2013-01-15
申请号：US12303299
申请日：2007-06-06
CPC分类号： G05B23/0256
摘要： A method and apparatus for diagnosing causes of a malfunction of an electronic whiteboard that includes a white-board surface, the method comprising the steps of linking a remote computer that includes a remote display to the electronic whiteboard from a remote location, interacting with the whiteboard surface to generate X and Y coordinates associated with surface activity, transmitting at least one of the X and Y coordinates associated with the surface activity to the remote computer, displaying at least a subset of the at least one of X and Y coordinates via the remote display and examining the at least a subset of the at least one of X and Y coordinates via the remote display to ascertain the cause of a board malfunction.
摘要翻译： 一种用于诊断包括白板表面的电子白板故障原因的方法和装置，所述方法包括以下步骤：将远程显示器的远程计算机从远程位置与电子白板连接，与白板交互 表面以产生与表面活动相关联的X和Y坐标，将与表面活动相关联的X和Y坐标中的至少一个传送到远程计算机，经由远程显示X和Y坐标中的至少一个坐标的至少一个子集 经由远程显示器显示和检查X和Y坐标中的至少一个的至少一个子集，以确定电路板故障的原因。
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25.发明授权Methods for isolating and harvesting lignin and isolated lignin preparations produced using the methods 失效使用该方法分离和收获木质素和分离的木质素制剂的方法公开(公告)号：US08053566B2
公开(公告)日：2011-11-08
申请号：US12203057
申请日：2008-09-02
CPC分类号： C07G1/00 , D21C3/20 , D21C5/00 , D21C11/0007
摘要： Lignin polymers having distinctive properties, including a generally high molecular weight and generally homogeneous size distribution, as well as preservation of native reactive side groups, are isolated by solvent extraction of plant materials. Methods for isolation of lignin polymers, and for use of the isolated lignin polymers are disclosed. Compositions containing lignin isolated from plant materials, such as carbon fiber composites, resins, adhesive binders and coatings, polyurethane-based foams, rubbers and elastomers, plastics, films, paints, nutritional supplements, food and beverage additives are disclosed. Xylose and xylose derivatives, furfural, fermentable sugars, cellulose and hemi-cellulose products may be used directly or further processed. The lignin polymers and other plant-derived products disclosed herein may be produced in abundance at low cost, and may be used as substitutes for feedstocks originating from fossil fuel or petrochemical sources in the manufacture of various products.
摘要翻译： 通过植物材料的溶剂萃取分离具有特征性质的木质素聚合物，包括通常高分子量和通常均匀的粒度分布，以及天然活性侧基的保存。 公开了分离木质素聚合物的方法和用于分离的木质素聚合物的方法。 公开了包含从植物材料分离的木质素的组合物，例如碳纤维复合材料，树脂，粘合剂粘合剂和涂层，聚氨酯基泡沫，橡胶和弹性体，塑料，薄膜，油漆，营养补充剂，食品和饮料添加剂。 木糖和木糖衍生物，糠醛，可发酵糖，纤维素和半纤维素产品可直接使用或进一步加工。 本文公开的木质素聚合物和其它植物衍生产品可以以低成本丰富地生产，并且可以用作来自化石燃料或石油化学源的原料的替代品，用于制造各种产品。
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公开(公告)号：US07649086B2
公开(公告)日：2010-01-19
申请号：US11745993
申请日：2007-05-08
CPC分类号： D21C5/00 , D21C3/20 , D21C11/0007 , Y02E50/16 , Y02E50/17
摘要： An integrated process for the production of ethanol from woody plant material is provided, the process comprising: contacting a continuous flow of the plant material with a counter-current continuous flow of an aqueous ethanol solution at elevated temperature and pressure to provide plant material depleted of lignin; removing ethanol from the lignin-depleted plant material; contacting a continuous flow of the lignin-depleted plant material with water at elevated temperature and pressure to solubilize xylose within the plant material; and hydrolyzing cellulose present in the plant material to form glucose, which in turn is fermented to produce ethanol.
摘要翻译： 提供了用于从木质植物材料生产乙醇的综合方法，该方法包括：在高温和高压下使植物材料的连续流与逆流的乙醇水溶液连续流动接触，以提供耗尽的植物材料 木质素 从木质素贫乏的植物材料中除去乙醇; 使木质素贫乏的植物材料的连续流动在升高的温度和压力下与水接触以在植物材料中溶解木糖; 并水解存在于植物材料中的纤维素以形成葡萄糖，其又被发酵以产生乙醇。
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27.发明授权Polynucleotides, polypeptides expressed by the polynucleotides and methods for their use 失效多核苷酸，多核苷酸表达的多肽及其使用方法公开(公告)号：US06380362B1
公开(公告)日：2002-04-30
申请号：US09724864
申请日：2000-11-28
申请人： James D. Watson , James G. Murison
发明人： James D. Watson , James G. Murison
IPC分类号： C07K1400
摘要： Novel polynucleotides including partial and extended sequences, and open reading frames, are provided, together with probes and primers, DNA constructs comprising the polynucleotides, biological materials and organisms incorporating the polynucleotides, polypeptides expressed by the polynucleotides, and methods for using the polynucleotides and polypeptides.
摘要翻译： 提供包括部分和延伸的序列以及开放阅读框的新型多核苷酸以及探针和引物，包含多核苷酸的DNA构建体，结合多核苷酸的生物材料和生物体，由多核苷酸表达的多肽，以及使用多核苷酸和多肽的方法 。
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公开(公告)号：US5853619A
公开(公告)日：1998-12-29
申请号：US755309
申请日：1996-11-22
摘要： A low toxic corrosion inhibitor comprises (A) mercaptocarboxylic acid having from 2 to 6 carbon atoms, and (B) a polyamine/fatty acid/carboxylic acid adduct. The preferred combination of (A) and (B) includes mercaptoacetic acid and ethylenetetramine/tall oil acd/acrylic acid adduct.
摘要翻译： 低毒性缓蚀剂包括（A）具有2-6个碳原子的巯基羧酸，和（B）多胺/脂肪酸/羧酸加合物。 （A）和（B）的优选组合包括巯基乙酸和亚乙基四胺/妥尔油酸/丙烯酸加合物。
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公开(公告)号：US4008164A
公开(公告)日：1977-02-15
申请号：US453215
申请日：1974-03-21
申请人： James D. Watson , James R. Stanford
发明人： James D. Watson , James R. Stanford
CPC分类号： C02F5/10 , Y10S159/13 , Y10S507/927 , Y10S507/936
摘要： Copolymers of acrylic acid and methyl acrylate are prepared which are stable against precipitation in waters containing calcium even at a pH of 10 and at elevated temperatures and are especially useful in inhibiting the deposition of calcium from waters containing calcium, in underground formations, in cooling waters and other processes where it is desirable to prevent calcium deposits on metal surfaces or other surfaces in contact with water containing calcium.
摘要翻译： 制备丙烯酸和丙烯酸甲酯的共聚物，其即使在pH为10且在升高的温度下也能稳定地存在含钙的水中，并且特别可用于抑制在地下地层中的含钙水沉积在冷却水中 以及期望防止金属表面或与含钙的水接触的其它表面上的钙沉积的其它方法。
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公开(公告)号：US08890842B2
公开(公告)日：2014-11-18
申请号：US12174398
申请日：2008-07-16
CPC分类号： G06F3/0428 , G06F3/0304
摘要： An eraser is usable in a display system having a display surface. The eraser includes one or more optical detection elements for determining the coordinates of the eraser relative to the display surface.
摘要翻译： 橡皮擦可用于具有显示面的显示系统。 橡皮擦包括用于确定擦除器相对于显示表面的坐标的一个或多个光学检测元件。
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