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    Drug-eluting stent cover and method of use
    21.
    发明申请
    Drug-eluting stent cover and method of use 有权
    药物洗脱支架盖及使用方法

    公开(公告)号：US20060271165A1

    公开(公告)日：2006-11-30

    申请号：US11497652

    申请日：2006-08-01

    Applicant: Philip Yip ,  James Jacobs ,  Syed Hossainy ,  Jon Becker ,  Timothy Limon

    Inventor： Philip Yip ,  James Jacobs ,  Syed Hossainy ,  Jon Becker ,  Timothy Limon

    IPC: A61F2/90

    CPC classification number: A61F2/91 ,  A61F2/90 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2250/0036 ,  A61F2250/0067 ,  A61F2250/0071 ,  Y10S623/903

    Abstract: An intravascular stent includes an eluting sheath fabricated from a mesh for controlled release of therapeutic drugs and for delivery of the therapeutic drugs in localized drug therapy in a blood vessel. The eluting sheath is attached to at least a portion of an outside surface area of the stent structure and is fabricated from a mesh designed to neck down in response to a radially outward directed force resulting in the uniform expansion of the stent. The eluting sheath can be loaded with at least one therapeutic drug for the release thereof at a treatment site to facilitate repair of a damaged vessel. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.

    Abstract translation: 血管内支架包括由用于控制释放治疗药物的网格和用于在血管中局部药物治疗中递送治疗药物的筛网制成的洗脱鞘。 洗脱鞘附着到支架结构的外表面区域的至少一部分上，并且由设计成颈部向下的网眼制成，以响应径向向外的力而导致支架的均匀膨胀。 洗脱鞘可以装载至少一种用于在治疗部位释放的治疗药物，以便于修复受损血管。 支架在纵向具有高度的柔性，但具有足够的容器壁覆盖和径向强度足以保持打开动脉或其他体腔。

    METHOD FOR ASSESSING STENOSIS SEVERITY THROUGH STENOSIS MAPPING
    25.
    发明申请
    METHOD FOR ASSESSING STENOSIS SEVERITY THROUGH STENOSIS MAPPING 审中-公开
    通过STENOSIS MAPPING评估STENOSIS严重程度的方法

    公开(公告)号：US20160000397A1

    公开(公告)日：2016-01-07

    申请号：US14643024

    申请日：2015-03-10

    Applicant: Zhongle Wu ,  James Jacobs

    Inventor： Zhongle Wu ,  James Jacobs

    IPC: A61B6/00 ,  A61B5/026 ,  A61B8/08 ,  A61B6/03

    CPC classification number: A61B6/5217 ,  A61B5/0044 ,  A61B5/02007 ,  A61B5/02035 ,  A61B5/021 ,  A61B5/0263 ,  A61B5/1075 ,  A61B5/7282 ,  A61B6/032 ,  A61B6/504 ,  A61B6/5205 ,  A61B8/0891

    Abstract: A method of assessing stenosis severity for a patient includes obtaining patient information relevant to assessing severity of a stenosis, including anatomical imaging data of the patient. Based on the anatomical imaging data, the existence of any lesions of concerns may be identified. A three dimensional image can be generated of any irregular shaped lesion of concern and a surrounding area from the patient anatomical imaging data. A plurality of comparative two dimensional lesion specific models may be created that have conditions that correspond to the three dimensional model. The comparative two dimensional models may represent vessels having regular shaped lesions with each of the comparative two dimensional models represents a different stenosis severity. The three dimensional model can then be mapped to one of the plurality of comparative two dimensional models. After this mapping, a diagnosis of whether the patient has coronary artery disease may be made.

    Abstract translation: 评估患者狭窄严重程度的方法包括获得与评估狭窄程度相关的患者信息，包括患者的解剖成像数据。 基于解剖成像数据，可以确定任何病症的存在。 可以从患者的解剖学成像数据中产生所关注的任何不规则形状的病变和周围区域的三维图像。 可以创建具有对应于三维模型的条件的多个对比二维损伤特定模型。 比较二维模型可以代表具有规则形状损伤的血管，每个比较二维模型代表不同的狭窄严重程度。 然后可以将三维模型映射到多个比较二维模型中的一个。 在该映射之后，可以对患者是否患有冠状动脉疾病进行诊断。

    GUIDEWIRE HAVING LINEAR CHANGE IN STIFFNESS
    26.
    发明申请
    GUIDEWIRE HAVING LINEAR CHANGE IN STIFFNESS 有权
    具有线性变化的GUIDEWIRE

    公开(公告)号：US20110230840A1

    公开(公告)日：2011-09-22

    申请号：US13150973

    申请日：2011-06-01

    Applicant: Wayne E. Cornish ,  John Schreiner ,  James Jacobs ,  Marc M. Jalisi ,  Mark T. Richardson ,  Kent C. Stalker ,  Olin J. Palmer

    Inventor： Wayne E. Cornish ,  John Schreiner ,  James Jacobs ,  Marc M. Jalisi ,  Mark T. Richardson ,  Kent C. Stalker ,  Olin J. Palmer

    IPC: A61M25/09

    CPC classification number: A61B5/6851 ,  A61M25/09 ,  A61M2025/09083 ,  A61M2025/09175

    Abstract: The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.

    Abstract translation: 本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。 本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度线性变化 的设备。 该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该轮廓优选被配置成在装置的纵向部分上产生芯的刚度的线性变化。

    Methods for manufacturing a coated stent-balloon assembly
    27.
    发明授权
    Methods for manufacturing a coated stent-balloon assembly 失效
    涂覆的支架 - 球囊组件的制造方法

    公开(公告)号：US07648727B2

    公开(公告)日：2010-01-19

    申请号：US10928587

    申请日：2004-08-26

    Applicant: Syed F. A. Hossainy ,  Srinivasan Sridharan ,  James Jacobs

    Inventor： Syed F. A. Hossainy ,  Srinivasan Sridharan ,  James Jacobs

    IPC: A61L33/00

    CPC classification number: A61L31/08 ,  A61F2/958 ,  A61F2002/9522 ,  A61M25/1027 ,  A61M2025/1031 ,  Y10S606/908

    Abstract: Methods of coating a stent subsequent to mounting or crimping of the stent on a balloon of a catheter assembly are disclosed. One method includes forming a sacrificial layer on a balloon of a catheter assembly; followed by mounting a stent on the balloon, the stent including struts separated by gaps; followed by forming a stent coating on the stent; and followed by removal of the sacrificial layer. Another method includes mounting a stent on a balloon, the stent including struts separated by gaps; followed by forming a sacrificial layer on the balloon in the areas of the gaps between struts of the stent; followed by forming a coating on the stent; and followed by removing the sacrificial layer, wherein the coating remains on an outer surface of the stent.

    Abstract translation: 公开了在将支架安装或压接在导管组件的球囊上之后涂覆支架的方法。 一种方法包括在导管组件的球囊上形成牺牲层; 随后将支架安装在气囊上，支架包括由间隙分开的支柱; 然后在支架上形成支架涂层; 然后除去牺牲层。 另一种方法包括将支架安装在气囊上，支架包括由间隙分开的支柱; 然后在支架的支柱之间的间隙的区域中在气囊上形成牺牲层; 然后在支架上形成涂层; 然后除去牺牲层，其中涂层保留在支架的外表面上。

    Battery controller and method for controlling a battery
    29.
    发明申请
    Battery controller and method for controlling a battery 有权
    电池控制器和控制电池的方法

    公开(公告)号：US20050194937A1

    公开(公告)日：2005-09-08

    申请号：US10793951

    申请日：2004-03-08

    Applicant: James Jacobs

    Inventor： James Jacobs

    IPC: H02J7/00 ,  H02J9/00 ,  H02M1/00

    CPC classification number: H02J7/0018 ,  Y02T10/7055 ,  Y10T307/707

    Abstract: A battery controller for charging and discharging a plurality of batteries is disclosed. The battery controller has a plurality of direct current to direct current (DC to DC) converters connected to each other in series. Each battery of a plurality of batteries is electrically connectable to a respective DC to DC converter. A co-ordinator connected to each of the plurality of DC to DC converters controls charging and discharging of the battery electrically connected to the respective converter. The co-ordinator can also control charging and discharging of any one of the batteries to ensure that the battery retains sufficient electrical capacity, and, to increase the longevity of the respective batteries. Because each battery is electrically connected to a respective DC to DC converter, the energy from one battery can be used to charge another battery in order to monitor battery characteristics including energy capacity of each battery. Each of the DC to DC converters is selected to operate preferably below 30 volts while the total voltage of the entire battery system can be much more than 30 volts depending on the number of DC to DC converters placed in series.

    Abstract translation: 公开了一种用于对多个电池进行充电和放电的电池控制器。 电池控制器具有多个直流到串联连接的直流（DC-DC）转换器。 多个电池的每个电池可电连接到相应的DC-DC转换器。 连接到多个DC到DC转换器中的每一个的协调器控制电连接到各个转换器的电池的充电和放电。 协调器还可以控制任何一个电池的充电和放电，以确保电池保持足够的电容，并且增加各个电池的寿命。 因为每个电池电连接到相应的DC到DC转换器，所以可以使用来自一个电池的能量来对另一个电池充电，以便监视包括每个电池的能量容量的电池特性。 每个DC-DC转换器被选择为优选地低于30伏特，而整个电池系统的总电压可以大大超过30伏，这取决于串联放置的DC-DC转换器的数量。

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