Abstract:
An electromechanical coin sound simulator in a gaming machine having a controller, is disclosed. The generated coin sound may be used as a sound effect during game play or may be used to audibly signify a coin award associated with a winning game outcome. The electromechanical coin sound simulator includes a motor coupled to the controller, and an arm assembly activated for rotative movement by the motor. The arm assembly includes portions adapted to strike an interior area of the gaming machine to generate the coin sound. The arm assembly may be a multilink arm assembly, a single link arm assembly, or a spring loaded arm assembly. The electromechanical coin sound simulator may also be configured with a solenoid assembly, belt-feeding coin conveyor assembly, or a disc-feeding coin conveyor assembly, to name a few.
Abstract:
A gaming machine includes a coin input device for receiving coins that can be used to play a wagering game. The coin input device includes a coin control mechanism and a coin validation component downstream from the coin control mechanism. The coin control mechanism slows the velocity and properly spaces the coins to prevent jamming and to allow the coin validation component to accurately identify the currency value and authenticity of each coin.
Abstract:
Recombinant active glucocerebrosidase is produced by a eukaryotic cell. Also, a cell includes nucleic acid encoding enzymatically active glucocerebrosidase; also a eukaryotic organism contains such a cell. Also, a method for producing enzymatically active glucocerebrosidase includes steps of introducing glucocerebrosidase-encoding nucleic acid into a eukaryotic cell, causing the cell to express glucocerebrosidase, and purifying the glucocerebrosidase from the cell.
Abstract:
The invention relates to novel methods and kits for treating or preventing disease through the administration of random copolymers. The invention also relates to the treatment of autoimmune diseases, such as multiple sclerosis, and to the administration of random copolymers in treatment regimen comprising formulations that are administered at intervals greater than 24 hours, or to sustained release formulations which administer the copolymer over a period greater than 24 hours. The invention further relates to methods for conducting a pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the formulations or dosing regimens of random copolymer described herein.
Abstract:
The invention relates to novel methods and kits for treating or preventing disease through the administration of random copolymers comprising amino acids tyrosine (Y), phenylalanine (F), alanine (A), and lysine (K). The invention also relates to the treatment of autoimmune diseases, such as multiple sclerosis, and to the administration of random copolymers in treatment regimen comprising formulations that are administered at intervals greater than 24 hours, or to sustained release formulations which administer the copolymer over a period greater than 24 hours. The invention further relates to methods for conducting a pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the formulations or dosing regimens of random copolymer described herein.
Abstract:
The present invention provides methods and compositions for treating autoimmune diseases and other unwanted immune reactions comprising administering a copolymer that binds to one or more HLA-DQ molecules and modulates DQ-restricted T cell responses. The copolymers are random copolymers of amino acids and copolymers comprising anchor residues to facilitate binding to the DQ binding pockets.
Abstract:
A slot machine comprises a housing, a plurality of physical symbol-bearing reels mounted in the housing, and a display arrangement positioned in front of the reels and interchangeable in the same housing between at least two of the following: (i) a display panel without an interior cavity, (ii) a light-guiding panel having an illuminated interior, and (iii) a transmissive video display.
Abstract:
The invention relates to novel methods and kits for treating or preventing disease through the administration of random copolymers. The invention also relates to the treatment of autoimmune diseases, such as multiple sclerosis, and to the administration of random copolymers in treatment regimen comprising formulations that are administered at intervals greater than 24 hours, or to sustained release formulations which administer the copolymer over a period greater than 24 hours. The invention further relates to methods for conducting a pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the formulations or dosing regimens of random copolymer described herein.
Abstract:
The invention relates to novel methods and kits for treating or preventing disease through the administration of random copolymers. The invention also relates to the treatment of autoimmune diseases, such as multiple sclerosis, and to the administration of random copolymers in treatment regimen comprising formulations that are administered at intervals greater than 24 hours, or to sustained release formulations which administer the copolymer over a period greater than 24 hours. The invention further relates to methods for conducting a pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the formulations or dosing regimens of random copolymer described herein.
Abstract:
According to one aspect of the invention, a gaming machine for conducting a wagering game, comprising a physically configurable button panel and at least one mechanical button removably disposed in the button panel. The gaming machine also comprises an input panel disposed adjacent to the button to produce an output signal in response to a predetermined movement of the button and a controller for initiating a function in response to the output signal.