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公开(公告)号：US20110200537A1
公开(公告)日：2011-08-18
申请号：US13092292
申请日：2011-04-22
CPC分类号： A61K31/165 , A61K9/2072 , A61K9/2886
摘要： The present invention relates to a coated dosage form having openings to expose the core material or an intermediate coating layer. The invention also relates to methods for manufacturing such coated dosage forms.
摘要翻译： 本发明涉及具有露出核心材料或中间涂层的开口的涂覆剂型。 本发明还涉及制备这种包衣剂型的方法。
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公开(公告)号：US07101573B2
公开(公告)日：2006-09-05
申请号：US09966441
申请日：2001-09-28
摘要： The present invention provides a composition for forming a compressed solid dosage form that is a free-flowing compressible admixture of simethicone, an adsorbant, and an optional active agent, wherein the weight ratio of simethicone to adsorbent is at least 1:2.22. Also included are solid dosage forms made from a free-flowing compressible admixture of simethicone, an adsorbant, and an optional active agent, wherein the weight ratio of simethicone to adsorbent is at least 1:2.22.
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公开(公告)号：US20100135982A1
公开(公告)日：2010-06-03
申请号：US12699129
申请日：2010-02-03
IPC分类号： A61K38/47 , A61K31/695 , A61K33/24 , A61P1/00
摘要： The present invention provides a composition for forming a compressed solid dosage form that is a free-flowing compressible admixture of simethicone, an adsorbant, and an optional active agent, wherein the weight ratio of simethicone to adsorbent is at least 1:2.22. Also included are solid dosage forms made from a free-flowing compressible admixture of simethicone, an adsorbant, and an optional active agent, wherein the weight ratio of simethicone to adsorbent is at least 1:2.22.
摘要翻译： 本发明提供一种用于形成压缩固体剂型的组合物，其是可与二甲基硅油，吸附剂和任选活性剂的自由流动的可压缩混合物，其中二甲硅油与吸附剂的重量比至少为1:2.22。 还包括由二甲硅油，吸附剂和任选的活性剂的自由流动的可压缩混合物制备的固体剂型，其中二甲硅油与吸附剂的重量比至少为1:2.22。
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公开(公告)号：US07691409B2
公开(公告)日：2010-04-06
申请号：US11460741
申请日：2006-07-28
IPC分类号： A61K31/12 , A61K33/12 , A61K31/15 , A61K31/165 , A61K31/445
摘要： The present invention provides a composition for forming a compressed solid dosage form that is a free-flowing compressible admixture of simethicone, an adsorbant, and an optional active agent, wherein the weight ratio of simethicone to adsorbent is at least 1:2.22. Also included are solid dosage forms made from a free-flowing compressible admixture of simethicone, an adsorbant, and an optional active agent, wherein the weight ratio of simethicone to adsorbent is at least 1:2.22.
摘要翻译： 本发明提供一种用于形成压缩固体剂型的组合物，其是可与二甲基硅油，吸附剂和任选活性剂的自由流动的可压缩混合物，其中二甲硅油与吸附剂的重量比至少为1:2.22。 还包括由二甲硅油，吸附剂和任选的活性剂的自由流动的可压缩混合物制备的固体剂型，其中二甲硅油与吸附剂的重量比至少为1:2.22。
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公开(公告)号：US20100034894A1
公开(公告)日：2010-02-11
申请号：US12537333
申请日：2009-08-07
IPC分类号： A61K9/16 , A61K47/36 , A61K31/138
CPC分类号： A61K9/1623 , A61K9/5026 , A61K9/5042 , A61K9/5073 , A61K31/00 , A61K31/135 , A61K31/137 , A61K31/138 , A61K31/451 , A61K31/495
摘要： A method of making a granulation comprising the steps of (a) combining sucralose, a polar solvent, a wettable material and an active agent, thereby forming a mixture; and (b) drying the mixture, thereby forming the granulation.
摘要翻译： 制造造粒的方法包括以下步骤：（a）将三氯蔗糖，极性溶剂，可湿性物质和活性剂混合，从而形成混合物; 和（b）干燥混合物，从而形成造粒物。
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