Granulates of hexahydropyrazine derivatives which can be administered orally
    22.
    发明授权
    Granulates of hexahydropyrazine derivatives which can be administered orally 有权
    可以口服给药的六氢吡嗪衍生物颗粒

    公开(公告)号:US06503536B2

    公开(公告)日:2003-01-07

    申请号:US09214858

    申请日:1999-01-13

    IPC分类号: A61K914

    摘要: The present invention relates to the preparation of orally administrable granules of hexahydropyrazine derivatives by mixing the active compound in the presence of suitable solvents with hydrophobic carriers, if appropriate in the presence of auxiliaries, and converting the resulting mixture, if appropriate, into other ready-to-use forms.

    摘要翻译: 本发明涉及通过在合适的溶剂存在下将活性化合物与疏水载体混合来制备六氢吡嗪衍生物的口服给药颗粒,如果合适的话,在助剂的存在下,将所得混合物转化成其它即用型 使用形式。

    Biological material embedded in hydrogels, a process for the embedding
thereof, and its use as artificial seed
    23.
    发明授权
    Biological material embedded in hydrogels, a process for the embedding thereof, and its use as artificial seed 失效
    嵌入水凝胶中的生物材料,其嵌入方法及其作为人造种子的用途

    公开(公告)号:US6164012A

    公开(公告)日:2000-12-26

    申请号:US230379

    申请日:1999-04-27

    CPC分类号: C05G3/0047 A01H4/001 A01N3/00

    摘要: The invention relates to a completely biodegradable hydrogel comprising polyester polyurethane polyurea containing urea groups as well as polysaccharides and/or their derivatives, the hydrogel containing plant material capable of dividing. The invention also relates to a process for the embedding of the biological material and the fabrication and shaping of the hydrogels from aqueous solutions. The hydrogels according to the invention may be used as coating material for embedding biological material capable of dividing, especially plant material, preferably plant cells, protoplasts, plant tissues and plant organs, as well as zygotic or somatic plant embryos, under sterile conditions for the purpose of protecting the material during storage, transport and handling. The hydrogels according to the invention may also contain further additives, for example, plant protection agents or nutrients. The embedded biological plant material according to the invention may be used as artificial seed.

    摘要翻译: PCT No.PCT / EP97 / 03906 Sec。 一九九九年四月二十七日 102(e)1999年4月27日PCT 1997年7月21日PCT公布。 公开号WO98 / 05197 日期1998年2月12日本发明涉及包含含有尿素基团的聚酯聚氨酯聚脲以及多糖和/或其衍生物的完全可生物降解的水凝胶,所述水凝胶含有能够分裂的植物材料。 本发明还涉及用于从水溶液中包埋生物材料和水凝胶的制造和成型的方法。 根据本发明的水凝胶可以用作在无菌条件下包埋能够分裂的生物材料的涂层材料,特别是植物材料,优选植物细胞,原生质体,植物组织和植物器官以及合子或体细胞植物胚胎 在储存,运输和处理过程中保护材料的目的。 根据本发明的水凝胶还可以含有其它添加剂,例如植物保护剂或营养物质。 根据本发明的嵌入式生物植物材料可以用作人造种子。