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21.发明申请MR-Compatible Blood Sampling System For PET Imaging Applications in Combined PET/MR Imaging System 有权MR兼容血液采样系统用于PET / MR成像系统的PET成像应用公开(公告)号：US20090108206A1
公开(公告)日：2009-04-30
申请号：US12260966
申请日：2008-10-29
CPC分类号： G01R33/28 , A61B5/150992 , G01R33/481 , G01T1/1603
摘要： An automated blood sampling system for PET imaging applications that can be operated in or very near to the field of view (FOV) of an MR scanner, such as in a combined MR/PET imaging system. A radiation detector uses APDs (avalanche photo-diodes) to collect scintillation light from crystals in which the positron-electron annihilation photons are absorbed. The necessary gamma shielding is made from a suitable shielding material, preferably tungsten polymer composite. Because the APDs are quite small and are magnetically insensitive, they can be operated in the strong magnetic field of an MR apparatus without disturbance.
摘要翻译： 用于PET成像应用的自动采血系统，其可以在MR扫描器的视野（FOV）中或非常接近的范围内操作，例如在组合的MR / PET成像系统中。 辐射检测器使用APD（雪崩光电二极管）从正电子 - 电子湮灭光子被吸收的晶体中收集闪烁光。 必要的伽马屏蔽由合适的屏蔽材料制成，优选钨聚合物复合材料。 由于APD相当小并且磁性不敏感，所以它们可以在无扰动的MR设备的强磁场中操作。
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22.发明申请Positron Emission Tomography Detector Based on Monolithic Scintillator Crystal 有权基于单片闪烁晶体的正电子发射断层扫描检测器公开(公告)号：US20130009067A1
公开(公告)日：2013-01-10
申请号：US13540674
申请日：2012-07-03
CPC分类号： G01T1/1642 , A61B6/037 , G01T1/1644 , G01T1/2985
摘要： A high-resolution nuclear imaging detector for use in systems such as positron emission tomography includes a monolithic scintillator crystal block in combination with a single photomultiplier tube read-out channel for timing and total energy signals, and one or more solid-state photosensor pixels arrays on one or more vertical surfaces of the scintillator block to determine event position information.
摘要翻译： 用于诸如正电子发射断层摄影系统的高分辨率核成像检测器包括与用于定时和总能量信号的单个光电倍增管读出通道组合的单片闪烁体晶体块和一个或多个固态光电传感器像素阵列 在闪烁体块的一个或多个垂直表面上，以确定事件位置信息。
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23.发明申请System and Method for Providing Depth of Interaction Detection Using Positron Emission Tomography 有权使用正电子发射断层扫描提供相互作用检测深度的系统和方法公开(公告)号：US20110192982A1
公开(公告)日：2011-08-11
申请号：US13017617
申请日：2011-01-31
CPC分类号： G01T1/2985 , A61B6/037 , G01T1/1644 , G01T1/2002 , G01T1/2008
摘要： A system and method is provided for determining depth of interaction (DOI) information. The system and method includes a detector configured to generate DOI information as a result of radiation emitted from a radiation source. The system and method further includes a plurality of scintillator pixels forming a block, wherein the plurality of scintillator pixels have a first portion and a second portion. A first medium distributed in an alternating pattern of coupling and separation between each of the scintillator pixels in a first portion or second portion of the block is also provided. A plurality of sensors for detecting scintillation events across the plurality of scintillators based on the alternating pattern of coupling and separation between each of the scintillator pixels, wherein DOI information is provided by a position profile of the block, and an image processor for generating a 3 dimensional image from the DOI information are also included.
摘要翻译： 提供了用于确定交互深度（DOI）信息的系统和方法。 该系统和方法包括检测器，被配置为产生作为辐射源发射的辐射的结果的DOI信息。 该系统和方法还包括形成块的多个闪烁体像素，其中多个闪烁体像素具有第一部分和第二部分。 还提供了分布在块的第一部分或第二部分中的每个闪烁体像素之间的耦合和分离的交替模式的第一介质。 多个传感器，用于基于每个闪烁体像素之间的耦合和分离的交替模式来检测跨多个闪烁体的闪烁事件，其中DOI信息由块的位置分布提供，以及用于产生3的闪烁体的图像处理器 还包括来自DOI信息的三维图像。
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公开(公告)号：US20110074426A1
公开(公告)日：2011-03-31
申请号：US12585867
申请日：2009-09-28
申请人： Matthias J. Schmand , Markus Vester , Nan Zhang
发明人： Matthias J. Schmand , Markus Vester , Nan Zhang
CPC分类号： A61B6/4411 , A61B5/0035 , A61B5/055 , A61B6/037 , A61B6/4417 , G01R33/481 , G01T1/1603 , G01T1/1644
摘要： An emission tomography detector module and an emission tomography scanner are disclosed. In at least one embodiment, the emission tomography detector modules includes a scintillator to capture an photon, the scintillator emitting a scintillating light on capturing the photon; a first type of solid-state photodetector to detect the scintillating light; and a second type of solid-state photodetector to detect the scintillating light, wherein the first type of solid-state photodetector and the second type of solid-state photodetector are different with respect to a detecting property.
摘要翻译： 公开了一种发射断层摄影检测器模块和发射断层扫描仪。 在至少一个实施例中，发射断层摄影检测器模块包括闪光体以捕获光子，闪烁体在捕获光子时发射闪烁光; 用于检测闪烁光的第一种类型的固态光电检测器; 以及用于检测闪烁光的第二类型的固态光电检测器，其中所述第一类型的固态光电检测器和所述第二类型的固态光电检测器相对于检测特性是不同的。
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25.发明申请公开(公告)号：US20100066426A1
公开(公告)日：2010-03-18
申请号：US12558007
申请日：2009-09-11
申请人： Matthias J. Schmand , Nan Zhang
发明人： Matthias J. Schmand , Nan Zhang
IPC分类号： H03L5/00
CPC分类号： G01T1/248
摘要： A simple, low cost circuit with only passive components, and thus low power consumption, is provided for baseline restoration of an AC coupled signal. The circuit includes a passive network of diodes arranged in a star configuration and an RF-transformer. A differential signal strategy may be employed by including a differential amplifier at the input and output of the passive network.
摘要翻译： 提供了一种简单的低成本电路，仅具有无源组件，因此具有低功耗，用于AC耦合信号的基线恢复。 该电路包括以星形结构布置的二极管的无源网络和RF变压器。 可以通过在无源网络的输入和输出处包括差分放大器来采用差分信号策略。
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26.发明申请Concurrent DC-Coupled Anode and Dynode Readout Scheme For PET Block Detectors 有权用于PET块检测器的并行DC耦合阳极和Dynode读出方案公开(公告)号：US20080290282A1
公开(公告)日：2008-11-27
申请号：US11753067
申请日：2007-05-24
IPC分类号： G01T1/20
CPC分类号： G01T1/1642 , G01T1/208
摘要： A scintillation detector including one or more photomultiplier tubes, a scintillation block optically attached to the photomultiplier tubes, and a DC-coupled bleeder circuit combining outputs of dynodes of the photomultipliers to provide a DC-coupled dynode output together with a DC-coupled anode output of the photomultiplier tubes. The DC-coupled bleeder circuit includes a RF transformer. A positive high voltage supply also can be used together with a DC-coupled bleeder circuit for the anode outputs.
摘要翻译： 闪烁检测器，包括一个或多个光电倍增管，与光电倍增管光学连接的闪烁块，以及组合光电倍增管的倍增电极输出的DC耦合泄放电路，以提供DC耦合的倍增电极输出以及直流耦合的阳极输出 的光电倍增管。 直流耦合放电电路包括RF变压器。 阳极高压电源也可以与阳极输出的直流耦合泄放电路一起使用。
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27.发明授权公开(公告)号：US07408164B2
公开(公告)日：2008-08-05
申请号：US10441682
申请日：2003-05-20
IPC分类号： G01T1/20
CPC分类号： G01T1/2002 , G01T1/202
摘要： A detector array including a plurality of scintillators for use in association with an imaging device. The detector array is provided for accurate determination of the location of the impingement of radiation upon an individual scintillator detector. An air gap is disposed between the scintillator elements, thereby increasing the packing fraction and overall sensitivity of the array. The amount of light transmitted down the scintillator element and the amount of light transmitted to adjacent elements is modified to optimize the identification of each element in a position profile map by adjusting the surface finish of the detector elements.
摘要翻译： 一种检测器阵列，包括用于与成像装置相关联的多个闪烁体。 检测器阵列被提供用于准确地确定辐射冲击位置在单独的闪烁体检测器上。 在闪烁器元件之间设置气隙，从而增加阵列的封装分数和整体灵敏度。 通过调整检测器元件的表面光洁度来修改向下闪烁体元件传输的光量和透射到相邻元件的光量，以优化位置分布图中每个元素的识别。
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公开(公告)号：US07019297B2
公开(公告)日：2006-03-28
申请号：US10441681
申请日：2003-05-20
IPC分类号： G01T1/202
CPC分类号： G01T1/202 , B33Y70/00 , B33Y80/00 , G01T1/2002
摘要： A method for fabricating an array adapted to receive a plurality of scintillators for use in association with an imaging device. The method allows the creation of a detector array such that location of the impingement of radiation upon an individual scintillator detector is accurately determinable. The array incorporates an air gap between all the scintillator elements. Certain scintillators may have varying height reflective light partitions to control the amount of light sharing which occurs between elements. Light transmission is additionally optimized by varying the optical transmission properties of the reflective light partition, such as by varying the thickness and optical density of the light partitions. In certain locations, no light partitions exist, thereby defining an air gap between those elements. The air gap allows a large increase in the packing fraction and therefore the overall sensitivity of the array.
摘要翻译： 一种用于制造适于接收与成像装置相关联使用的多个闪烁体的阵列的方法。 该方法允许创建检测器阵列，使得能够精确地确定单个闪烁体检测器上的辐射冲击位置。 该阵列包括所有闪烁体元件之间的气隙。 某些闪烁体可以具有变化的高度反射光分区，以控制在元件之间发生的光共享的量。 通过改变反射光分区的光传输特性，例如通过改变光分区的厚度和光密度来另外优化透光。 在某些位置，不存在光分区，从而在这些元件之间限定气隙。 空气间隙允许包装分数大幅度增加，因此阵列的整体灵敏度增加。
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29.发明授权Positron emission tomography detector based on monolithic scintillator crystal 有权基于单片闪烁体晶体的正电子发射断层扫描检测器公开(公告)号：US09194959B2
公开(公告)日：2015-11-24
申请号：US13540674
申请日：2012-07-03
CPC分类号： G01T1/1642 , A61B6/037 , G01T1/1644 , G01T1/2985
摘要： A high-resolution nuclear imaging detector for use in systems such as positron emission tomography includes a monolithic scintillator crystal block in combination with a single photomultiplier tube read-out channel for timing and total energy signals, and one or more solid-state photosensor pixels arrays on one or more vertical surfaces of the scintillator block to determine event position information.
摘要翻译： 用于诸如正电子发射断层摄影系统的高分辨率核成像检测器包括与用于定时和总能量信号的单个光电倍增管读出通道组合的单片闪烁体晶体块和一个或多个固态光电传感器像素阵列 在闪烁体块的一个或多个垂直表面上，以确定事件位置信息。
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公开(公告)号：US09006664B2
公开(公告)日：2015-04-14
申请号：US13115220
申请日：2011-05-25
申请人： Nan Zhang , Niraj K. Doshi , Matthias J. Schmand
发明人： Nan Zhang , Niraj K. Doshi , Matthias J. Schmand
IPC分类号： G01T1/20
CPC分类号： G01T1/2018
摘要： Signals generated by radiation sensors can be encoded to reduce the number of cables needed to transport information from a nuclear imaging apparatus to a processor for reconstruction. For example, signals from 16 radiation sensors can be encoded into three signals: T (top), L (left), and E (energy). This method of encoding signals can be capable of substantially reducing the number of signals, thereby reducing costs. In addition, reducing the number of signals could improve system timing performance by eliminating cable time-skew and facilitate the filter design by downgrading the circuit accuracy requirements such as group-delay error and filter signal skews.
摘要翻译： 可以编码由辐射传感器产生的信号以减少将信息从核成像设备传输到处理器以进行重建所需的电缆数量。 例如，来自16个辐射传感器的信号可以被编码成三个信号：T（上），L（左）和E（能量）。 这种编码信号的方法能够显着减少信号的数量，从而降低成本。 此外，减少信号数量可以通过消除电缆时间偏移来提高系统定时性能，并通过降低电路精度要求（如组延迟误差和滤波器信号偏移）来促进滤波器设计。
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