公开(公告)号：US08974524B2

公开(公告)日：2015-03-10

申请号：US14056467

申请日：2013-10-17

Applicant: Medtronic, Inc.

Inventor： Hubert Yeung ,  John Shanahan ,  Joshua Dwork ,  Adam Shipley ,  Jeffrey Allen ,  Susheel Deshmukh ,  Kishore Udipi ,  Ya Guo

IPC: A61F2/24 ,  A61F2/966 ,  A61F2/95

CPC classification number: A61F2/2436 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/966 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2220/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008

Abstract: A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer.

Abstract translation: 一种经皮支架置入的瓣膜输送装置，包括内轴，护套和输送胶囊。 护套可滑动地容纳内轴。 胶囊近端区域附接到护套。 胶囊远端区域被配置为在正常和扩张状态之间转变。 远端区域的直径在扩张状态下较大，并且胶囊包括自然地呈现正常状态的形状记忆组件。 该装置可操作以执行可逆部分展开过程，其中假体的一部分暴露在胶囊的远端并允许径向扩张。 随后，随着胶囊的远端前进，远侧区域转变到扩张状态并且将塌陷力施加到假体上，导致假体径向折叠并在输送胶囊内重新捕获。 胶囊可以包括由聚合物包封的激光切割管。

公开(公告)号：US20140236287A1

公开(公告)日：2014-08-21

申请号：US13772676

申请日：2013-02-21

Applicant: MEDTRONIC, INC.

Inventor： Cynthia Clague ,  Scott Mosher ,  Marian Creaven ,  Declan Costello ,  Gavin Kenny ,  Michael Krivoruchko ,  Adam Shipley ,  Mark Torrianni ,  Kshitija Garde ,  Eric Richardson

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2250/0003 ,  A61F2250/0039 ,  A61F2250/0069 ,  A61F2310/00023

Abstract: A method of preventing paravalvular leakage includes concurrent delivery of a heart valve prosthesis and an annular sealing component. During delivery, the sealing component is moved from a first position to a second position of the heart valve prosthesis which is longitudinally spaced apart from the first position of the heart valve prosthesis. The sealing component is secured around the heart valve prosthesis at the second position by a contoured outer surface of the heart valve prosthesis. The sealing component may be a flexible ring or may be a cylindrical flexible sleeve having a plurality of ribs longitudinally extending over the cylindrical sleeve. The ribs operate to deploy the sealing component such that at least a portion of the cylindrical sleeve buckles outwardly away from the outer surface of the heart valve prosthesis.

Abstract translation: 防止瓣膜间泄漏的方法包括同时传送心脏瓣膜假体和环形密封部件。 在输送期间，密封部件从心脏瓣膜假体的第一位置移动到与心脏瓣膜假体的第一位置纵向间隔开的第二位置。 密封部件通过心脏瓣膜假体的轮廓外表面在第二位置处固定在心脏瓣膜假体周围。 密封部件可以是柔性环，或者可以是具有在圆柱形套筒上纵向延伸的多个肋的圆柱形柔性套管。 肋条用于展开密封部件，使得圆柱形套筒的至少一部分向外离开远离心脏瓣膜假体的外表面。

公开(公告)号：US20140172075A1

公开(公告)日：2014-06-19

申请号：US14095465

申请日：2013-12-03

Applicant: Medtronic, Inc.

Inventor： Robert J. Murray, III ,  Charles Tabor ,  Andrew Crisman ,  Adam Shipley

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2230/0054

Abstract: A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached includes a shaft assembly including a distal end, an intermediate portion, and a first coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve via a first tether. A sheath assembly defines a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The first coupling structure is configured to be manipulated in a first direction to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve.

Abstract translation: 一种与具有附接有阀结构的支架框架的假体心脏瓣膜一起使用的输送系统包括：轴组件，包括远端，中间部分和设置在远端附近的第一联接结构， 经由第一系绳的假体心脏瓣膜的远端。 护套组件限定尺寸为可滑动地容纳轴组件的内腔。 输送系统被配置成从其中护套组件包围假体心脏瓣膜的负载状态转变到其中护套组件从假体心脏瓣膜抽出的展开状态。 第一联接结构构造成在第一方向上被操纵以提供假体心脏瓣膜的远端的可控膨胀或收缩。

公开(公告)号：US20140046435A1

公开(公告)日：2014-02-13

申请号：US14056467

申请日：2013-10-17

Applicant: Medtronic, Inc.

Inventor： Hubert Yeung ,  John Shanahan ,  Joshua Dwork ,  Adam Shipley ,  Jeffrey Allen ,  Susheel Deshmukh ,  Kishore Udipi ,  Ya Guo

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/966 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2220/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008

Abstract: A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer.

Abstract translation: 一种经皮支架置入的瓣膜输送装置，包括内轴，护套和输送胶囊。 护套可滑动地容纳内轴。 胶囊近端区域附接到护套。 胶囊远端区域被配置为在正常和扩张状态之间转变。 远端区域的直径在扩张状态下较大，并且胶囊包括自然地呈现正常状态的形状记忆组件。 该装置可操作以执行可逆部分展开过程，其中假体的一部分暴露在胶囊的远端并允许径向扩张。 随后，随着胶囊的远端前进，远侧区域转变到扩张状态并且将塌陷力施加到假体上，导致假体径向折叠并在输送胶囊内重新捕获。 胶囊可以包括由聚合物包封的激光切割管。