Antisense modulation of damage-specific DNA binding protein 1, p127 expression
    21.
    发明授权
    Antisense modulation of damage-specific DNA binding protein 1, p127 expression 失效
    反义调制损伤特异性DNA结合蛋白1,p127表达

    公开(公告)号:US06855700B2

    公开(公告)日:2005-02-15

    申请号:US09731457

    申请日:2000-12-06

    摘要: Antisense compounds, compositions and methods are provided for modulating the expression of Damage-specific DNA binding protein 1, p127. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Damage-specific DNA binding protein 1, p127. Methods of using these compounds for modulation of Damage-specific DNA binding protein 1, p127 expression and for treatment of diseases associated with expression of Damage-specific DNA binding protein 1, p127 are provided.

    摘要翻译: 提供反义化合物,组合物和方法用于调节损伤特异性DNA结合蛋白1,p127的表达。 组合物包含靶向编码损伤特异性DNA结合蛋白1,p127的核酸的反义化合物,特别是反义寡核苷酸。 提供了使用这些化合物调节损伤特异性DNA结合蛋白1,p127表达和治疗与损伤特异性DNA结合蛋白1,p127表达相关疾病的方法。

    Antisense modulation of protein phosphatase 2 catalytic subunit beta expression
    22.
    发明授权
    Antisense modulation of protein phosphatase 2 catalytic subunit beta expression 有权
    蛋白磷酸酶2催化亚基β表达的反义调制

    公开(公告)号:US06602713B1

    公开(公告)日:2003-08-05

    申请号:US09780045

    申请日:2001-02-09

    申请人: Jacqueline Wyatt

    发明人: Jacqueline Wyatt

    IPC分类号: C12N1586

    摘要: Antisense compounds, compositions and methods are provided for modulating the expression of Protein Phosphatase 2 catalytic subunit beta. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Protein Phosphatase 2 catalytic subunit beta. Methods of using these compounds for modulation of Protein Phosphatase 2 catalytic subunit beta expression and for treatment of diseases associated with expression of Protein Phosphatase 2 catalytic subunit beta are provided.

    摘要翻译: 提供反义化合物,组合物和方法用于调节蛋白磷酸酶2催化亚基β的表达。 组合物包含靶向编码蛋白磷酸酶2催化亚单位β的核酸的反义化合物,特别是反义寡核苷酸。 提供了使用这些化合物调节蛋白磷酸酶2催化亚单位β表达和治疗与蛋白磷酸酶2催化亚基β的表达相关的疾病的方法。

    Antisense modulation of phosphorylase kinase Alpha 2 expression
    24.
    发明授权
    Antisense modulation of phosphorylase kinase Alpha 2 expression 有权
    磷酸酶激酶Alpha 2表达的反义调节

    公开(公告)号:US06458591B1

    公开(公告)日:2002-10-01

    申请号:US09657453

    申请日:2000-09-07

    申请人: Jacqueline Wyatt

    发明人: Jacqueline Wyatt

    IPC分类号: C12Q168

    摘要: Antisense compounds, compositions and methods are provided for modulating the expression of Phosphorylase kinase alpha 2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Phosphorylase kinase alpha 2. Methods of using these compounds for modulation of Phosphorylase kinase alpha 2 expression and for treatment of diseases associated with expression of Phosphorylase kinase alpha 2 are provided.

    摘要翻译: 提供反义化合物,组合物和方法用于调节磷酸化酶激酶α2的表达。组合物包含靶向编码磷酸化酶激酶α的核酸的反义化合物,特别是反义寡核苷酸。使用这些化合物调节磷酸化酶激酶α2的方法 提供了表达和用于治疗与磷酸化酶激酶α2的表达相关的疾病。

    Antisense modulation of SR-CYP expression
    26.
    发明授权
    Antisense modulation of SR-CYP expression 失效
    SR-CYP表达的反义调制

    公开(公告)号:US06475797B1

    公开(公告)日:2002-11-05

    申请号:US09706197

    申请日:2000-11-03

    申请人: Jacqueline Wyatt

    发明人: Jacqueline Wyatt

    IPC分类号: C12N1563

    摘要: Antisense compounds, compositions and methods are provided for modulating the expression of SR-cyp. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding SR-cyp. Methods of using these compounds for modulation of SR-cyp expression and for treatment of diseases associated with expression of SR-cyp are provided.

    摘要翻译: 提供反义化合物,组合物和方法用于调节SR-cyp的表达。 组合物包含靶向编码SR-cyp的核酸的反义化合物,特别是反义寡核苷酸。 提供了使用这些化合物调节SR-cyp表达和治疗与SR-cyp1表达相关的疾病的方法。

    Antisense modulation of protein phosphatase 2 catalytic subunit alpha expression
    27.
    发明授权
    Antisense modulation of protein phosphatase 2 catalytic subunit alpha expression 有权
    蛋白磷酸酶2催化亚基α表达的反义调制

    公开(公告)号:US06465250B1

    公开(公告)日:2002-10-15

    申请号:US09780049

    申请日:2001-02-09

    申请人: Jacqueline Wyatt

    发明人: Jacqueline Wyatt

    IPC分类号: C12Q168

    摘要: Antisense compounds, compositions and methods are provided for modulating the expression of Protein Phosphatase 2 catalytic subunit alpha. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Protein Phosphatase 2 catalytic subunit alpha. Methods of using these compounds for modulation of Protein Phosphatase 2 catalytic subunit alpha expression and for treatment of diseases associated with expression of Protein Phosphatase 2 catalytic subunit alpha are provided.

    摘要翻译: 提供反义化合物,组合物和方法用于调节蛋白磷酸酶2催化亚基α的表达。 组合物包含靶向编码蛋白磷酸酶2催化亚基α的核酸的反义化合物,特别是反义寡核苷酸。 提供了使用这些化合物调节蛋白磷酸酶2催化亚基α表达和治疗与蛋白磷酸酶2催化亚基α表达相关疾病的方法。

    Antisense modulation of damage-specific DNA binding protein 2, p48 expression
    29.
    发明授权
    Antisense modulation of damage-specific DNA binding protein 2, p48 expression 有权
    损伤特异性DNA结合蛋白2,p48表达的反义调制

    公开(公告)号:US06379960B1

    公开(公告)日:2002-04-30

    申请号:US09732199

    申请日:2000-12-06

    IPC分类号: C12Q168

    摘要: Antisense compounds, compositions and methods are provided for modulating the expression of Damage-specific DNA binding protein 2, p48. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Damage-specific DNA binding protein 2, p48. Methods of using these compounds for modulation of Damage-specific DNA binding protein 2, p48 expression and for treatment of diseases associated with expression of Damage-specific DNA binding protein 2, p48 are provided.

    摘要翻译: 提供反义化合物,组合物和方法用于调节损伤特异性DNA结合蛋白2,p48的表达。 组合物包含靶向编码损伤特异性DNA结合蛋白2,p48的核酸的反义化合物,特别是反义寡核苷酸。 提供了使用这些化合物调节损伤特异性DNA结合蛋白2,p48表达和治疗与损伤特异性DNA结合蛋白2,p48表达有关的疾病的方法。