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公开(公告)号：US07944551B2
公开(公告)日：2011-05-17
申请号：US12249046
申请日：2008-10-10
申请人： Paul Stanley Addison , James Watson
发明人： Paul Stanley Addison , James Watson
IPC分类号： A61B5/1455
CPC分类号： A61B5/726 , A61B5/1455 , A61B5/14551 , A61B5/7225 , A61B5/742 , G06F19/00 , G06T5/10 , G06T2207/20064 , G06T2207/30076 , G16H40/63
摘要： Techniques for the display of a signal with a wavelet transform of that signal in a wavelet transform viewer are disclosed, according to embodiments. According to embodiments, the wavelet transform viewer can display a plot of physiological signals such as a photoplethysmograph (PPG) signal. A portion of the plot of the signal can be selected. A wavelet transform the selected portion of the signal can be calculated and a wavelet plot of the tranformed signal can be displayed simultaneously with that signal. A plot of the selected portion of the signal can also be simultaneously displayed with both the plot of the signal and the wavelet plot.
摘要翻译： 根据实施例公开了用于在小波变换观察器中显示具有该信号的小波变换的信号的技术。 根据实施例，小波变换观察器可以显示诸如光电容积描记器（PPG）信号的生理信号的图。 可以选择信号图的一部分。 可以计算小波变换信号的选定部分，并且可以与该信号同时显示变换信号的小波图。 信号的所选部分的图也可以同时显示信号和小波图的绘图。
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公开(公告)号：US20100016690A1
公开(公告)日：2010-01-21
申请号：US12249068
申请日：2008-10-10
申请人： James Watson , Paul Stanley Addison
发明人： James Watson , Paul Stanley Addison
IPC分类号： A61B5/1455
CPC分类号： A61B5/14551 , A61B5/7203 , A61B5/7257 , A61B5/726 , A61B5/742
摘要： According to embodiments, techniques for using continuous wavelet transforms and spectral transforms to determine oxygen saturation from photoplethysmographic (PPG) signals are disclosed. According to embodiments, a first oxygen saturation may be determined from wavelet transformed PPG signals and a second oxygen saturation may be determined from spectral transformed PPG signals. An optimal oxygen saturation may be determined by selecting one of the first and the second oxygen saturation or by combining the first and the second oxygen saturation. According to embodiments, a spectral transform of PPG signals may be performed to identify a frequency region associated with a pulse rate of the PPG signal. A continuous wavelet transform of the PPG signals at a scale corresponding to the identified frequency region may be performed to determine oxygen saturation from the wavelet transformed signal.
摘要翻译： 根据实施例，公开了使用连续小波变换和频谱变换来确定来自光电体积描记术（PPG）信号的氧饱和度的技术。 根据实施例，可以从小波变换的PPG信号确定第一氧饱和度，并且可以从光谱变换的PPG信号确定第二氧饱和度。 可以通过选择第一和第二氧饱和度之一或通过组合第一和第二氧饱和度来确定最佳氧饱和度。 根据实施例，可以执行PPG信号的频谱变换以识别与PPG信号的脉冲速率相关联的频率区域。 可以执行以与所识别的频率区域对应的比例的PPG信号的连续小波变换，以从小波变换信号确定氧饱和度。
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公开(公告)号：US20090326871A1
公开(公告)日：2009-12-31
申请号：US12245336
申请日：2008-10-03
申请人： James Watson , Paul Stanley Addison
发明人： James Watson , Paul Stanley Addison
IPC分类号： G06F19/00
CPC分类号： A61B5/14551 , A61B5/04012 , A61B5/7207 , A61B5/726 , G06K9/00516
摘要： According to embodiments, a method and system for artifact detection in signals is disclosed. The artifacts may take the form of movement artifacts in physiological (e.g., pulse oximetry) signals. Artifacts in the wavelet space of the physiological signal may be removed, replaced, ignored, filtered, or otherwise modified by determining the energy within a predefined moving area of the wavelet scalogram, comparing the determined energy within the predefined moving area of the wavelet scalogram to a threshold value, and masking at least one area of artifact in the wavelet scalogram based, at least in part, on the comparison. From the enhanced signal, physiological parameters, for example, respiration, respiratory effort, pulse, and oxygen saturation, may be more reliably and accurately derived or computed.
摘要翻译： 根据实施例，公开了一种用于信号中伪影检测的方法和系统。 人造物可以采取生理（例如脉搏血氧测定）信号中的运动假象的形式。 可以通过确定小波图标的预定移动区域内的能量来比较所确定的小波图示图的预定移动区域内的能量，将小波图形的小波空间中的人造物除以，替换，忽略，滤波或以其它方式进行修改， 至少部分地基于该比较来掩蔽小波缩写图中的伪像的至少一个区域。 从增强的信号，可以更可靠和准确地导出或计算生理参数，例如呼吸，呼吸力，脉搏和氧饱和度。
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公开(公告)号：US20090326402A1
公开(公告)日：2009-12-31
申请号：US12245366
申请日：2008-10-03
申请人： Paul Stanley Addison , James Watson
发明人： Paul Stanley Addison , James Watson
IPC分类号： A61B5/08
CPC分类号： A61B5/08 , A61B5/0816 , A61B5/087 , A61B5/14551 , A61B5/726
摘要： According to embodiments, methods and systems for determining effort is disclosed. Effort may relate to a measure of strength of at least one repetitive feature in a signal. Effort may also relate to physical effort or work of a process (e.g., respiratory effort) that may affect the signal (e.g., a PPG signal). Effort may be determined through feature analysis of a transformed signal that has been transformed via a continuous wavelet transform. For example, respiratory effort may be determined using a scalogram generated based at least in part on a wavelet transform of a physiological signal and analyzing features of the scalogram.
摘要翻译： 根据实施例，公开了用于确定努力的方法和系统。 努力可能涉及信号中至少一个重复特征的强度的度量。 努力还可能涉及可能影响信号（例如，PPG信号）的过程的体力或工作（例如呼吸努力）。 可以通过经由连续小波变换变换的变换信号的特征分析来确定努力。 例如，可以使用至少部分地基于生理信号的小波变换产生的标尺来确定呼吸努力并分析标尺的特征。
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25.发明申请公开(公告)号：US20090326388A1
公开(公告)日：2009-12-31
申请号：US12249053
申请日：2008-10-10
申请人： James Watson , Paul Stanley Addison
发明人： James Watson , Paul Stanley Addison
IPC分类号： A61B5/02
CPC分类号： A61B5/14551 , A61B5/412 , A61B5/726
摘要： The present disclosure relates to systems and methods for detecting features of a signal. According to embodiments, by transposing segments of a signal, such as segments representing pulses in a PPG signal, such that they are stacked next to each other, various characteristics about the signal may be discerned such as information about repetitive features of the signal. According to an embodiment, from a PPG signal respiration information may be determined about individual breaths, blood pressure changes may be determined, and information about other physiological parameters affecting the PPG signal may be determined.
摘要翻译： 本公开涉及用于检测信号特征的系统和方法。 根据实施例，通过将表示PPG信号中的脉冲的信号的段转置为彼此堆叠的信号的段，可以辨别关于信号的各种特性，例如关于信号的重复特征的信息。 根据一个实施例，从PPG信号可以确定关于个体呼吸的呼吸信息，可以确定血压变化，并且可以确定影响PPG信号的关于其他生理参数的信息。
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公开(公告)号：US20090326351A1
公开(公告)日：2009-12-31
申请号：US12437311
申请日：2009-05-07
申请人： Paul Stanley Addison , James Watson
发明人： Paul Stanley Addison , James Watson
IPC分类号： A61B5/02 , A61B5/1455
CPC分类号： A61B5/14551 , A61B5/7207 , A61B5/7225 , A61B5/7232 , A61B5/726
摘要： Embodiments may include systems and methods capable of processing an original signal by selecting and mirroring portions of the signal to create a new signal for further analysis. In an embodiment, the signal may be a photoplethysmograph (PPG) signal and the new signal may be further analyzed using continuous wavelet transforms. Any suitable number of reconstructed new signals may be created from the original signal and scalograms may be derived at least in part from the new signals. Ridges may be extracted from the scalograms of the new signals and secondary scalograms may be further derived from the ridges. A sum along amplitudes technique may be applied to a selected scalogram and may be plotted as a function of the scale of the scalogram. Desired information, such as respiration information within the original signal, may be identified from the plot.
摘要翻译： 实施例可以包括能够通过选择和镜像信号的部分来处理原始信号以创建用于进一步分析的新信号的系统和方法。 在一个实施例中，信号可以是光电容积描记器（PPG）信号，并且可以使用连续小波变换进一步分析新信号。 可以从原始信号创建任何合适数量的重构的新信号，并且可以至少部分地从新的信号导出缩略图。 可以从新信号的缩放图中提取脊，并且可以从脊进一步导出二次标尺。 沿着幅度技术的和可以应用于所选择的标尺，并且可以作为缩放图的尺度的函数来绘制。 可以从绘图中识别所需的信息，例如原始信号内的呼吸信息。
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公开(公告)号：US08827917B2
公开(公告)日：2014-09-09
申请号：US12245336
申请日：2008-10-03
申请人： James Watson , Paul Stanley Addison
发明人： James Watson , Paul Stanley Addison
CPC分类号： A61B5/14551 , A61B5/04012 , A61B5/7207 , A61B5/726 , G06K9/00516
摘要： According to embodiments, a method and system for artifact detection in signals is disclosed. The artifacts may take the form of movement artifacts in physiological (e.g., pulse oximetry) signals. Artifacts in the wavelet space of the physiological signal may be removed, replaced, ignored, filtered, or otherwise modified by determining the energy within a predefined moving area of the wavelet scalogram, comparing the determined energy within the predefined moving area of the wavelet scalogram to a threshold value, and masking at least one area of artifact in the wavelet scalogram based, at least in part, on the comparison. From the enhanced signal, physiological parameters, for example, respiration, respiratory effort, pulse, and oxygen saturation, may be more reliably and accurately derived or computed.
摘要翻译： 根据实施例，公开了一种用于信号中伪影检测的方法和系统。 人造物可以采取生理（例如脉搏血氧测定）信号中的运动假象的形式。 可以通过确定小波图标的预定移动区域内的能量来比较所确定的小波图示图的预定移动区域内的能量，将小波图形的小波空间中的人造物除以，替换，忽略，滤波或以其它方式进行修改， 至少部分地基于该比较来掩蔽小波缩写图中的伪像的至少一个区域。 从增强的信号，可以更可靠和准确地导出或计算生理参数，例如呼吸，呼吸力，脉搏和氧饱和度。
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28.发明授权Methods and apparatus for producing and using lightly filtered photoplethysmograph signals 有权用于生产和使用轻度过滤的光体积描记信号的方法和设备公开(公告)号：US08755854B2
公开(公告)日：2014-06-17
申请号：US12533239
申请日：2009-07-31
申请人： Paul Stanley Addison , James Watson
发明人： Paul Stanley Addison , James Watson
IPC分类号： A61B5/1455 , A61B5/145 , A61B5/00
CPC分类号： A61B5/1455 , A61B5/0059 , A61B5/08 , A61B5/14532 , A61B5/14551 , A61B5/14552 , A61B5/7203 , A61B5/7225 , A61B5/726
摘要： One or more physiological conditions of a patient can be observed by obtaining a photoplethysmograph (“PPG”) signal from the patient and by only lightly filtering that signal. The light filtering of the PPG may be such as to only remove (for example) high frequency noise from that signal, while leaving in the signal most or all frequency components that are due to physiological events in the patient. In this way, such physiological events can be observed via a visual display of the lightly filtered PPG signal and/or via other signal processing of the lightly filtered PPG signal to automatically extract certain physiological parameters or characteristics from that signal.
摘要翻译： 可以通过从患者获得光学体积描记术（“PPG”）信号并且仅轻微过滤该信号可以观察患者的一种或多种生理状态。 PPG的光滤波可以仅仅从该信号去除（例如）高频噪声，同时在信号中留下由于患者生理事件引起的大多数或所有频率分量。 以这种方式，可以通过轻度滤过的PPG信号的视觉显示和/或经由轻度过滤的PPG信号的其它信号处理来观察这种生理事件，以自动从该信号中提取某些生理参数或特征。
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29.发明申请公开(公告)号：US20120259235A1
公开(公告)日：2012-10-11
申请号：US13528755
申请日：2012-06-20
申请人： Paul Stanley Addison , James Watson , Rakesh Sethi
发明人： Paul Stanley Addison , James Watson , Rakesh Sethi
CPC分类号： G06F19/345 , A61B5/0205 , A61B5/021 , A61B5/7264 , G06F19/00 , G06F19/3406 , G16H40/63 , G16H50/20
摘要： Systems and methods are provided for monitoring a correlation between heart rate and blood pressure in a patient. When a characteristic of the correlation exceeds a threshold, a patient status indicator signal is sent to a monitoring device. In some embodiments, the patient status indicator signal indicates a particular medical condition or alerts a care provider to a change in status. In some embodiments, the heart rate signal is used to improve a blood pressure estimate generated by a different signal. In some embodiments, the heart rate, blood pressure and correlation signals are used in a predictive mathematical model to estimate patient status or outcome.
摘要翻译： 提供了系统和方法来监测患者心率和血压之间的相关性。 当相关特性超过阈值时，将患者状态指示信号发送到监视装置。 在一些实施例中，患者状态指示符信号指示特定医疗状况或警告护理提供者改变状态。 在一些实施例中，心率信号用于改善由不同信号产生的血压估计。 在一些实施例中，在预测数学模型中使用心率，血压和相关信号来估计患者状态或结果。
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公开(公告)号：US20120123689A1
公开(公告)日：2012-05-17
申请号：US13292524
申请日：2011-11-09
CPC分类号： G06K9/00516 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/14551 , A61B5/7207 , A61B5/7225 , A61B5/7239 , A61B5/726
摘要： The present disclosure is directed towards embodiments of systems and methods for discriminating (e.g., masking out) scale bands that are determined to be not of interest from a scalogram derived from a continuous wavelet transform of a signal. Techniques for determining whether a scale band is not of interest include, for example, determining whether a scale band's amplitude is being modulated by one or more other bands in the scalogram. Another technique involves determining whether a scale band is located between two other bands and has energy less than that of its neighboring bands. Another technique involves determining whether a scale band is located at about half the scale of another, more dominant (i.e., higher energy) band.
摘要翻译： 本公开涉及用于从由信号的连续小波变换导出的标尺来鉴别（例如，屏蔽）被确定为不感兴趣的标度带的系统和方法的实施例。 用于确定缩放带是否不感兴趣的技术包括例如确定缩放带的幅度是否正在由缩放图中的一个或多个其他频带调制。 另一技术涉及确定尺度带是位于两个其他频带之间并且具有小于其相邻频带的能量的能量。 另一技术涉及确定刻度带是否位于另一个（更高的能量）频带的大约一半的尺度。
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