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公开(公告)号:US20090019028A1
公开(公告)日:2009-01-15
申请号:US11775066
申请日:2007-07-09
IPC分类号: G06F17/30
CPC分类号: G06F17/3087 , G06Q30/0261
摘要: A search query may be interpreted as a number of possible interpretations, and each interpretation may be explored before the results of the search are sent to a user. In one embodiment, a device may split the search query into partitions. Each of the partitions may be submitted, as a search query, to search repositories. Confidence scores based on the results returned from the repositories may be used to determine a measure of confidence of the repository in the search query interpretation.
摘要翻译: 搜索查询可以被解释为许多可能的解释,并且可以在将搜索结果发送给用户之前探查每个解释。 在一个实施例中,设备可以将搜索查询拆分成分区。 可以将每个分区作为搜索查询提交到搜索库。 基于从存储库返回的结果的置信度分数可用于确定存储库在搜索查询解释中的置信度度。
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公开(公告)号:US20080045470A1
公开(公告)日:2008-02-21
申请号:US11666519
申请日:2005-10-31
申请人: Alicja Bielawska , Yusuf Hannun , James Norris , Zdzislaw Szulc , Jian-yun Dong , Jacek Bielawski , David Schwartz , David Holman , Ahmed El-Zawahry , John McKillop
发明人: Alicja Bielawska , Yusuf Hannun , James Norris , Zdzislaw Szulc , Jian-yun Dong , Jacek Bielawski , David Schwartz , David Holman , Ahmed El-Zawahry , John McKillop
IPC分类号: A61K31/40 , A61K31/415 , A61K31/44 , A61K31/445 , A61K31/497 , A61K31/535 , A61K31/70 , A61P43/00 , C07D207/00 , C07D211/00 , C07D233/00 , C07D241/04 , C07D265/30
CPC分类号: C07D213/56 , C07C215/18 , C07C215/28 , C07C275/24
摘要: The invention provides the compounds of formula ( ): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, A, X, Y, a, b and n are as defined herein. Also disclosed are methods for making the compounds of formula (I) and their use in treating or preventing diseases associated with cell overproliferation and dysfunctional sphingolipid signal transduction. The invention also encompasses the use of the compounds in combination with an apoptosis-signaling ligand, such as Fas ligand. Preferably, the Fas ligand is administered in the form of a gene therapy agent.
摘要翻译: 本发明提供式(I)化合物及其药学上可接受的盐,其中R 1,R 2,R 3,R 3 > 4,A,X,Y,a,b和n如本文所定义。 还公开了制备式(I)化合物及其用于治疗或预防与细胞过度增生和功能失调的鞘脂信号转导相关的疾病的方法。 本发明还包括与凋亡信号传导配体如Fas配体组合的化合物的用途。 优选地,Fas配体以基因治疗剂的形式施用。
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23.
公开(公告)号:US20070295011A1
公开(公告)日:2007-12-27
申请号:US11719956
申请日:2004-12-01
申请人: Gabriel Suciu , James Norris , Craig Nordeen
发明人: Gabriel Suciu , James Norris , Craig Nordeen
IPC分类号: F02C7/18
CPC分类号: F02C3/073 , F01D5/022 , F01D5/187 , F02K3/068 , F05D2260/205 , Y02T50/676
摘要: A fan-turbine rotor assembly (24) includes a multitude of turbine blades (34) which each define a turbine blade passage which bleed air from a diffuser section (74) to provide for regenerative cooling. Regenerative cooling airflow is communicated from the radial core airflow passage (80) through the diffuser passages (144), through diffuser aspiration passages (146A, 146B) and into the turbine blade passages (150a). The regenerative cooling airflow exits from the turbine blade passage (150a) and transfers received thermal energy into an annular combustor (30). The received thermal energy is recovered at the highest temperature in the cycle.
摘要翻译: 风扇涡轮转子组件(24)包括多个涡轮机叶片(34),每个涡轮机叶片限定一个涡轮机叶片通道,其从扩散器部分(74)排出空气以提供再生冷却。 再生冷却气流通过扩散器抽吸通道(146A,146B)从径向芯气流通道80通过扩散器通道144进入涡轮叶片通道150a。 再生冷却气流从涡轮机叶片通道(150a)流出并将接收到的热能转移到环形燃烧器(30)中。 接收的热能在循环中的最高温度下回收。
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公开(公告)号:US20070192258A1
公开(公告)日:2007-08-16
申请号:US11372809
申请日:2006-03-10
申请人: James Norris , John Winkelman , Kenneth Miller , John Rojas , Alla Tsipenyuk
发明人: James Norris , John Winkelman , Kenneth Miller , John Rojas , Alla Tsipenyuk
IPC分类号: B65B35/00
CPC分类号: G06Q30/02 , G06Q10/04 , G06Q10/06 , G06Q10/06312 , G06Q10/08 , G06Q10/0833 , G06Q20/102 , H04M3/51 , H04M2203/402
摘要: A computer controlled method that enables a mailer to control when recipients will receive mail mailed by the mailer. The method involves receiving a mailing composition, the desired mailing in home delivery date ranges and carrier schedules; utilizing a prediction model built from historical delivery data to predict when the quantities of mail will arrive for the mailing; and using the prediction model to determine preferred induction dates for the mailing.
摘要翻译: 一种计算机控制的方法,使邮件程序能够控制收件人何时接收邮件发送的邮件。 该方法包括接收邮寄作品,在本地传送日期范围和载体日程表中所需的邮寄; 利用从历史交货数据构建的预测模型来预测邮件的数量何时到达邮寄的时间; 并使用预测模型确定邮寄的优选诱导日期。
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公开(公告)号:US20060212326A1
公开(公告)日:2006-09-21
申请号:US11372636
申请日:2006-03-10
申请人: Kenneth Miller , John Winkelman , John Rojas , Alla Tsipenyuk , James Norris
发明人: Kenneth Miller , John Winkelman , John Rojas , Alla Tsipenyuk , James Norris
IPC分类号: G06F9/44
CPC分类号: G06Q30/02 , G06Q10/04 , G06Q10/06 , G06Q10/06312 , G06Q10/08 , G06Q10/0833 , G06Q20/102 , H04M3/51 , H04M2203/402
摘要: A computer method that is used to predict when recipients of mail pieces will contact a call center in response to information contained in the mail pieces. The method involves, utilizing previous mailing campaign data to determine when the mail piece arrives in the home and when a call center is contacted in response to information in the mail piece; and predicting call volumes based initially on previous campaign data and as the mailing campaign progresses updating call center predictions based on current mailing campaign data.
摘要翻译: 一种计算机方法,用于预测邮件的接收者何时将响应于邮件中包含的信息与呼叫中心联系。 该方法涉及利用先前的邮寄活动数据来确定邮件何时到达家庭,何时响应于邮件中的信息联系呼叫中心; 并且基于最初的活动数据预测呼叫量,并且基于当前的邮件活动数据,邮件活动进行更新呼叫中心预测。
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公开(公告)号:US20060130488A1
公开(公告)日:2006-06-22
申请号:US11016454
申请日:2004-12-17
申请人: Gabriel Suciu , James Norris
发明人: Gabriel Suciu , James Norris
IPC分类号: F02C7/00
CPC分类号: F01D5/066 , F05D2260/4031
摘要: A turbine engine has a first disk and a second disk, each extending radially from an inner aperture to an outer periphery. A coupling, transmits a torque and a longitudinal compressive force between the first and second disks. The coupling has first means for transmitting a majority of the torque and second means, radially outboard of the first means, for transmitting a majority of the force.
摘要翻译: 涡轮发动机具有第一盘和第二盘,每个盘从内孔径向延伸到外周。 联接器在第一和第二盘之间传递扭矩和纵向压缩力。 联接器具有用于传送大部分扭矩和第二装置的第一装置,第一装置的径向外侧,用于传递大部分的力。
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公开(公告)号:US20060096293A1
公开(公告)日:2006-05-11
申请号:US10984461
申请日:2004-11-08
申请人: James Norris , Craig Nordeen , Wendell Twelves
发明人: James Norris , Craig Nordeen , Wendell Twelves
IPC分类号: F02C5/00
摘要: A pulsed combustion apparatus includes a conduit having an outer wall and an inner wall. The inner wall has a number of apertures. An interior space is separated from the outer wall by the inner wall. An induction system is positioned to cyclicly admit charges to the interior space. An ignition system is positioned to ignite the charges. Flow directing surfaces are positioned to at least cyclicly direct cooling air through the apertures.
摘要翻译: 脉冲燃烧装置包括具有外壁和内壁的导管。 内壁具有多个孔。 内部空间通过内壁与外壁分离。 感应系统被定位成循环地允许电荷到内部空间。 定位点火系统以点燃电荷。 流动引导表面被定位成至少循环地引导冷却空气通过孔。
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28.
公开(公告)号:US06968373B1
公开(公告)日:2005-11-22
申请号:US10036014
申请日:2001-12-28
申请人: James Norris , John Everson , Daniel G. LaMastres
发明人: James Norris , John Everson , Daniel G. LaMastres
IPC分类号: G06F15/173 , G06F21/00 , G06Q10/00
CPC分类号: G06Q10/087 , G06F21/10 , G06F2221/0737
摘要: A system (10), computer program, and method for automatically and periodically conducting an inventory of one or more network assets (12) or resources, such as, for example, servers, workstations, or firewalls, using an agent (16) running on each asset (12) to perform the inventory and collect inventory data which may thereafter be sent in a secure manner to a designated location where it can be parsed and from which pertinent information can be saved. Thereafter, the stored information may be used, for example, to generate inventory reports for determining network vulnerabilities, checking software licenses, and tracking network assets. In a preferred embodiment, the system (10) broadly comprises one or more separate instances of an inventory agent (16); one or more collection servers (18); a directory server (20); and a reporting server (22). The present invention also makes use of digital certificates for identification, authentication, and, optionally, encryption purposes.
摘要翻译: 一种系统(10),计算机程序和方法,用于使用运行的代理(16)来自动和周期地执行一个或多个网络资产(12)或资源(例如服务器,工作站或防火墙)的清单 在每个资产(12)上执行库存并收集库存数据,其后可以以安全的方式发送到可以解析的指定位置,并从中可以保存相关信息。 此后,可以使用所存储的信息来例如生成用于确定网络漏洞的清单报告,检查软件许可和跟踪网络资产。 在优选实施例中,系统(10)广泛地包括清单代理(16)的一个或多个单独的实例; 一个或多个收集服务器(18); 目录服务器(20); 和报告服务器(22)。 本发明还利用数字证书进行识别,认证和可选地加密的目的。
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公开(公告)号:US20050118719A1
公开(公告)日:2005-06-02
申请号:US10494880
申请日:2002-11-07
申请人: Michael Schmidt , David Schofield , Caroline Westwater , Joseph Dolan , Brian Hoel , Philip Werner , James Norris , Laura Kasman
发明人: Michael Schmidt , David Schofield , Caroline Westwater , Joseph Dolan , Brian Hoel , Philip Werner , James Norris , Laura Kasman
CPC分类号: C12N15/74 , C07K14/005 , C12N15/63 , C12N15/635 , C12N15/73 , C12N2795/10122
摘要: The invention provides methods and materials involved in delivering nucleic acid to cells and regulating expression of nucleic acid in cells.
摘要翻译: 本发明提供了将核酸递送至细胞并调节核酸在细胞中的表达所涉及的方法和材料。
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公开(公告)号:US20050089110A1
公开(公告)日:2005-04-28
申请号:US10694082
申请日:2003-10-28
申请人: James Norris
发明人: James Norris
CPC分类号: H04L27/2017 , H04L27/186
摘要: A method and apparatus for improving the bandwidth efficiency of a constant envelope continuous phase modulation waveform and transmitting data in a bandwidth efficient manner is disclosed. The method and apparatus utilizes a non-constant envelope continuous phase modulation signal which possesses many of the advantages of a multiple modulation index continuous phase modulation signal. One such advantage is the natural trellis structure of a multiple modulation index continuous phase modulation signal. In comparison to a constant envelope continuous phase modulation waveform, the non-constant envelope continuous phase modulation signal possesses a reduced transmit signal spectra and may also be demodulated by a standard maximum likelihood demodulator without any loss of performance.
摘要翻译: 公开了一种用于提高恒包络连续相位调制波形的带宽效率并以带宽有效的方式发送数据的方法和装置。 该方法和装置利用了具有多调制度连续相位调制信号的许多优点的非恒定包络连续相位调制信号。 一个这样的优点是多调制指数连续相位调制信号的自然网格结构。 与恒定包络连续相位调制波形相比,非恒定包络连续相位调制信号具有降低的发射信号频谱,并且还可以由标准最大似然解调器进行解调而没有任何性能损失。
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