专利检索 ap:("THE BROAD INSTITUTE INC." OR "MASSACHUSETTS INSTITUTE OF TECHNOLOGY" OR "PRESIDENT AND FELLOWS OF HARVARD COLLEGE") AND inv:"Fei RAN" 第 3 页

21.

发明申请
ENGINEERING AND OPTIMIZATION OF IMPROVED SYSTEMS, METHODS AND ENZYME COMPOSITIONS FOR SEQUENCE MANIPULATION 有权

公开(公告)号：US20140273234A1

公开(公告)日：2014-09-18

申请号：US14293674

申请日：2014-06-02

申请人： The Board Institute, Inc. , Massachusetts Institute of Technology

发明人： Feng ZHANG , Fei RAN

IPC分类号： C12N15/85 , C12N9/22

CPC分类号： C12N9/22 , A61K48/00 , C12N9/96 , C12N15/1082 , C12N15/63 , C12N15/8213 , C12N15/85 , C12N15/86 , C12N15/907 , C12N2750/14143 , C12N2800/22 , C12N2810/10

摘要： The invention provides for engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are compositions and methods related to components of a CRISPR complex particularly comprising a Cas ortholog enzyme.