公开(公告)号：US4734411A

公开(公告)日：1988-03-29

申请号：US895099

申请日：1986-08-11

申请人： Masayasu Kurono ,  Yasuaki Kondo ,  Takuji Yamaguchi ,  Toshinao Usui ,  Ryoichi Unno ,  Hiromoto Kimura ,  Masato Fukushima ,  Mitsuru Oka ,  Shinichi Ikeda ,  Noboru Kuboyama ,  Takashi Ito ,  Seiji Miyano ,  Kunihiro Sumoto

发明人： Masayasu Kurono ,  Yasuaki Kondo ,  Takuji Yamaguchi ,  Toshinao Usui ,  Ryoichi Unno ,  Hiromoto Kimura ,  Masato Fukushima ,  Mitsuru Oka ,  Shinichi Ikeda ,  Noboru Kuboyama ,  Takashi Ito ,  Seiji Miyano ,  Kunihiro Sumoto

IPC分类号： A61K31/40 ,  A61K31/54 ,  A61P1/04 ,  C07D487/04 ,  C07D519/00 ,  C07F7/08 ,  A61K31/55 ,  C07D521/00

CPC分类号： C07D487/04 ,  C07F7/0814

摘要： Novel pyrrolizidine compounds represented by the formula ##STR1## wherein R is a radical of ##STR2## R.sup.1 is hydrogen, halogen, alkyl group, alkoxy group, alkanoyl group, trifluoromethyl radical, trimethylsilyl radical or ##STR3## R.sup.2 and R.sup.3 are same or different and are hydrogen or alkyl group, respectively, R.sup.4 is hydrogen, halogen, alkyl group or alkoxy group and m is an integer of 0 to 5,salts thereof, a process for the preparation of same as well as a pharmaceutical agent comprising same.

摘要翻译： 由式（I）表示的新型吡咯烷酮化合物，其中R是R 1的基团是氢，卤素，烷基，烷氧基，烷酰基，三氟甲基，三甲基甲硅烷基或者R 2是 相同或不同，分别为氢或烷基，R4为氢，卤素，烷基或烷氧基，m为0-5的整数，其盐，其制备方法以及药剂，其包含 相同。

公开(公告)号：US5984227A

公开(公告)日：1999-11-16

申请号：US252934

申请日：1999-02-19

申请人： Takuji Yamaguchi ,  Masasuke Funase

发明人： Takuji Yamaguchi ,  Masasuke Funase

IPC分类号： G03D15/00 ,  B65H19/12 ,  G03D13/00 ,  G03B23/02

CPC分类号： G03D13/003

摘要： A film-rewinding apparatus to rewind a film from a cartridge into a container which can accommodate the film therein by inserting the film from an opening of the container. The apparatus comprises a cartridge-supporting portion which supports the cartridge; a shielding door driving mechanism for opening and closing the shielding door; a spool-driving mechanism for feeding the film out by driving the spool; a container-supporting portion for supporting the container; an opening and closing driving mechanism for opening and closing the opening; and a film-dismounting mechanism for dismounting the film from the spool. The film-rewinding apparatus can easily perform rewinding by only operating a handle or lever, or by a switching operation, after the cartridge and the intermediate magazine are set and the cover is locked.

摘要翻译： 一种胶片重绕装置，用于将胶片从胶卷盒中倒带到容器中，该容器可以通过从容器的开口插入胶片来容纳胶片。 该装置包括支撑盒的盒支撑部分; 用于打开和关闭屏蔽门的屏蔽门驱动机构; 卷轴驱动机构，用于通过驱动卷轴来输送胶卷; 用于支撑容器的容器支撑部分; 用于打开和关闭开口的打开和关闭驱动机构; 以及用于从卷轴拆卸胶片的胶片拆卸机构。 在盒和中间盒被设置并且盖被锁定之后，通过仅操作手柄或杠杆或通过切换操作，胶卷重绕装置可以容易地进行倒带。

公开(公告)号：US5929084A

公开(公告)日：1999-07-27

申请号：US860524

申请日：1997-06-27

申请人： Dayuan Zhu ,  Xican Tang ,  Jinlai Lin ,  Cheng Zhu ,  Jingkang Shen ,  Guansong Wu ,  Shanhao Jiang ,  Takuji Yamaguchi ,  Kazuhiro Tanaka ,  Takeshi Wakamatsu ,  Hiroaki Nishimura

发明人： Dayuan Zhu ,  Xican Tang ,  Jinlai Lin ,  Cheng Zhu ,  Jingkang Shen ,  Guansong Wu ,  Shanhao Jiang ,  Takuji Yamaguchi ,  Kazuhiro Tanaka ,  Takeshi Wakamatsu ,  Hiroaki Nishimura

IPC分类号： A61K31/435 ,  A61K31/439 ,  A61K31/44 ,  A61K31/4427 ,  A61K31/443 ,  A61K31/444 ,  A61K31/4748 ,  A61K36/18 ,  A61P21/00 ,  A61P25/28 ,  C07D221/22 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D221/06

CPC分类号： C07D401/06 ,  C07D221/22 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12

摘要： The present invention relates to novel huperzine A derivatives of formula (II), wherein Y is ##STR1## or R" and Y together form .dbd.CH; R is (C.sub.1 -C.sub.5) alkyl, ##STR2## wherein n is 0 or 1, X is H, (C.sub.1 -C.sub.5) alkyl; (C.sub.1 -C.sub.5) alkyloxy; nitro, halogen, carboxy, alkyloxycarbonyl, hydroxymethyl, hydroxy, amino substituted by bis-(C.sub.1 -C.sub.5) alkyl; --(CH.sub.2).sub.m COOZ, wherein m=0-5, Z is H or (C.sub.1 -C.sub.5) alkyl; --CH.dbd.CH--G, wherein G is phenyl, furanyl, carboxy, alkyloxycarbonyl; and dihydro- or tetrahydro-pyridyl substituted by (C.sub.1 -C.sub.5) alkyl at the nitrogen atom; R' is H, (C.sub.1 -C.sub.5) alkyl, pyridoyl, benzoyl substituted by (C.sub.1 -C.sub.5) alkyloxy; R" is H or (C.sub.1 -C.sub.5) alkyl; processes for their use as acetylcholinesterase inhibitor. ##STR3##

摘要翻译： PCT No.PCT / CN95 / 00100 Sec。 371日期：1997年6月27日 102（e）日期1997年6月27日PCT提交1995年12月26日PCT公布。 公开号WO96 / 20176 日期：1996年7月4日本发明涉及式（Ⅱ）的新型石杉碱甲衍生物，其中Y为或R“和Y一起形成= CH; R为（C 1 -C 5）烷基，其中n为0或1，X为H，（C 1 -C 5）烷基; （C1-C5）烷氧基; 硝基，卤素，羧基，烷氧基羰基，羟甲基，羟基，被双 - （C 1 -C 5）烷基取代的氨基; - （CH 2）m COOZ，其中m = 0-5，Z是H或（C 1 -C 5）烷基; -CH = CH-G，其中G是苯基，呋喃基，羧基，烷氧基羰基; 在氮原子被（C 1 -C 5）烷基取代的二氢或四氢吡啶基; R'是H，（C1-C5）烷基，吡啶基，（C1-C5）烷氧基取代的苯甲酰基; R“是H或（C 1 -C 5）烷基; 它们用作乙酰胆碱酯酶抑制剂的方法。

公开(公告)号：US5826816A

公开(公告)日：1998-10-27

申请号：US735720

申请日：1996-10-23

申请人： Takuji Yamaguchi

发明人： Takuji Yamaguchi

IPC分类号： G03B17/26 ,  G03D13/00 ,  B65H19/28

CPC分类号： G03D13/003 ,  G03B17/26

摘要： A film winding apparatus for winding a film into a cartridge includes a film winding mechanism provided in an apparatus housing for turning a spool housed in the cartridge to wind the film around the spool. The film is inserted through a film inlet located on one side of the apparatus housing and fed toward the film winder. The cartridge loaded on a cartridge mount provided on another side of the apparatus housing is conveyed up to the film winding mechanism, where the cartridge is set in a film loading position. The film winding apparatus thus constructed offers easy operation without any special adjustment or treatment of the film or cartridge, yet featuring single-unit construction and portability.

摘要翻译： 一种用于将薄膜卷绕到盒中的胶片卷绕装置包括设置在装置壳体中的胶片卷绕机构，用于转动容纳在盒中的卷轴，以将卷绕在卷轴上。 将薄膜插入位于设备壳体一侧的薄膜入口并朝向薄膜卷绕机送出。 装载在设置在设备外壳另一侧的盒式安装座上的盒被传送到膜卷绕机构，其中盒被设置在胶片装载位置。 这样构造的胶片卷绕装置提供了容易的操作，而没有对胶片或胶卷进行任何特别的调节或处理，但是具有单一的结构和便携性。

公开(公告)号：US5765067A

公开(公告)日：1998-06-09

申请号：US731980

申请日：1996-10-23

申请人： Takuji Yamaguchi

发明人： Takuji Yamaguchi

IPC分类号： G03B1/00 ,  G03D13/00 ,  G03F1/00 ,  G03F3/08 ,  G03F7/00 ,  H04N1/52 ,  G03B1/18

CPC分类号： G03B1/00 ,  G03D13/003

摘要： A film rewinder for rewinding film from a film cartridge to an intermediate cartridge. Its driving unit for rotating the film cartridge spool is also used to drive a tool for separating the film trailing end from the film cartridge spool. The film cartridge has a tool guide, so that the entire device is sufficiently compact. The film rewinder has a film cartridge receptacle and a winding unit for winding the film fed from the film cartridge into the intermediate cartridge. A film guide is provided between the receptacle and the winding unit. The spools of the two cartridges are driven by separate motors independently of each other. The tool is an arcuate member adapted to be pivoted in a circular path by the motor for the film cartridge. In order to minimize the length of the film guide and thus to minimize the size of the entire film rewinder, the film guide is provided with a release guide.

摘要翻译： 一种用于将胶片从胶片暗盒重新卷绕到中间暗盒的胶片复卷机。 其用于旋转胶片暗盒卷轴的驱动单元也用于驱动用于将胶片尾端与暗盒卷轴分离的工具。 胶片暗盒具有工具引导件，使得整个装置足够紧凑。 胶片复卷机具有胶卷盒接收器和用于将从暗盒馈送的胶片卷绕到中间暗盒中的卷绕单元。 在插座和卷绕单元之间提供胶片引导件。 两个墨盒的线轴彼此独立地由独立的马达驱动。 该工具是弧形构件，其适于通过用于暗盒的电动机以圆形路径枢转。 为了使薄膜引导件的长度最小化并且因此使整个复卷机的尺寸最小化，薄膜导向器设置有释放引导件。

公开(公告)号：US5725170A

公开(公告)日：1998-03-10

申请号：US655826

申请日：1996-05-31

申请人： Takuji Yamaguchi

发明人： Takuji Yamaguchi

IPC分类号： G03C3/00 ,  G03B17/30 ,  G03D13/00 ,  G03B17/26

CPC分类号： G03B17/30

摘要： A film cartridge permits efficient resetting of a film stored in a film container. A cover is mounted on a cartridge body so as to be movable between an open position and a closed position. In the closed position, a film storage space is defined by the cover and the cartridge body. A film inlet/outlet slit communicates with the outside of the film storage space. A mounted in the film storage space are a spool and a guide plate for guiding a film inserted into the film storage space onto the outer periphery of the spool. The guide plate is pivotally supported. A roller is rotatably mounted on the end of the guide plate opposite the outer periphery of the spool. The guide plate is biased by a spring so that the roller is pressed against the spool. A film inserted through the film inlet/outlet into the film storage space is guided into between the spool and the roller by the guide plate. The spool is rotated in this state to wind the film around the spool.

摘要翻译： 胶片暗盒允许有效地重置存储在胶片容器中的胶片。 盖子安装在盒体上，以便能够在打开位置和关闭位置之间移动。 在关闭位置，由盖和盒体限定胶片存放空间。 薄膜入口/出口狭缝与薄膜存储空间的外部连通。 安装在胶片储存空间中的A是一个卷轴和一个引导板，用于将插入到胶片储存空间中的胶片引导到卷轴的外周。 引导板枢转地支撑。 辊子可旋转地安装在引导板的与卷轴的外周边相对的端部上。 引导板被弹簧偏压，使得辊被压靠在卷轴上。 通过薄膜入口/出口插入薄膜存储空间中的薄膜通过导板被引导到卷轴和滚筒之间。 阀芯在此状态下旋转以将胶片缠绕在卷轴上。

公开(公告)号：US5675023A

公开(公告)日：1997-10-07

申请号：US469682

申请日：1995-06-06

申请人： Yasushi Igarashi ,  Takuji Yamaguchi ,  Yoshimitsu Ogawa ,  Mika Tomita ,  Hiroko Hayashi ,  Toshitsugu Sato ,  Kunio Hosaka

发明人： Yasushi Igarashi ,  Takuji Yamaguchi ,  Yoshimitsu Ogawa ,  Mika Tomita ,  Hiroko Hayashi ,  Toshitsugu Sato ,  Kunio Hosaka

IPC分类号： C07D311/54 ,  C07D405/12 ,  C07D417/12 ,  C07D405/02 ,  C07D407/12

CPC分类号： C07D405/12 ,  C07D311/54 ,  C07D417/12

摘要： The present invention relates to a chromone derivative and an aldose reductase inhibitor comprising said compound as efective component, which is represented by the following formula: ##STR1## wherein R.sub.1 and R.sub.2 each represent a lower alkyl group, etc., R.sub.3 represents an oxygen atom, a sulfur atom, etc., R.sub.7 represents a phenyl group substituted or not substituted, etc., and R represents a hydrogen atom or a lower alkoxy group. The present compounds exhibit superior inhititory action on aldose reductase and are useful for the treatment of various complications of diseases in diabetes, such as cataract, retinopathy, keratopathy, nephropathy, and neuropathy.

摘要翻译： 本发明涉及色酮衍生物和醛糖还原酶抑制剂，其包含作为有效成分的所述化合物，其由下式表示：其中R 1和R 2各自表示低级烷基等，R 3表示氧原子 ，硫原子等，R7表示取代或未取代的苯基等，R表示氢原子或低级烷氧基。 本发明化合物对醛糖还原酶表现出优异的抑制作用，可用于治疗糖尿病诸如白内障，视网膜病变，角膜病，肾病和神经病变的各种并发症。

公开(公告)号：US4978758A

公开(公告)日：1990-12-18

申请号：US355624

申请日：1989-05-23

申请人： Masayasu Kurono ,  Yasuaki Kondo ,  Takuji Yamaguchi ,  Kenji Miura ,  Toshinao Usui ,  Naofumi Terada ,  Kyoichi Asano ,  Kuniharu Mizuno ,  Akira Matsubara ,  Noriaki Kato ,  Kiichi Sawai ,  Ryoichi Unno ,  Hiroshi Ozawa ,  Masato Fukushima

发明人： Masayasu Kurono ,  Yasuaki Kondo ,  Takuji Yamaguchi ,  Kenji Miura ,  Toshinao Usui ,  Naofumi Terada ,  Kyoichi Asano ,  Kuniharu Mizuno ,  Akira Matsubara ,  Noriaki Kato ,  Kiichi Sawai ,  Ryoichi Unno ,  Hiroshi Ozawa ,  Masato Fukushima

IPC分类号： C07D311/24 ,  C07D491/10 ,  C07D491/107 ,  C07D495/10

CPC分类号： C07D491/10 ,  C07D311/24 ,  C07D495/10

摘要： Hydantoin derivatives and salts thereof, intermediates therefor, process for the preparation thereof, and medicines containing the derivative, wherein said derivatives have the formula ##STR1## wherein one of V and W is hydrogen and the other is a halogenomethyl group, 1H-tetrazol-5-yl radical, --COOR group,in which R is hydrogen atom, an alkyl group, --(CH.sub.2 CH.sub.2 O)nCH.sub.3 group (n is an integer of 1 to 113) or substituted phenyl, ##STR2## group, in which R.sub.1 and R.sub.2 are same or different independently, each is hydrogen atom, an alkyl group, substituted phenyl or --(CH.sub.2 CH.sub.2 O)nCH.sub.3 group (n has the meaning as referred to) or R.sub.1 may form a heterocyclic ring together with R.sub.2 and nitrogen or oxygen atom, --CH.sub.2 OR.sub.3 group or ##STR3## group, in which R.sub.3 and R.sub.4 are same or different independently and each is hydrogen atom or an alkyl group,X is oxygen or sulfur atom, and Y and Z are same or different independently and each is hydrogen atom, a halogen atom, alkyl group, alkoxy group, alkylmercapto group, nitro radical or --NHR.sub.5 group, in which R.sub.5 is hydrogen atom or an acyl group.The derivatives and salts thereof are useful for the treatment of complications of diabetes.

公开(公告)号：US5909853A

公开(公告)日：1999-06-08

申请号：US806708

申请日：1997-02-27

申请人： Takuji Yamaguchi ,  Masasuke Funase

发明人： Takuji Yamaguchi ,  Masasuke Funase

IPC分类号： G03D15/00 ,  B65H19/12 ,  G03D13/00 ,  G03B23/02

CPC分类号： G03D13/003

摘要： A film-rewinding apparatus to rewind a film from a cartridge into a container which can accommodate the film therein by inserting the film from an opening of the container. The apparatus comprises: a cartridge-supporting portion which supports the cartridge; a shielding door driving mechanism for opening and closing the shielding door; a spool-driving mechanism for feeding the film out by driving the spool; a container-supporting portion for supporting the container; and a film-dismounting mechanism for dismounting the film from the spool. The film-rewinding apparatus can easily perform rewinding only by operating a handle or a lever, or by switching operation, after the cartridge and the intermediate magazine are set and the cover is locked.

摘要翻译： 一种胶片重绕装置，用于将胶片从胶卷盒中倒带到容器中，该容器可以通过从容器的开口插入胶片来容纳胶片。 该装置包括：支撑盒的盒支撑部; 用于打开和关闭屏蔽门的屏蔽门驱动机构; 卷轴驱动机构，用于通过驱动卷轴来输送胶卷; 用于支撑容器的容器支撑部分; 以及用于从卷轴拆卸胶片的胶片拆卸机构。 复卷装置可以通过操作手柄或杠杆或通过切换操作容易地进行倒带，在盒和中间盒被设置并且盖被锁定之后。

公开(公告)号：US5908131A

公开(公告)日：1999-06-01

申请号：US740001

申请日：1996-10-23

申请人： Takuji Yamaguchi

发明人： Takuji Yamaguchi

IPC分类号： G03C3/00 ,  G03D3/00 ,  G03D13/00 ,  G03D17/00 ,  B65D45/16

CPC分类号： G03D13/005 ,  Y10T292/702

摘要： A locking device for use in a processing device for processing photosensitive material such as photographic film has a light-shield cover that can be unlocked without moving a knob plate. The knob plate has an engaging member for locking the light-shield cover. An unlocking mechanism is provided to unlock the light-shield cover without moving the knob plate. The unlocking mechanism has a pushing head, and an unlocking lever having a tip engageable with the engaging member and adapted to be pushed by the pushing head. By moving the unlocking lever with the pushing head until its tip disengages from the engaging member, the engaging member can pass through a cutout, so that the light-shield cover can be unlocked and opened.

摘要翻译： 用于处理感光材料如感光胶片的处理装置中的锁定装置具有可以在不移动旋钮板的情况下解锁的遮光罩。 手柄板具有用于锁定遮光罩的接合构件。 提供解锁机构来解锁遮光罩而不移动钮板。 解锁机构具有推动头和解锁杆，其具有可与接合构件接合并适于被推动头推动的尖端。 通过用推动头移动解锁杆直到其顶端脱离接合构件，接合构件可以穿过切口，使得遮光罩可以被解锁和打开。